Cell Discovery, published by Springer Nature in partnership with the Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS), aims to provide an open access platform for scientists to publish their high quality works. Cell Discovery publishes results of high significance and broad interest in all areas of molecular and cell biology, including (but not limited to) the following topics:cell growth and differentiation,signal transduction,apoptosis,stem cells,development,immunology,neurosciences,plant cell biology,chromatin modulation,epigenetics and transcription.
《细胞发现》由Springer Nature与中国科学院上海生命科学研究院（SIBS）合作出版，旨在为科学家提供一个开放的平台，发表他们的高质量作品。《细胞发现》发表了在分子和细胞生物学所有领域具有高度重要性和广泛意义的结果，包括（但不限于）以下主题：细胞生长和分化、信号转导、凋亡、干细胞、发育、免疫学、神经科学、植物细胞生物学、染色质调节、表观遗传学和转录。
A chemical approach for global protein knockdown from mice to non-human primates
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0079-1
Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0075-5
Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0089-7
A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0076-4
Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0087-9
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0084-z
Defining an evolutionarily conserved role of GW182 in circular RNA degradation
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0113-y
SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0068-4
Molecular basis for hierarchical histone de-β-hydroxybutyrylation by SIRT3
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0103-0
Regrowth-delay body as a bacterial subcellular structure marking multidrug-tolerant persisters
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0080-3
Mixed-lineage leukemia protein 2 suppresses ciliary assembly by the modulation of actin dynamics and vesicle transport
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0100-3
Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0077-3
Single-cell imaging and transcriptomic analyses of endogenous cardiomyocyte dedifferentiation and cycling
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0095-9
Efficient and precise base editing in rabbits using human APOBEC3A-nCas9 fusions
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0099-5
Optimizing genome editing strategy by primer-extension-mediated sequencing
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0088-8
Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0090-1
Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0119-5
Artificial sgRNAs engineered for genome editing with new Cas12b orthologs
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0091-0
Identification of markers for migrasome detection
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0093-y
Architecture of Saccharomyces cerevisiae SAGA complex
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0094-x
Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0136-4
Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling
来源期刊：Cell discoveryDOI：10.2210/PDB6AKK/PDB
A novel approach to remove the batch effect of single-cell data
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0114-x
Targeting JNK pathway promotes human hematopoietic stem cell expansion
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0072-8
Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0074-6
Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0073-7
Structural insight into human N6amt1–Trm112 complex functioning as a protein methyltransferase
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0121-y
ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0110-1
More than one antibody of individual B cells revealed by single-cell immune profiling.
来源期刊：Cell discoveryDOI：10.1038/s41421-019-0137-3
Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0086-x
Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0126-6
MLL is required for miRNA-mediated translational repression
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0111-0
CRISPR/ddCas12a-based programmable and accurate gene regulation
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0085-y
Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0130-x
Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0106-x
Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0120-z
Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0131-9
The metacaspase Yca1 maintains proteostasis through multiple interactions with the ubiquitin system
来源期刊：Cell DiscoveryDOI：10.1038/s41421-018-0071-9
Structural insights into tubulin detyrosination by vasohibins-SVBP complex
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0133-7
Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage
来源期刊：Cell discoveryDOI：10.2210/PDB6JG9/PDB
Twin-peak temporal regulation during human neocortical development.
来源期刊：Cell discoveryDOI：10.1038/s41421-019-0129-3
Pwp1 regulates telomere length by stabilizing shelterin complex and maintaining histone H4K20 trimethylation
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0116-8
Structural insights into the activation of USP46 by WDR48 and WDR20
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0102-1
MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0107-9
Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0101-2
Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0097-7
PKAc-directed interaction and phosphorylation of Ptc is required for Hh signaling inhibition in Drosophila
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0112-z
Author Correction: CRISPR-Cas12a-assisted nucleic acid detection
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0083-0
Author Correction: Targeted exon skipping with AAV-mediated split adenine base editors
来源期刊：Cell DiscoveryDOI：10.1038/s41421-019-0125-7
