Bioprocess and Biosystems Engineering provides an international peer-reviewed forum to facilitate the discussion between engineering and biological science to find efficient solutions in the development and improvement of bioprocesses. The aim of the journal is to focus more attention on the multidisciplinary approaches for integrative bioprocess design. Of special interest are the rational manipulation of biosystems through metabolic engineering techniques to provide new biocatalysts as well as the model based design of bioprocesses (up-stream processing, bioreactor operation and downstream processing) that will lead to new and sustainable production processes.Contributions are targeted at new approaches for rational and evolutive design of cellular systems by taking into account the environment and constraints of technical production processes, integration of recombinant technology and process design, as well as new hybrid intersections such as bioinformatics and process systems engineering. Manuscripts concerning the design, simulation, experimental validation, control, and economic as well as ecological evaluation of novel processes using biosystems or parts thereof (e.g., enzymes, microorganisms, mammalian cells, plant cells, or tissue), their related products, or technical devices are also encouraged.The Editors will consider papers for publication based on novelty, their impact on biotechnological production and their contribution to the advancement of bioprocess and biosystems engineering science. Submission of papers dealing with routine aspects of bioprocess engineering (e.g., routine application of established methodologies, and description of established equipment) are discouraged.
生物过程和生物系统工程提供了一个国际性的同行评审论坛，以促进工程和生物科学之间的讨论，找到有效的解决方案，在开发和改进生物过程。该杂志的目的是集中更多的注意力在综合生物过程设计的多学科方法。特别感兴趣的是通过代谢工程技术合理操纵生物系统，以提供新的生物催化剂，以及基于模型的生物过程设计（上游处理，生物反应器操作和下游加工），这将导致新的和可持续的生产工艺。通过考虑蜂窝系统的环境和限制，致力于蜂窝系统的合理和进化设计的新方法。技术生产过程、重组技术和过程设计的整合，以及新的混合交叉点，如生物信息学和过程系统工程。关于使用生物系统或其部分的新工艺的设计、模拟、实验验证、控制、经济学和生态学评估的手稿（例如：酶、微生物、哺乳动物细胞、植物细胞或组织）、其相关产品或技术装置。编辑将根据新奇、对生物技术生产的影响以及对生物过程和生物系统工程科学进步的贡献来考虑发表论文。提交有关生物工艺工程常规方面的论文（例如：常规应用已建立的方法和描述已建立的设备）。
Model-assisted Design of Experiments as a concept for knowledge-based bioprocess development
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02089-7
Polyhydroxybutyrate production in halophilic marine bacteria Vibrio proteolyticus isolated from the Korean peninsula
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-018-02066-6
Enhanced ethanol production from industrial lignocellulose hydrolysates by a hydrolysate-cofermenting Saccharomyces cerevisiae strain
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02090-0
Respirometry as a tool to quantify kinetic parameters of microalgal mixotrophic growth
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02087-9
Synthesis, characterization and pharmacological potential of green synthesized copper nanoparticles
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02173-y
Comparison of bacterial community structure and function under different petroleum hydrocarbon degradation conditions
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02227-1
Fermentation optimization and kinetic model for high cell density culture of a probiotic microorganism: Lactobacillus rhamnosus LS-8
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02246-y
Selenium reduction by a defined co-culture of Shigella fergusonii strain TB42616 and Pantoea vagans strain EWB32213-2
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02134-5
Organic acids as antimicrobial food agents: applications and microbial productions
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02256-w
Microbiota adaptation after an alkaline pH perturbation in a full-scale UASB anaerobic reactor treating dairy wastewater
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02198-3
Sequencing, cloning, and heterologous expression of cyclomaltodextrin glucanotransferase of Bacillus firmus strain 37 in Bacillus subtilis WB800
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-018-02068-4
A high-throughput screening method for improved R-2-(4-hydroxyphenoxy)propionic acid biosynthesis
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02154-1
Enzymatic synthesis of structured lipids enriched with conjugated linoleic acid and butyric acid: strategy consideration and parameter optimization
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02223-5
Regulation of different electron acceptors on petroleum hydrocarbon biotransformation to final products in activated sludge biosystems
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02070-4
Kinetic identification of phenolic compounds and potential production of caffeic acid by Ganoderma lipsiense in solid-state fermentation
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02131-8
Integrated thermophilic enzyme-immobilized reactor and high-rate biological reactors for treatment of palm oil-containing wastewater without sludge production
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02104-x
A phase diagram-based toolbox to assess the impact of freeze/thaw ramps on the phase behavior of proteins
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02215-5
Controlling methane and hydrogen production from cheese whey in an EGSB reactor by changing the HRT
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02265-9
Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch processes in single-use bioreactors
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02216-4
