Molecular Metabolism is committed to serving as a platform reporting breakthrough discoveries in energy homeostasis and in the etiology, development, treatment and associated health consequences of metabolic disorders, such as obesity, diabetes, cardiovascular disease and cancer. The journal publishes hypothesis driven research generated with the highest standards that paves the way to a mechanistic understanding of energy homeostasis-associated behavior, physiology and dysfunction.
分子代谢致力于作为一个平台,报告能量稳态和代谢疾病(如肥胖、糖尿病、心血管疾病和癌症)的病因、发展、治疗和相关健康后果方面的突破性发现。该杂志发表的假说驱动的研究产生的最高标准,铺平了道路,以机械的理解能量稳态相关的行为,生理学和功能障碍。
Ketogenic diet in the treatment of cancer – Where do we stand?
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.026
The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.012
Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.005
Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.001
Adapt and conquer: Metabolic flexibility in cancer growth, invasion and evasion
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.021
Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: liquid or solid
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.05.010
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.004
GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.01.003
A dual Ucp1 reporter mouse model for imaging and quantitation of brown and brite fat recruitment
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.009
Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.01.001
The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.10.012
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.09.013
Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.10.005
Transcriptional and physiological roles for STAT proteins in leptin action
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.01.007
Conditional deletion of melanin-concentrating hormone receptor 1 from GABAergic neurons increases locomotor activity
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.018
Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deterioration
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.007
Comprehensive and quantitative analysis of white and brown adipose tissue by shotgun lipidomics
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.01.009
Epigenetic disturbances in obesity and diabetes: Epidemiological and functional insights
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.011
Double bond configuration of palmitoleate is critical for atheroprotection
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.004
Epigenetic regulation of diabetogenic adipose morphology
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.04.009
WWOX somatic ablation in skeletal muscles alters glucose metabolism
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.01.010
GLP-1 modulates the supramammillary nucleus-lateral hypothalamic neurocircuit to control ingestive and motivated behavior in a sex divergent manner
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.005
Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.10.007
Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.022
Identification of functional lipid metabolism biomarkers of brown adipose tissue aging
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.011
Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.006
Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.11.004
Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.009
Direct and indirect effects of liraglutide on hypothalamic POMC and NPY/AgRP neurons – Implications for energy balance and glucose control
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.07.008
Evaporative cooling provides a major metabolic energy sink
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.023
Ferritin regulates organismal energy balance and thermogenesis
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.008
HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.07.005
A role for foregut tyrosine metabolism in glucose tolerance
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.02.008
Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.003
Interaction of circulating GLP-1 and the response of the dorsolateral prefrontal cortex to food-cues predicts body weight development
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.014
Discovering metabolic disease gene interactions by correlated effects on cellular morphology
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.03.001
Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.02.005
Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.017
Analysing central metabolism in ultra-high resolution: At the crossroads of carbon and nitrogen
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.12.002
Activation of hepatic estrogen receptor-α increases energy expenditure by stimulating the production of fibroblast growth factor 21 in female mice
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.02.002
A single extra copy of Down syndrome critical region 1–4 results in impaired hepatic glucose homeostasis
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2018.12.002
miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.008
Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.12.010
Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.09.004
GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.021
α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.024
Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.08.020
The role of T cell miRNAs for regulatory T cell induction in islet autoimmunity
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.009
Informing β-cell regeneration strategies using studies of heterogeneity
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.06.004
Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation
来源期刊:Molecular MetabolismDOI:10.1016/j.molmet.2019.02.006