Nature Structural & Molecular Biology is an integrated forum for structural and molecular studies. The journal places a strong emphasis on functional and mechanistic understanding of how molecular components in a biological process work together. Structural data may provide such insights, but they are not a pre-requisite for publication in the journal.
自然结构与分子生物学是一个结构和分子研究的综合论坛。该杂志非常强调对生物过程中分子成分如何协同工作的功能和机制的理解。结构数据可能会提供这样的见解，但它们不是在杂志上发表的先决条件。
An anti-CRISPR protein disables type V Cas12a by acetylation
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0206-1
Broad-spectrum enzymatic inhibition of CRISPR-Cas12a
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0208-z
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0197-y
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0323-x
Atg2 mediates direct lipid transfer between membranes for autophagosome formation.
来源期刊：Nature Structural & Molecular BiologyDOI：10.2210/PDB6A9J/PDB
Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0322-y
Xist RNA antagonizes the SWI/SNF chromatin remodeler BRG1 on the inactive X chromosome
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-018-0176-8
Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0305-z
Structural snapshots of actively transcribing influenza polymerase
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0232-z
Structural basis of tubulin detyrosination by the vasohibin–SVBP enzyme complex
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0241-y
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0227-9
Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0246-6
Apn2 Resolves Blocked 3’ Ends and Suppresses Top1-Induced Mutagenesis at Genomic rNMP Sites.
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0186-1
Structure of a P element transposase–DNA complex reveals unusual DNA structures and GTP-DNA contacts
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0319-6
An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0308-9
A symmetric toggle switch explains the onset of random X inactivation in different mammals
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0214-1
Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0326-7
Torque transmission mechanism of the curved bacterial flagellar hook revealed by cryo-EM
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0301-3
X-chromosome upregulation is driven by increased burst frequency
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0306-y
Transcription preinitiation complex structure and dynamics provide insight into genetic diseases
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0220-3
Cryo-EM structure of the ClpXP protein degradation machinery
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0304-0
Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
来源期刊：Nature Structural & Molecular BiologyDOI：10.2210/PDB6O9M/PDB
Nascent-protein ubiquitination is required for heat shock–induced gene downregulation in human cells
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-018-0182-x
A systems view of spliceosomal assembly and branchpoints with iCLIP
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0300-4
The peptide hormone glucagon forms amyloid fibrils with two coexisting beta-strand conformations.
来源期刊：Nature Structural & Molecular BiologyDOI：10.2210/PDB6NZN/PDB
Structural basis of tubulin detyrosination by vasohibins
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0242-x
Structures of human ENT1 in complex with adenosine reuptake inhibitors
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0245-7
Structural snapshots of actively transcribing influenza polymerase.
来源期刊：Nature Structural & Molecular BiologyDOI：10.2210/PDB6QCT/PDB
Ten catalytic snapshots of rhomboid intramembrane proteolysis from gate opening to peptide release
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0296-9
The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0238-6
Enzymatic anti-CRISPRs improve the bacteriophage arsenal
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0210-5
Molecular mechanism of cotranslational membrane protein recognition and targeting by SecA
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0297-8
Tracking RNA structures as RNAs transit through the cell
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0213-2
FACT mediates cohesin function on chromatin
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0307-x
Aaron Klug (1926–2018)
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-018-0183-9
Neutral epigenetic inheritance: being prepared for future generations
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0239-5
Structure of the P element transpososome reveals new twists on the DD(E/D) theme
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0329-4
Twist to disentangle
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0209-y
Dynein tails: how to hitch a ride on an IFT train
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0285-z
Capturing genome folds in single sensory neurons
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0212-3
Author Correction: The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0295-x
An RNA exporter that enforces a no-export policy
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0294-y
Hooked on motility
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0302-2
Publisher Correction: Five decades of eukaryotic transcription
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0338-3
Michael Rossmann, data-sharing champion
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0282-2
Cryo-EM Structures of Four Polymorphic TDP-43 Amyloid Cores
来源期刊：Nature structural & molecular biologyDOI：10.1038/s41594-019-0248-4
Joseph F. Sambrook (1939–2019)
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0311-1
Author Correction: G-tract RNA removes Polycomb repressive complex 2 from genes
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0341-8
Reoviridae transcription is more than an open-and-shut case
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0328-5
Outlining the proton-conduction pathway in otopetrin channels
来源期刊：Nature Structural & Molecular BiologyDOI：10.1038/s41594-019-0260-8
