Trends in Pharmacological Sciences (TIPS) is a monthly peer-reviewed reviews journal that publishes reviews and opinions in fields broadly covering pharmacology, pharmacy, pharmaceutics and toxicology. Launched in 1979, TIPS has an impact factor (IF) of 11.523 as of 2019. Every issue of TIPS contains succinct articles on the most exciting recent developments in pharmacology and therapeutics research. The major areas of research that TIPS is interested in are:Drug discovery and Development; Basic and Clinical Pharmacology; Therapeutics; Drug safety and toxicity; Pharmacy, pharmacoepidemiology and pharmacoeconomics.TIPS particularly seeks articles that are relevant to one or more of these themes. Additionally, TIPS welcomes articles on biopharma regulatory landscape, science policy and regulation and bioethics.
《 药理 学 科学 趋势 》 （ TIPS ） 是 一 份 每月 出版 的 同行 评审 期刊 ， 发表 广泛 涵盖 药理 学 、 药学 、 药剂 学 和 毒理 学 领域 的 评论 和 意见 。TIPS 于 1979 年 推出 ， 截至 2019 年 的 影响 因子 （ IF ） 为 11.523 。每 一期 TIPS 都 包含 了 关于 药理 学 和 治疗 学 研究 最 令 人 兴奋 的 最 新 进展 的 简明 文章 。TIPS 感 兴趣 的 主要 研究 领域 是 ： 药物 发现 和 开发 ;基础 与 临床 药理 学 ;治疗 学 ;药物 安全 性 和 毒性 ;药学 ， 药物 流行 病学 和 药物 经济 学 。 TIPS 特别 寻找 与 这些 主题 中 的 一 个 或 多 个 相关 的 文章 。此外 ， TIPS 欢迎 关于 生物 制药 监管 前景 、 科学 政策 和 监管 以及 生物 伦理 学 的 文章 。
Liquid Biopsies in Cancer Diagnosis, Monitoring, and Prognosis.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.01.006
Artificial Intelligence for Clinical Trial Design.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.05.005
Triptolide and Its Derivatives as Cancer Therapies.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.03.002
MDSC; the Most Important Cell You Have Never Heard Of.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.10.008
Advancing Drug Discovery via Artificial Intelligence.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.06.004
Targeting SOCS Proteins to Control JAK-STAT Signalling in Disease.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.03.001
Patterns of Genomic Instability in Breast Cancer.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.01.005
The Molecular Function of σ Receptors: Past, Present, and Future.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.006
Toxicogenomics: A 2020 Vision.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/J.TIPS.2018.12.001
Small Molecules to Improve ER Proteostasis in Disease.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.003
Building Biological Shields via Hormesis.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.10.010
Artificial Intelligence for Drug Toxicity and Safety.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.005
Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome
来源期刊：Trends in Pharmacological SciencesDOI：10.1016/j.tips.2018.12.003
New Frontiers in Lp(a)-Targeted Therapies.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.01.004
Targeting the Oxytocin System: New Pharmacotherapeutic Approaches.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.11.001
Deep Aging Clocks: The Emergence of AI-Based Biomarkers of Aging and Longevity.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.05.004
Preserving the CTLA-4 Checkpoint for Safer and More Effective Cancer Immunotherapy.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.11.003
Strategies for the CRISPR-Based Therapeutics.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.11.006
Nature-Derived Peptides: A Growing Niche for GPCR Ligand Discovery.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.03.004
Lysosomal Acid Lipase: From Cellular Lipid Handler to Immunometabolic Target.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.12.006
Thiol-Based Drugs in Pulmonary Medicine: Much More than Mucolytics.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.04.015
Artificial Intelligence: A Novel Approach for Drug Discovery.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.06.005
Current Landscape of Treatments for Wolfram Syndrome.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.011
ABHD6: Its Place in Endocannabinoid Signaling and Beyond.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.02.002
Emerging Structure-Function Paradigm of Endocrine FGFs in Metabolic Diseases.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.12.002
Targeting TRP Channels - Valuable Alternatives to Combat Pain, Lower Urinary Tract Disorders, and Type 2 Diabetes?
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.004
Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.09.003
Pharmacological and Molecular Mechanisms Behind the Sterilizing Activity of Pyrazinamide.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.10.005
Alport Syndrome Therapeutics: Ready for Prime-Time Players.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.012
Phosphodiesterase Type 4 Inhibition in CNS Diseases.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.10.006
Why Are Some Driver Mutations Rare?
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.10.003
Artificial Intelligence for Pharma: Time for Internal Investment.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.05.003
Can Adding Constitutive Receptor Activity Redefine Biased Signaling Quantification?
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.01.002
Potential of Epigenetic Therapy for Prader-Willi Syndrome.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.002
Unexpected Synergy Reveals New Therapeutic Strategy in SCLC.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.03.005
Has Drug Design Augmented by Artificial Intelligence Become a Reality?
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.09.004
A Coordinated Attack: Rett Syndrome Therapeutic Development.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.02.007
Pharmacological Modulation of Transcriptional Coregulators in Cancer.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.04.004
Affordable Preeclampsia Therapeutics.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2018.12.007
Overcoming the Brain Barriers: From Immune Cells to Nanoparticles.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.11.001
Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.10.001
Opportunities for Electroceuticals in Epilepsy.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.08.001
The Sodium Channel Voltage Sensor Slides to Rest.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.08.009
Deep Learning to Therapeutically Target Unreported Complexes.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.04.009
Max-imizing the Attenuation of Myc Using Small Molecules.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.06.002
Targeting Non-coding RNA Sensitizes Cancer Cells to Drugs.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.04.017
Dismantling a Toxin to Disarm a Superbug.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.01.007
Targeting Mutant KRAS for Immunogenic Cell Death Induction.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.11.004
Substrate-Selective Enzyme Inhibitors.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.07.009
Computational Approaches to Anesthetic Drug Discovery.
来源期刊：Trends in pharmacological sciencesDOI：10.1016/j.tips.2019.09.001
