Clinical Epigenetics, the official journal of the Clinical Epigenetics Society, is an open access, peer-reviewed journal that encompasses all aspects of epigenetic principles and mechanisms in relation to human disease, diagnosis and therapy. Clinical trials and research in disease model organisms are particularly welcome.
《临床表观遗传学》是临床表观遗传学学会的官方期刊,是一本开放获取、同行评审的期刊,涵盖了与人类疾病、诊断和治疗相关的表观遗传学原理和机制的所有方面。特别欢迎对疾病模型生物体进行临床试验和研究。
The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0656-7
The emerging role of epigenetics in human autoimmune disorders
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0632-2
Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0635-z
Hsa_circRNA_0054633 is highly expressed in gestational diabetes mellitus and closely related to glycosylation index
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0610-8
Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0658-5
Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0688-z
Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0778-y
DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0622-4
A genome-wide DNA methylation signature for SETD1B-related syndrome
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0749-3
The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0766-2
Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0758-2
Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC)
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0715-0
Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenome
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0702-5
Methylation at cg05575921 of a smoking-related gene (AHRR) in non-smoking Taiwanese adults residing in areas with different PM2.5 concentrations
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0662-9
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0739-5
Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0628-y
The E3 ubiquitin ligase RNF40 suppresses apoptosis in colorectal cancer cells
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0698-x
Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0643-z
Prognostic implications and interaction of L1 methylation and p53 expression statuses in advanced gastric cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0661-x
Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0764-4
Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0701-6
Urinary DNA methylation biomarkers for prediction of prostate cancer upgrading and upstaging
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0716-z
Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0731-0
Epigenetic silencing of MEIS2 in prostate cancer recurrence
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0742-x
DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0666-5
The phenotypic variations of multi-locus imprinting disturbances associated with maternal-effect variants of NLRP5 range from overt imprinting disorder to apparently healthy phenotype
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0760-8
Smoking-associated AHRR demethylation in cord blood DNA: impact of CD235a+ nucleated red blood cells
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0686-1
DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0733-y
Clustered protocadherins methylation alterations in cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0695-0
Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0678-1
DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0679-0
Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0752-8
Replicated methylation changes associated with eczema herpeticum and allergic response
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0714-1
RFX1 downregulation contributes to TLR4 overexpression in CD14+ monocytes via epigenetic mechanisms in coronary artery disease
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0646-9
Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0660-y
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0639-8
Machine-learned analysis of global and glial/opioid intersection–related DNA methylation in patients with persistent pain after breast cancer surgery
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0772-4
Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0710-5
SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0693-2
Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0740-z
ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0665-6
Ovarian cancer detection by DNA methylation in cervical scrapings
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0773-3
Smoking index, lifestyle factors, and genomic instability assessed by single-cell gel electrophoresis: a cross-sectional study in subjects from Yucatan, Mexico
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0745-7
Random forest-based modelling to detect biomarkers for prostate cancer progression
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0736-8
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0729-7
Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0781-3
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0775-1
Epigenetic age acceleration and metabolic syndrome in the coronary artery risk development in young adults study
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0767-1
Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0699-9
Correction to: DNA methylation signature is prognostic of choroid plexus tumor aggressiveness
来源期刊:Clinical EpigeneticsDOI:10.1186/s13148-019-0737-7