Highly efficient synthesis of boldenone from androst-4-ene-3,17-dione by Arthrobacter simplex and Pichia pastoris ordered biotransformation
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02092-y
Bioprocess development of a stable FUT8−/−-CHO cell line to produce defucosylated anti-HER2 antibody
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02124-7
High-level expression of Bacillus amyloliquefaciens laccase and construction of its chimeric variant with improved stability by domain substitution
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02236-0
Efficient production of polysaccharide by Chaetomium globosum CGMCC 6882 through co-culture with host plant Gynostemma pentaphyllum
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02169-8
Production of conidia of the entomopathogenic fungus Metarhizium anisopliae ICB 425 in a tray bioreactor
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02172-z
Advanced nitrogen removal without addition of external carbon source in an anaerobic/aerobic/anoxic sequencing batch reactor
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02148-z
Evaluation of anammox pathway recovery after high COD loading using water quality, molecular biology and isotope labelling analysis
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02260-0
Lipid extraction from Nannochloropsis oceanica biomass after extrusion pretreatment with twin-screw extruder: optimization of processing parameters and comparison of lipid quality
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02263-x
Metaheuristic approaches in biopharmaceutical process development data analysis
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02147-0
Modification of carbon felt anode with graphene/Fe2O3 composite for enhancing the performance of microbial fuel cell
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02233-3
Pretreatment of corn cob in [EMIM][OAc] and [EMIM][OAc]/ethanol (water)
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02126-5
The mixed culture of microalgae Chlorella pyrenoidosa and yeast Yarrowia lipolytica for microbial biomass production
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02138-1
Biogas production: evaluation of the influence of K2FeO4 pretreatment of maple leaves (Acer platanoides) on microbial consortia composition
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02112-x
Performance of an air-cathode microbial fuel cell under varied relative humidity conditions in the cathode chamber
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02122-9
FeedER: a feedback-regulated enzyme-based slow-release system for fed-batch cultivation in microtiter plates
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02180-z
Applications of off-gas mass spectrometry in fed-batch mammalian cell culture
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02242-2
On-line glucose monitoring by near infrared spectroscopy during the scale up steps of mammalian cell cultivation process development
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02091-z
Evaluation of predominant factor for shortcut biological nitrogen removal in sequencing batch reactor at ambient temperature
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02117-6
Influence of linear alkylbenzene sulfonate and ethanol on the degradation kinetics of domestic sewage in co-digestion with commercial laundry wastewater
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02152-3
Design of a synthetic miniR1 plasmid and its production by engineered Escherichia coli
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02129-2
The potential of a natural biopolymeric flocculant, ε-poly-l-lysine, for harvesting Chlorella ellipsoidea and its sustainability perspectives for cost and toxicity
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02098-6
Optimized design of a novel filter brick in denitrification deep-bed filter
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02166-x
Adaptive identification of anaerobic digestion process for biogas production management systems
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02203-9
High-flux simultaneous screening of common foodborne pathogens and their virulent factors\n
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02267-7
Optimization of fermentation conditions for carotenoid production in the radiation-resistant strain Deinococcus xibeiensis R13
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-018-02069-3
Rational enhancement of enzyme-catalyzed enantioselective reaction by construction of recombinant enzymes based on additive strategy
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02170-1
Effect of design dark fraction on the loss of biomass productivities in photobioreactors
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02217-3
Promoted performance of microbial fuel cells using Escherichia coli cells with multiple-knockout of central metabolism genes
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02229-z
N2O production from hydroxylamine oxidation and corresponding hydroxylamine oxidoreductase involved in a heterotrophic nitrifier A. faecalis strain NR
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02191-w
Structural effect of amine N-oxides on the facilitation of α-glucosidase-catalyzed hydrolysis reactions
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02248-w
Embedding live bacteria in porous hydrogel/ceramic nanocomposites for bioprocessing applications
来源期刊：Bioprocess and Biosystems EngineeringDOI：10.1007/s00449-019-02119-4
