Stem Cell Research & Therapy is the major forum for translational research into stem cell therapies. An international peer-reviewed journal, it publishes high-quality open access research articles with a special emphasis on basic, translational and clinical research into stem cell therapeutics and regenerative therapies, including animal models and clinical trials. The journal also provides reviews, viewpoints, commentaries and reports.
干细胞研究与治疗是干细胞治疗转化研究的主要论坛。作为一份国际同行评审期刊,它发表高质量的开放获取研究文章,特别强调干细胞疗法和再生疗法的基础、转化和临床研究,包括动物模型和临床试验。该杂志还提供评论、观点、评论和报告。
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1177-1
Lineage-specific exosomes promote the odontogenic differentiation of human dental pulp stem cells (DPSCs) through TGFβ1/smads signaling pathway via transfer of microRNAs
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1278-x
MSC-secreted TGF-β regulates lipopolysaccharide-stimulated macrophage M2-like polarization via the Akt/FoxO1 pathway
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1447-y
The potential and limitations of induced pluripotent stem cells to achieve wound healing
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1185-1
Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1432-5
Low concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB signaling pathway
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1321-y
Modulating autophagy in mesenchymal stem cells effectively protects against hypoxia- or ischemia-induced injury
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1225-x
A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1202-4
The shift in the balance between osteoblastogenesis and adipogenesis of mesenchymal stem cells mediated by glucocorticoid receptor
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1498-0
Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-β
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1367-x
Elevated level of mitochondrial reactive oxygen species via fatty acid β-oxidation in cancer stem cells promotes cancer metastasis by inducing epithelial–mesenchymal transition
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1265-2
HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1279-9
Silk fibroin scaffolds seeded with Wharton’s jelly mesenchymal stem cells enhance re-epithelialization and reduce formation of scar tissue after cutaneous wound healing
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1229-6
Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1210-4
Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90rsk-CREB pathway
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1419-2
Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1219-8
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1281-2
Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1217-x
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1280-3
A preclinical study—systemic evaluation of safety on mesenchymal stem cells derived from human gingiva tissue
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1262-5
Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1138-8
The effect of type 2 diabetes mellitus and obesity on muscle progenitor cell function
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1186-0
Correction to: Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1259-0
LncRNA Neat1 mediates miR-124-induced activation of Wnt/β-catenin signaling in spinal cord neural progenitor cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1487-3
Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1205-1
The application of resveratrol to mesenchymal stromal cell-based regenerative medicine
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1412-9
Fat extract improves fat graft survival via proangiogenic, anti-apoptotic and pro-proliferative activities
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1290-1
HMGB1-modified mesenchymal stem cells attenuate radiation-induced vascular injury possibly via their high motility and facilitation of endothelial differentiation
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1197-x
Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1282-1
A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1479-3
Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1271-4
Fast Adipogenesis Tracking System (FATS)—a robust, high-throughput, automation-ready adipogenesis quantification technique
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1141-0
Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1164-6
Multi-compositional MRI evaluation of repair cartilage in knee osteoarthritis with treatment of allogeneic human adipose-derived mesenchymal progenitor cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1406-7
Human ADSC xenograft through IL-6 secretion activates M2 macrophages responsible for the repair of damaged muscle tissue
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1188-y
Deferasirox drives ROS-mediated differentiation and induces interferon-stimulated gene expression in human healthy haematopoietic stem/progenitor cells and in leukemia cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1293-y
Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1418-3
Exosomes derived from human CD34+ stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1426-3
Mesenchymal stromal cells modulate the molecular pattern of healing process in tissue-engineered urinary bladder: the microarray data
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1266-1
Tissue immune profiles supporting response to mesenchymal stromal cell therapy in acute graft-versus-host disease—a gut feeling
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1449-9
Magnesium-enriched microenvironment promotes odontogenic differentiation in human dental pulp stem cells by activating ERK/BMP2/Smads signaling
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1493-5
Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1255-4
The factors present in regenerating muscles impact bone marrow-derived mesenchymal stromal/stem cell fusion with myoblasts
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1444-1
Identification of dentinogenic cell-specific surface antigens in odontoblast-like cells derived from adult dental pulp
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1232-y
Safety and efficacy of ex vivo expanded CD34+ stem cells in murine and primate models
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1275-0
Direct action of FSH on testicular stem cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1390-y
Microtubule destabilization caused by silicate via HDAC6 activation contributes to autophagic dysfunction in bone mesenchymal stem cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1441-4
Correction to: Human umbilical cord-derived mesenchymal stem cells protect against experimental colitis via CD5+ B regulatory cells
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1132-1
A novel approach to label bone marrow-derived mesenchymal stem cells with mixed-surface PAMAM dendrimers
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1171-7
Ell3 functions as a critical decision maker at the crossroad between stem cell senescence and apoptosis
来源期刊:Stem Cell Research & TherapyDOI:10.1186/s13287-019-1137-9