eLife publishes work of the highest scientific standards and importance in all areas of the life and biomedical sciences. The research is selected and evaluated by working scientists and is made freely available to all readers without delay. eLife also invests in innovation through open-source tool development to accelerate research communication and discovery. Our work is guided by the communities we serve.
eLife出版生命和生物医学科学所有领域的最高科学标准和重要性的作品。这项研究是由工作的科学家选择和评估，并免费提供给所有读者没有延误。eLife还通过开源工具开发投资于创新，以加速研究交流和发现。我们的工作以我们所服务的社区为指导。
Reduced signal for polygenic adaptation of height in UK Biobank
来源期刊：eLifeDOI：10.7554/eLife.39725
The human coronavirus HCoV-229E S-protein structure and receptor binding
来源期刊：eLifeDOI：10.7554/eLife.51230
Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor–ligand complex
来源期刊：eLifeDOI：10.7554/eLife.48630
Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses
来源期刊：eLifeDOI：10.7554/eLife.43983
Independent amylase gene copy number bursts correlate with dietary preferences in mammals
来源期刊：eLifeDOI：10.7554/eLife.44628
A generalized theory of age-dependent carcinogenesis
来源期刊：eLifeDOI：10.7554/eLife.39950
Profiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries
来源期刊：eLifeDOI：10.7554/eLife.46615
Pretectal neurons control hunting behaviour
来源期刊：eLifeDOI：10.7554/eLife.48114
Context-dependent signaling of coincident auditory and visual events in primary visual cortex
来源期刊：eLifeDOI：10.7554/eLife.44006
The dynamic conformational landscape of the protein methyltransferase SETD8
来源期刊：eLifeDOI：10.7554/eLife.45403
TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections
来源期刊：eLifeDOI：10.7554/eLife.46997
Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
来源期刊：eLifeDOI：10.7554/eLife.45829
Apicomplexan-like parasites are polyphyletic and widely but selectively dependent on cryptic plastid organelles
来源期刊：eLifeDOI：10.7554/eLife.49662
The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats
来源期刊：eLifeDOI：10.7554/eLife.49041
The follicle epithelium in the Drosophila ovary is maintained by a small number of stem cells
来源期刊：eLifeDOI：10.7554/eLife.49050
TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization
来源期刊：eLifeDOI：10.7554/eLife.38949
Network-wide abnormalities explain memory variability in hippocampal amnesia
来源期刊：eLifeDOI：10.7554/eLife.46156
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome
来源期刊：eLifeDOI：10.7554/eLife.48828
Ribosome biogenesis restricts innate immune responses to virus infection and DNA
来源期刊：eLifeDOI：10.7554/eLife.49551
A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation
来源期刊：eLifeDOI：10.7554/eLife.41768
A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity
来源期刊：eLifeDOI：10.7554/eLife.45393
Subcellular drug targeting illuminates local kinase action
来源期刊：eLifeDOI：10.7554/eLife.52220
Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations
来源期刊：eLifeDOI：10.7554/eLife.50465
Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway
来源期刊：eLifeDOI：10.7554/eLife.48165
The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi’s sarcoma-associated herpesvirus
来源期刊：eLifeDOI：10.7554/eLife.47261
Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
来源期刊：eLifeDOI：10.7554/eLife.41461
Mitochondrial fusion is required for spermatogonial differentiation and meiosis
来源期刊：eLifeDOI：10.7554/eLife.51601
Atypical memory B-cells are associated with Plasmodium falciparum anemia through anti-phosphatidylserine antibodies
来源期刊：eLifeDOI：10.7554/eLife.48309
Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt
来源期刊：eLifeDOI：10.7554/eLife.45631
Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion
来源期刊：eLifeDOI：10.7554/eLife.47209
Decoupling sensory from decisional choice biases in perceptual decision making
来源期刊：eLifeDOI：10.7554/eLife.43994
Liquid-crystal organization of liver tissue
来源期刊：eLifeDOI：10.7554/eLife.44860
Perception in autism does not adhere to Weber’s law
来源期刊：eLifeDOI：10.7554/eLife.42223
Impact of seasonal variations in Plasmodium falciparum malaria transmission on the surveillance of pfhrp2 gene deletions
来源期刊：eLifeDOI：10.7554/eLife.40339
Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle
来源期刊：eLifeDOI：10.7554/eLife.39777
Regulation of subcellular dendritic synapse specificity by axon guidance cues
来源期刊：eLifeDOI：10.7554/eLife.43478
Demographic reconstruction from ancient DNA supports rapid extinction of the great auk
来源期刊：eLifeDOI：10.7554/eLife.47509
Entrained neuronal activity to periodic visual stimuli in the primate striatum compared with the cerebellum
来源期刊：eLifeDOI：10.7554/eLife.48702
PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice
来源期刊：eLifeDOI：10.7554/eLife.45961
Different genetic mechanisms mediate spontaneous versus UVR-induced malignant melanoma
来源期刊：eLifeDOI：10.7554/eLife.42424
Velocity coupling of grid cell modules enables stable embedding of a low dimensional variable in a high dimensional neural attractor
来源期刊：eLifeDOI：10.7554/eLife.48494
Transitions in cell potency during early mouse development are driven by Notch
来源期刊：eLifeDOI：10.7554/ELIFE.42930
Monkey EEG links neuronal color and motion information across species and scales
来源期刊：eLifeDOI：10.7554/eLife.45645
Extrinsic and intrinsic dynamics in movement intermittency
来源期刊：eLifeDOI：10.7554/eLife.40145
Adapting for life in the extreme
来源期刊：eLifeDOI：10.7554/eLife.48999
Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice
来源期刊：eLifeDOI：10.7554/eLife.50712
A lesson in homology
来源期刊：eLifeDOI：10.7554/eLife.48335
Down but not out
来源期刊：eLifeDOI：10.7554/eLife.53363
Learning from ancestors
来源期刊：eLifeDOI：10.7554/eLife.49976
MicroRNA-mediated control of developmental lymphangiogenesis
来源期刊：eLifeDOI：10.7554/eLife.46007
