Archives of Toxicology provides up-to-date information on the latest advances in toxicology. The journal places particular emphasis on studies relating to defined effects of chemicals and mechanisms of toxicity, including toxic activities at the molecular level, in humans and experimental animals. Coverage includes new insights into analysis and toxicokinetics and into forensic toxicology. Review articles of general interest to toxicologists are an additional important feature of the journal.
毒理学档案提供毒理学最新进展的最新信息。该杂志特别强调与化学品的明确影响和毒性机制有关的研究，包括在人类和实验动物中分子水平上的毒性活动。报道内容包括对分析和毒代动力学以及法医毒理学的新见解。毒理学家普遍感兴趣的综述文章是该杂志的另一个重要特色。
Emerging and established modes of cell death during acetaminophen-induced liver injury
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02597-1
Ecdysteroids as non-conventional anabolic agent: performance enhancement by ecdysterone supplementation in humans
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02490-x
Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02406-9
Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02471-0
Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02565-9
The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02539-x
A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02462-1
Aggregated aluminium exposure: risk assessment for the general population
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02599-z
Particulate matter 2.5 induced arrhythmogenesis mediated by TRPC3 in human induced pluripotent stem cell-derived cardiomyocytes
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02403-y
Multispecies study: low-dose tributyltin impairs ovarian theca cell cholesterol homeostasis through the RXR pathway in five mammalian species including humans
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02449-y
Behavioural and metabolomic changes from chronic dietary exposure to low-level deoxynivalenol reveal impact on mouse well-being
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02470-1
A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02440-7
Minor structural modifications of bisphenol A strongly affect physiological responses of HepG2 cells
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02457-y
Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02579-3
Sirt3 promotes sensitivity to sunitinib-induced cardiotoxicity via inhibition of GTSP1/JNK/autophagy pathway in vivo and in vitro
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02573-9
Case study: Is bisphenol S safer than bisphenol A in thermal papers?
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02474-x
Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02602-7
Genome-wide somatic mutation analysis via Hawk-Seq™ reveals mutation profiles associated with chemical mutagens
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02541-3
Beta-ionone-inhibited proliferation of breast cancer cells by inhibited COX-2 activity
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02550-2
Measurement of urinary arsenic profiles and DNA hypomethylation in a case–control study of urothelial carcinoma
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02500-y
Identification of glycyrrhizin metabolites in humans and of a potential biomarker of liquorice-induced pseudoaldosteronism: a multi-centre cross-sectional study
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02588-2
Integration of epidemiological findings with mechanistic evidence in regulatory pesticide risk assessment: EFSA experiences
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02467-w
Upregulation of let-7f-2-3p by long noncoding RNA NEAT1 inhibits XPO1-mediated HAX-1 nuclear export in both in vitro and in vivo rodent models of doxorubicin-induced cardiotoxicity
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02586-4
Biomonitoring of nutritional acrylamide intake by consumers without dietary preferences as compared to vegans
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02412-x
Technological advancements for the development of stem cell-based models for hepatotoxicity testing
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02465-y
Okadaic acid activates Wnt/β-catenin-signaling in human HepaRG cells
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02489-4
Time-resolved characterization of the mechanisms of toxicity induced by silica and amino-modified polystyrene on alveolar-like macrophages
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02604-5
Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02606-3
Integrating physiologically based kinetic (PBK) and Monte Carlo modelling to predict inter-individual and inter-ethnic variation in bioactivation and liver toxicity of lasiocarpine.
来源期刊：Archives of toxicologyDOI：10.1007/s00204-019-02563-x
Comment on ‘Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats’, Arch Toxicol 92:2629–2643
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02386-w
In vivo evaluation of the effect of arsenite on the intestinal epithelium and associated microbiota in mice
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02510-w
Naturally occurring bisphenol F in plants used in traditional medicine
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02442-5
Gene co-regulation and co-expression in the aryl hydrocarbon receptor-mediated transcriptional regulatory network in the mouse liver
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02620-5
1-Methoxy-3-indolylmethyl DNA adducts in six tissues, and blood protein adducts, in mice under pak choi diet: time course and persistence
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02452-3
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02486-7
Comparisons of statistical models for growth curves from 90-day rat feeding studies
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02496-5
Mild steel welding is associated with alterations in circulating levels of cancer-related proteins
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02594-4
Tattooing: overriding the skin barrier and the journey into the unknown
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02646-9
Effects of arsenic exposure on d-serine metabolism in the hippocampus of offspring mice at different developmental stages
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02616-1
Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02638-9
Investigation of age-related differences in toxicokinetic processes of deoxynivalenol and deoxynivalenol-3-glucoside in weaned piglets
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02644-x
Satirical contributions in toxicology
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02482-x
Correction to: Human skin-derived ABCB5+ stem cell injection improves liver disease parameters in Mdr2KO mice
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02603-6
Acetaminophen induces programmed necrosis
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02625-0
Toxicokinetics of N-ethyl-2-pyrrolidone and its metabolites in blood, urine and amniotic fluid of rats after oral administration
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02404-x
Highlight report: caspase 8 as a therapeutic target in chronic liver disease
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02535-1
Mechanistic examination of methimazole-induced hepatotoxicity in patients with Grave’s disease: a metabolomic approach
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02618-z
Metabolism and genotoxicity of polycyclic aromatic hydrocarbons in human skin explants: mixture effects and modulation by sunlight
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02650-z
Dietary exposure to chlorpyrifos inhibits the polarization of regulatory T cells in C57BL/6 mice with dextran sulfate sodium-induced colitis
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02615-2
Identification of interactions of binary variables associated with survival time using survivalFS
来源期刊：Archives of ToxicologyDOI：10.1007/s00204-019-02398-6
