Inflammopharmacology is the official publication of the Gastrointestinal Section of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the Hungarian Experimental and Clinical Pharmacology Society (HECPS). Inflammopharmacology publishes papers on all aspects of inflammation and its pharmacological control emphasizing comparisons of (a) different inflammatory states, and (b) the actions, therapeutic efficacy and safety of drugs employed in the treatment of inflammatory conditions. The comparative aspects of the types of inflammatory conditions include gastrointestinal disease (e.g. ulcerative colitis, Crohn's disease), parasitic diseases, toxicological manifestations of the effects of drugs and environmental agents, arthritic conditions, and inflammatory effects of injury or aging on skeletal muscle. The journal has seven main interest areas:-Drug-Disease Interactions - Conditional Pharmacology - i.e. where the condition (disease or stress state) influences the therapeutic response and side (adverse) effects from anti-inflammatory drugs. Mechanisms of drug-disease and drug disease interactions and the role of different stress states-Rheumatology - particular emphasis on methods of measurement of clinical response effects of new agents, adverse effects from anti-rheumatic drugs-Gastroenterology - with particular emphasis on animal and human models, mechanisms of mucosal inflammation and ulceration and effects of novel and established anti-ulcer, anti-inflammatory agents, or antiparasitic agents-Neuro-Inflammation and Pain - model systems, pharmacology of new analgesic agents and mechanisms of neuro-inflammation and pain-Novel drugs, natural products and nutraceuticals - and their effects on inflammatory processes, especially where there are indications of novel modes action compared with conventional drugs e.g. NSAIDs-Muscle-immune interactions during inflammation [...]
炎症药理学是国际基础和临床药理学联合会(IUPHAR )胃肠道分会和匈牙利实验和临床药理学学会(HECPS )的官方出版物。炎症药理学发表关于炎症及其药理学控制的所有方面的论文,强调比较(a )不同的炎症状态,和(b )用于治疗炎症状况的药物的作用、治疗效果和安全性。炎性病症类型的比较方面包括胃肠道疾病(例如溃疡性结肠炎、克罗恩病) 、寄生虫病、药物和环境因素作用的毒理学表现、关节炎病症以及损伤或老化对骨骼肌的炎性影响。该杂志有七个主要兴趣领域: -药物-疾病相互作用-条件药理学-即条件(疾病或应激状态)影响抗炎药物的治疗反应和副作用。药物-疾病和药物-疾病相互作用的机制以及不同应激状态的作用-风湿病学-特别强调新药临床反应效果的测量方法,抗风湿药的副作用-胃肠病学-特别强调动物和人类模型,粘膜炎症和溃疡的机制以及新的和已确立的抗溃疡、抗炎药的作用,或抗寄生虫剂-神经炎症和疼痛-模型系统,新止痛剂的药理学和神经炎症和疼痛的机制-新药,天然产物和营养制品-及其对炎症过程的作用,特别是与常规药物相比有新的作用模式的指征时,如炎症期间NSAID -肌肉-免疫相互作用[...]
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00612-6
Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00628-y
Possible involvement of metformin in downregulation of neuroinflammation and associated behavioural changes in mice
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00638-w
International multicenter randomized, placebo-controlled phase III clinical trial of β-d-mannuronic acid in rheumatoid arthritis patients
来源期刊:InflammopharmacologyDOI:10.1007/s10787-018-00557-2
Sumatriptan protects against myocardial ischaemia–reperfusion injury by inhibition of inflammation in rat model
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00586-5
Total flavonoids from Tetrastigma hemsleyanum ameliorates inflammatory stress in concanavalin A-induced autoimmune hepatitis mice by regulating Treg/Th17 immune homeostasis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00599-0
4-Phenylbutyric acid protects against vasculitic peripheral neuropathy induced by ischaemia–reperfusion through attenuating endoplasmic reticulum stress
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00604-6
Bergapten inhibits chemically induced nociceptive behavior and inflammation in mice by decreasing the expression of spinal PARP, iNOS, COX-2 and inflammatory cytokines
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00585-6
Genipin attenuates dextran sulfate sodium-induced colitis via suppressing inflammatory and oxidative responses
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00639-9
Cilostazol add-on therapy for celecoxib synergistically inhibits proinflammatory cytokines by activating IL-10 and SOCS3 in the synovial fibroblasts of patients with rheumatoid arthritis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00605-5
Analysis of lncRNA expression profiles by sequencing reveals that lnc-AL928768.3 and lnc-AC091493.1 are novel biomarkers for disease risk and activity of rheumatoid arthritis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00666-6
Ginsenoside compound-K inhibits the activity of B cells through inducing IgD-B cell receptor endocytosis in mice with collagen-induced arthritis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00608-2
Oleic acid-containing semisolid dosage forms exhibit in vivo anti-inflammatory effect via glucocorticoid receptor in a UVB radiation-induced skin inflammation model
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00675-5
In vivo antiulcer activity, phytochemical exploration, and molecular modelling of the polyphenolic-rich fraction of Crepis sancta extract
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00637-x
Syk: a new target for attenuation of Helicobacter pylori-induced gastric mucosal inflammatory responses
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00577-6
Are peptides a solution for the treatment of hyperactivated JAK3 pathways?
