Biomolecules & Therapeutics (Biomolecules & Therapeutics) (Print ISSN 1976-9148, Online ISSN 2005-4483) is an international, peer-reviewed, open access journal that covers pharmacological and toxicological fields related to bioactive molecules and therapeutics. It was launched in 1993 as "The Journal of Applied Pharmacology (ISSN 1225-6110)", and renamed "Biomolecules & Therapeutics" (Biomol Ther: abbreviated form) in 2008 (Volume 16, No. 1). It is published bimonthly in January, March, May, July, September and November. All manuscripts should be creative, informative, and contribute to the development of new drugs. Articles in the following categories are published: review articles and research articles.
Biomolecules & Therapeutics (Biomolecules & Therapeutics)（印刷版ISSN 1976-9148，在线版ISSN 2005-4483）是一本国际性、同行评审的开放获取期刊，涵盖与生物活性分子和治疗相关的药理学和毒理学领域。 1993年创刊为《The Journal of Applied Pharmacology》（ISSN 1225-6110），2008年更名为《Biomolecules & Therapeutics》（Biomol Ther：缩写形式）（第16卷第1期）。它在1月、3月、5月、7月、9月和11月出版双月刊。所有稿件都应具有创造性、信息量大，并有助于新药的开发。发表以下类别的文章：评论文章和研究文章。
Resveratrol: Twenty Years of Growth, Development and Controversy
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.176
Possible Effects of Radiofrequency Electromagnetic Field Exposure on Central Nerve System
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.152
Roles of Mesenchymal Stem Cells in Tissue Regeneration and Immunomodulation
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2017.260
Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.047
Flavonoids: Broad Spectrum Agents on Chronic Inflammation
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.034
Neuroprotective Effect of β-Lapachone in MPTP-Induced Parkinson’s Disease Mouse Model: Involvement of Astroglial p-AMPK/Nrf2/HO-1 Signaling Pathways
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.234
Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.133
Analysis of the Expression and Regulation of PD-1 Protein on the Surface of Myeloid-Derived Suppressor Cells (MDSCs)
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.201
Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.107
Differentiation of Human Mesenchymal Stem Cells towards Neuronal Lineage: Clinical Trials in Nervous System Disorders
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.065
Epicatechin Prevents Methamphetamine-Induced Neuronal Cell Death via Inhibition of ER Stress
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.092
A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.074
Niacinamide Protects Skin Cells from Oxidative Stress Induced by Particulate Matter
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.061
Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.041
Autophagy Is a Potential Target for Enhancing the Anti-Angiogenic Effect of Mebendazole in Endothelial Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.222
Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.183
Neuroprotective Effects of 6-Shogaol and Its Metabolite, 6-Paradol, in a Mouse Model of Multiple Sclerosis
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.089
Particulate Matter-Induced Aryl Hydrocarbon Receptor Regulates Autophagy in Keratinocytes
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.025
Novel Isoquinolinamine and Isoindoloquinazolinone Compounds Exhibit Antiproliferative Activity in Acute Lymphoblastic Leukemia Cells.
来源期刊：Biomolecules & therapeuticsDOI：10.4062/biomolther.2019.007
Recent Trends in Cyclic Peptides as Therapeutic Agents and Biochemical Tools
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.082
Udenafil Induces the Hair Growth Effect of Adipose-Derived Stem Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.195
PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.147
Tumour Regression via Integrative Regulation of Neurological, Inflammatory, and Hypoxic Tumour Microenvironment
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.135
Etoposide Induces Mitochondrial Dysfunction and Cellular Senescence in Primary Cultured Rat Astrocytes
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.151
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.071
Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.175
Natural Products as Sources of Novel Drug Candidates for the Pharmacological Management of Osteoarthritis: A Narrative Review
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.139
β-Amyrin Ameliorates Alzheimer’s Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.024
Spinosin Attenuates Alzheimer’s Disease-Associated Synaptic Dysfunction via Regulation of Plasmin Activity
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.076
Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.123
Novel Isoquinolinamine and Isoindoloquinazolinone Compounds Exhibit Antiproliferative Activity in Acute Lymphoblastic Leukemia Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/BIOMOLTHER.2018.199
Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.090
Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.056
The Role of a Neurovascular Signaling Pathway Involving Hypoxia-Inducible Factor and Notch in the Function of the Central Nervous System
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.119
Anxiolytic Action of Taurine via Intranasal Administration in Mice
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.218
Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.149
Justicidin A Reduces β-Amyloid via Inhibiting Endocytosis of β-Amyloid Precursor Protein
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.112
Modulation of Immunosuppression by Oligonucleotide-Based Molecules and Small Molecules Targeting Myeloid-Derived Suppressor Cells
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.069
Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.216
Catalpol and Mannitol, Two Components of Rehmannia glutinosa, Exhibit Anticonvulsant Effects Probably via GABAA Receptor Regulation
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.130
Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.113
Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.107
Melatonin-Induced PGC-1α Improves Angiogenic Potential of Mesenchymal Stem Cells in Hindlimb Ischemia
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.131
Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.213
Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.203
Inhibitory Effect of Probenecid on Osteoclast Formation via JNK, ROS and COX-2
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.047
Suppressor of Variegation 3–9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.021
Lodoxamide Attenuates Hepatic Fibrosis in Mice: Involvement of GPR35
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2018.227
Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level
来源期刊：Biomolecules & TherapeuticsDOI：10.4062/biomolther.2019.013
