BioScience Trends (Print ISSN 1881-7815, Online ISSN 1881-7823) is an international peer-reviewed journal. BioScience Trends devotes to publishing the latest and most exciting advances in scientific research. Articles cover fields of life science such as biochemistry, molecular biology, clinical research, public health, medical care system, and social science in order to encourage cooperation and exchange among scientists and clinical researchers.
《生物科学趋势》（印刷版ISSN 1881-7815，在线版ISSN 1881-7823）是一本国际同行评审期刊。《生物科学趋势》致力于发表最新、最令人兴奋的科学研究进展。文章涵盖生命科学领域，如生物化学、分子生物学、临床研究、公共卫生、医疗保健系统和社会科学，以鼓励科学家和临床研究人员之间的合作和交流。
Protective effects of metformin against osteoarthritis through upregulation of SIRT3-mediated PINK1/Parkin-dependent mitophagy in primary chondrocytes.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01263
Circular RNA profiling reveals circRNA1656 as a novel biomarker in high grade serous ovarian cancer.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01021
China has faster pace than Japan in population aging in next 25 years.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01213
Efficacy and safety of external-beam radiation therapy for hepatocellular carcinoma: An overview of current evidence according to the different target population.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01261
Programmed death ligand-1, tumor infiltrating lymphocytes and HLA expression in Chinese extrahepatic cholangiocarcinoma patients: Possible immunotherapy implications.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01003
Daucosterol induces autophagic-dependent apoptosis in prostate cancer via JNK activation.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01293
Danzhi Jiangtang Capsule ameliorates kidney injury via inhibition of the JAK-STAT signaling pathway and increased antioxidant capacity in STZ-induced diabetic nephropathy rats.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01255
Improvement in the diagnosis and treatment of T2 gallbladder carcinoma is pivotal to improvement in the overall prognosis for this disease.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01039
IL16 deficiency enhances Th1 and cytotoxic T lymphocyte response against influenza A virus infection.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01286
Cordycepin induces apoptosis in human bladder cancer T24 cells through ROS-dependent inhibition of the PI3K/Akt signaling pathway.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01214
Lab on the eye: A review of tear-based wearable devices for medical use and health management.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01178
Conserved amino acids around the DIII-DI linker region of the Newcastle disease virus fusion protein are critical for protein folding and fusion activity.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01070
Preoperative albumin-bilirubin grade combined with aspartate aminotransferase-to-platelet count ratio index predict outcomes of patients with hepatocellular carcinoma within Milan criteria after liver resection.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01088
Dioscin improves postmenopausal osteoporosis through inducing bone formation and inhibiting apoptosis in ovariectomized rats.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01186
Methanol extract of Lonicera caerulea var. emphyllocalyx fruit has antibacterial and anti-biofilm activity against Streptococcus pyogenes in vitro.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01005
On medical application of neural networks trained with various types of data.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01264
The clinical safety and efficacy of conventional transcatheter arterial chemoembolization and drug-eluting beads-transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma: A meta-analysis.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01153
IFITM3 upregulates c-myc expression to promote hepatocellular carcinoma proliferation via the ERK1/2 signalling pathway.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01289
Overshadowed prospect of programmed cell death protein-1 (PD-1) inhibitor as monotherapy for patients with advanced hepatocellular carcinoma.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01161
Preoperative evaluation of the degree of liver fibrosis based on matter-element analysis using serological indicators in patients with hepatocellular carcinoma.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01311
By regulating miR-182-5p/BCL10/CYCS, sufentanil reduces the apoptosis of umbilical cord mesenchymal stem cells caused by ropivacaine.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01291
Knockdown expression of MECR, a novel gene of mitochondrial FAS II inhibits growth and colony-formation, promotes apoptosis of hepatocelluar carcinoma cells.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01109
The combination of the preoperative albumin-bilirubin grade and the fibrosis-4 index predicts the prognosis of patients with hepatocellular carcinoma after liver resection.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01212
Challenges and advances in stem cell therapy.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01241
Progress on drug pricing negotiations in China.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01339
A review of traditional Chinese medicine for treatment of glioblastoma.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01323
Growth-promoting effects of the hydrogen-sulfide compounds produced by Desulfovibrio desulfuricans subsp. desulfuricans co-cultured with Escherichia coli (DH5α) on the growth of Entamoeba and Endolimax species isolates from swine.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01233
Overview on social security system of rare diseases in China.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01209
Laparoscopic duodenum and spleen-preserving total pancreatectomy: A novel surgical technique for pancreatic intraductal papillary mucinous neoplasms.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01271
Anti-oxidant, anti-apoptotic, anti-hypoxic and anti-inflammatory conditions induced by PTY-2 against STZ-induced stress in islets.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01181
Prevention of mother-to-child transmission (PMTCT) continues to play a vital role in the response to HIV/AIDS: Current status and future perspectives.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01009
Elevated level of miR-17 along with decreased levels of TIMP-1 and IL-6 in plasma associated with the risk of in-stent restenosis.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01274
Analysis of mutations in the FOXI1 and KCNJ10 genes in infants with a single-allele SLC26A4 mutation.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01142
Hepatitis B virus recurrence after living donor liver transplantation of anti-HBc-positive grafts: A 22-year experience at a single center.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01283
Design, synthesis and biological evaluation of 4-piperidin-4-yl-triazole derivatives as novel histone deacetylase inhibitors.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01055
Driving factors and mode transformation regarding health technology assessment (HTA) in China: Problems and recommendations.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01100
Human cytomegalovirus IE2 protein regulates macrophage-mediated immune escape by upregulating GRB2 expression in UL122 genetically modified mice.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01197
Higher ꞵ-human chorionic gonadotropin and estrogen levels during the first 6 weeks of pregnancy are associated with threatened abortion.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01111
Neuron loss and dysfunctionality in hippocampus explain aircraft noise induced working memory impairment: a resting-state fMRI study on military pilots.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01190
Treatment modalities and relative survival in patients with brain metastasis from colorectal cancer.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01044
Protection of paeonol against epirubicin-induced hepatotoxicity: A metabolomic study.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01105
The epidemic of major sexually transmitted diseases in Shanghai, China, 2009-2018.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01158
Structural analyses of a hemolytic compound found in an extract of Hypsizygus marmoreus fruiting bodies at a low pH.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01008
Combined machine learning and functional magnetic resonance imaging allows individualized prediction of high-altitude induced psychomotor impairment: The role of neural functionality in putamen and pallidum.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01002
Difference in distribution of malignant melanoma and melanocytic nevus in the palm and finger.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01221
Predictive value of some pro-oxidants in type 2 diabetes mellitus with vascular complications.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01020
New thoughts in exploring the pathogenesis, diagnosis, and treatment of threatened abortion.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01155
Prognosis for patients with hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT) after surgical treatment.
来源期刊：Bioscience trendsDOI：10.5582/bst.2018.01234
Middle-aged female rats lack changes in histone H3 acetylation in the anterior hypothalamus observed in young females on the day of a luteinizing hormone surge.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01162
MLS128 antibody-induced suppression of colon cancer cell growth is mediated by a desmocollin and a 110 kDa glycoprotein.
来源期刊：Bioscience trendsDOI：10.5582/bst.2019.01074
