Science Immunology will publish original, peer-reviewed, science-based research articles that report critical advances in all areas of immunological research, including important new tools and techniques. The editors encourage submission of original research findings from all areas within the broad field of immunology from all model organisms, including humans. Areas covered range from basic studies into the biology of innate and adaptive immunity (immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology) to immune contributions to health and disease (host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency). The editors and an international advisory group of scientists will hold Science Immunology articles to the same high-quality standard that is the hallmark of the Science family of journals.
《科学免疫学》将发表原创的、同行评议的、以科学为基础的研究文章，报告免疫学研究所有领域的关键进展，包括重要的新工具和技术。编辑们鼓励提交来自包括人类在内的所有模式生物的广泛免疫学领域内所有领域的原始研究结果。涵盖的领域从先天性和适应性免疫的生物学基础研究（免疫细胞发育和分化、免疫基因组学、系统免疫学、结构免疫学、抗原呈递、免疫代谢和粘膜免疫学）到免疫对健康和疾病的贡献（宿主防御、炎症、癌症免疫学、自身免疫、过敏、移植和免疫缺陷）。编辑和一个国际科学家顾问小组将保持科学免疫学文章的高质量标准，这是科学家族期刊的标志。
Location, location, location: Tissue resident memory T cells in mice and humans
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aas9673
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy individuals
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav8995
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw2004
Human natural killer cells mediate adaptive immunity to viral antigens
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aat8116
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw6647
Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau9657
Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aay5199
T cell receptor–triggered nuclear actin network formation drives CD4+ T cell effector functions
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav1987
B cells engineered to express pathogen-specific antibodies protect against infection
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax0644
VEGF-A drives TOX-dependent T cell exhaustion in anti–PD-1–resistant microsatellite stable colorectal cancers
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aay0555
GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax8189
Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav7638
Interleukin-36γ–producing macrophages drive IL-17–mediated fibrosis
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax4783
Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau6905
Human “TH9” cells are a subpopulation of PPAR-γ+ TH2 cells
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aat5943
Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau2710
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aar3054
Transplanting organs from pigs to humans
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau6298
Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau9079
Conversion of antigen-specific effector/memory T cells into Foxp3-expressing Treg cells by inhibition of CDK8/19
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw2707
Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau9039
RELMα-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aau3814
Neutrophils restrain allergic airway inflammation by limiting ILC2 function and monocyte–dendritic cell antigen presentation
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax7006
Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw6693
High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav0860
Modulation of asymmetric cell division as a mechanism to boost CD8+ T cell memory
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav1730
Should I stay or should I go—Reconciling clashing perspectives on CD4+ tissue-resident memory T cells
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax5595
CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav1263
Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav6473
Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav7501
Gab3 is required for IL-2– and IL-15–induced NK cell expansion and limits trophoblast invasion during pregnancy
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aav3866
Lifting the veil on macrophage diversity in tissue regeneration and fibrosis
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaz0749
Antibiotics bug the immune response
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaz6074
Clec10a regulates mite-induced dermatitis
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax6908
Game of clones: How measles remodels the B cell landscape
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaz4195
Myeloid cells in the central nervous system: So similar, yet so different
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw2841
Slamming the brakes on lupus with CAR T cells
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax3916
A perfect storm: Genetics and anticommensal antibodies shore up type 1 diabetes
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw3345
Belly-born B cells bathe the brain
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw7721
Binding is not enough; autoantibodies do more to garner complements
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax9510
Adding intestinal insult to skin injury
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aat0809
A ten-acious cytokine for a tenacious infection
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaw7720
It takes 2 TOXes to Tfh Tango
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aba3067
Interleukin-17 receptor D: An orphan receptor finds a home in the skin
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax0687
To debug or not to debug, a question worth asking
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aaz9474
TB or not TB: Type 3 ILCs may decide
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aay7254
Leukemic stem cells hiding in plain sight
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aay7253
Placentation and antitumor immunity regulated by a scaffolding protein in NK cells
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax9589
Luring T cells into a gray area
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax3917
T cells have seen it all before
来源期刊：Science ImmunologyDOI：10.1126/sciimmunol.aax1019