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00589-2
Cysteinyl leukotriene receptor antagonism: a promising pharmacological strategy for lowering the severity of arthritis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00618-0
Anti-inflammatory role of TPCA-1 encapsulated nanosomes in porcine chondrocytes against TNF-α stimulation
来源期刊:InflammopharmacologyDOI:10.1007/s10787-018-0542-5
The granulopoietic cytokine granulocyte colony-stimulating factor (G-CSF) induces pain: analgesia by rutin
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00591-8
Effect of tranexamic acid in improving the lifespan of naturally aging mice
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00616-2
Anti-arthritic activity of ferulic acid in complete Freund’s adjuvant (CFA)-induced arthritis in rats: JAK2 inhibition
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00642-0
Evaluation of the therapeutic potential of the selective p38 MAPK inhibitor Skepinone-L and the dual p38/JNK 3 inhibitor LN 950 in experimental K/BxN serum transfer arthritis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00593-6
Therapeutic potential of quercetin on human breast cancer in different dimensions
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00660-y
Functional improvement and immune-inflammatory cytokines profile of ischaemic stroke patients after treatment with boswellic acids: a randomized, double-blind, placebo-controlled, pilot trial
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00627-z
Imatinib modulates pro-inflammatory microenvironment with angiostatic effects in experimental lung carcinogenesis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00656-8
IL-1β, IL-17A, CRP and biologics history might serve as potential markers for clinical response to etanercept in rheumatoid arthritis patients
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00624-2
Limited preventive effect of prednisone on neuropsychiatric symptoms in murine systemic lupus erythematosus
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00587-4
Thiamine, riboflavin, and nicotinamide inhibit paclitaxel-induced allodynia by reducing TNF-α and CXCL-1 in dorsal root ganglia and thalamus and activating ATP-sensitive potassium channels
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00625-1
Combinatorial therapeutic effect of resveratrol and piperine on murine model of systemic lupus erythematosus
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00662-w
Flavonoids from Rhynchosia minima root exerts anti-inflammatory activity in lipopolysaccharide-stimulated RAW 264.7 cells via MAPK/NF-κB signaling pathway
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00632-2
Urotensin-#receptor antagonist SB-706375 protected isolated rat heart from ischaemia–reperfusion injury by attenuating myocardial necrosis via RhoA/ROCK/RIP3 signalling pathway
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00598-1
Correction to: Moringa oleifera leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00636-y
The investigation of possible roles of central 5-HT7 receptors in antipyretic effect mechanism of paracetamol in LPS-induced hyperthermia model of mice
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00617-1
Role of the antioxidant properties in the gastroprotective and gastric healing activity promoted by Brazilian green propolis and the healing efficacy of Artepillin C
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00649-7
Protective effects of a polyphenol-enriched fraction of the fruit peel of Annona crassiflora Mart. on acute and persistent inflammatory pain
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00673-7
Anti-inflammatory activities of Waltheria indica extracts by modulating expression of IL-1B, TNF-α, TNFRII and NF-κB in human macrophages
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00658-6
Pitfalls in meta-analysis
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00606-4
Significant action of Tridax procumbens L. leaf extract on reducing the TNF-α and COX-2 gene expressions in induced inflammation site in Swiss albino mice
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00634-0
VPR-254: an inhibitor of ROR-gamma T with potential utility for the treatment of inflammatory bowel disease
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00643-z
The kinin B1 and B2 receptors and TNFR1/p55 axis on neuropathic pain in the mouse brachial plexus
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00578-5
Preemptive meloxicam achieves a better effect on postoperative pain control and similar tolerance compared with postoperative meloxicam in patients receiving arthroscopic knee surgery
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00614-4
Polygalasaponin F treats mice with pneumonia induced by influenza virus
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00633-1
Passive transfer of allergic encephalomyelitis in rats: a tool for drug mechanism studies and detecting late-acting immunosuppressants
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00565-w
Antinociceptive effect of flavonol and a few structurally related dimethoxy flavonols in mice
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00579-4
Clindamycin inhibits nociceptive response by reducing tumor necrosis factor-α and CXCL-1 production and activating opioidergic mechanisms
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00670-w
Therapeutic potential of aryl hydrocarbon receptor in autoimmunity
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00651-z
Anti-inflammatory drugs in the prevention of post-operative atrial fibrillation: a literature review
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00653-x
Benefits and risks of low molecular weight heparin in patients with acute exacerbation of chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00659-5
The intensity of joint pain in relation to changes in serum TNFα during therapy with anti-TNFα inhibitors
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00564-x
Dendritic cells generated in the presence of interferon-α and modulated with dexamethasone as a novel tolerogenic vaccine platform
来源期刊:InflammopharmacologyDOI:10.1007/s10787-019-00641-1