Frontiers in Immunology is a leading journal in its field, publishing rigorously peer-reviewed research across basic, translational and clinical immunology. Field Chief Editor Luigi Daniele Notarangelo is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.Frontiers in Immunology is the official Journal of the International Union of Immunological Societies (IUIS). Encompassing the entire field of Immunology, this journal welcomes papers that investigate basic mechanisms of immune system development and function, with a particular emphasis given to the description of the clinical and immunological phenotype of human immune disorders, and on the definition of their molecular basis.
《免疫学前沿》是该领域的领先期刊，发表了基础、转化和临床免疫学方面的严格同行评审研究。领域主编Luigi Daniele Notarangelo由一个由国际研究人员组成的杰出编辑委员会支持。这是一本多学科开放获取的期刊，在向全世界的研究人员、学者、临床医生和公众传播和交流科学知识和有影响力的发现方面处于最前沿。《免疫学前沿》是国际免疫学会联合会（IUIS）的官方期刊。本杂志涵盖整个免疫学领域，欢迎研究免疫系统发育和功能的基本机制的论文，特别强调对人类免疫疾病的临床和免疫表型的描述，以及对它们的分子基础的定义。
Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4+ and CD8+ T-Cells
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00847
Microbiome and Autoimmune Uveitis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00232
An IL-4/21 Inverted Cytokine Receptor Improving CAR-T Cell Potency in Immunosuppressive Solid-Tumor Microenvironment
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01691
Johnny on the Spot-Chronic Inflammation Is Driven by HMGB1
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01561
Prostaglanin-E2 Potentiates the Suppressive Functions of Human Mononuclear Myeloid-Derived Suppressor Cells and Increases Their Capacity to Expand IL-10-Producing Regulatory T Cell Subsets
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00475
Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01843
Glucocorticoid Receptor-Deficient Foxp3+ Regulatory T Cells Fail to Control Experimental Inflammatory Bowel Disease
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00472
Regulation of IgA Production by Intestinal Dendritic Cells and Related Cells
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01891
Immunopathogenesis of Pediatric Localized Scleroderma
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00908
The Influence of Innate Lymphoid Cells and Unconventional T Cells in Chronic Inflammatory Lung Disease
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01597
Non-classical B Cell Memory of Allergic IgE Responses
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00715
New Biomarkers for Atherothrombosis in Antiphospholipid Syndrome: Genomics and Epigenetics Approaches
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00764
Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01256
Synovial Tissue Inflammation Mediated by Autoimmune T Cells
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01989
CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2018.03135
Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02082
Transitions of CDR-L3 Loop Canonical Cluster Conformations on the Micro-to-Millisecond Timescale
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02652
GRA24-Based DNA Vaccine Prolongs Survival in Mice Challenged With a Virulent Toxoplasma gondii Strain
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00418
Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00198
CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01619
Classical and Non-classical Presentations of Complement Factor I Deficiency: Two Contrasting Cases Diagnosed via Genetic and Genomic Methods
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01150
Emerging Roles for G-protein Coupled Receptors in Development and Activation of Macrophages
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02031
AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01904
Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02130
Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00485
Microbiota Induced Changes in the Immune Response in Pregnant Mice
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02976
Distributed Adaptive Search in T Cells: Lessons From Ants
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01357
Immune-Modulation by the Human Respiratory Syncytial Virus: Focus on Dendritic Cells
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00810
NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00154
Alarmin HMGB1 and Soluble RAGE as New Tools to Evaluate the Risk Stratification in Patients With the Antiphospholipid Syndrome
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00460
Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02181
Design and Development of a Novel Peptide for Treating Intestinal Inflammation
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01841
A Combined Strategy to Improve the Development of a Coral Antivenom Against Micrurus spp.
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02422
Harnessing Dendritic Cells for Poly (D,L-lactide-co-glycolide) Microspheres (PLGA MS)—Mediated Anti-tumor Therapy
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00707
Microbial Translocation Is Linked to a Specific Immune Activation Profile in HIV-1-Infected Adults With Suppressed Viremia
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02185
Disseminated and Congenital Toxoplasmosis in a Mother and Child With Activated PI3-Kinase δ Syndrome Type 2 (APDS2): Case Report and a Literature Review of Toxoplasma Infections in Primary Immunodeficiencies
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00077
Functional Analysis of Anti-cytokine Autoantibodies Using Flow Cytometry
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01517
Early Host Interactions That Drive the Dysregulated Response in Sepsis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01748
Bone Marrow Transplantation 1957-2019
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01246
TLR3 Ligand PolyI:C Prevents Acute Pancreatitis Through the Interferon-β/Interferon-α/β Receptor Signaling Pathway in a Caerulein-Induced Pancreatitis Mouse Model
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00980
Mucosal-Associated Invariant T Cell Features and TCR Repertoire Characteristics During the Course of Multiple Sclerosis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02690
Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00459
Evolutionary Story of the Low/Medium-Affinity IgG Fc Receptor Gene Cluster
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01297
Cardiotrophin-Like Cytokine Factor 1 Exhibits a Myeloid-Biased Hematopoietic-Stimulating Function
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02133
Unveiling Integrated Functional Pathways Leading to Enhanced Respiratory Disease Associated With Inactivated Respiratory Syncytial Viral Vaccine
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00597
Immunogenicity and Safety of the M72/AS01E Candidate Vaccine Against Tuberculosis: A Meta-Analysis
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02089
Human B Cells Engage the NCK/PI3K/RAC1 Axis to Internalize Large Particles via the IgM-BCR
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.00415
The Aquaporin 5 −1364A/C Promoter Polymorphism Is Associated With Cytomegalovirus Infection Risk in Kidney Transplant Recipients
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02871
Novel Loci Controlling Parasite Load in Organs of Mice Infected With Leishmania major, Their Interactions and Sex Influence
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.01083
Disruption of the preB Cell Receptor Complex Leads to Decreased Bone Mass
来源期刊：Frontiers in ImmunologyDOI：10.3389/fimmu.2019.02063
