The Official Journal of the International Society for Cellular OncologyFocuses on translational researchAddresses the conversion of cell biology to clinical applicationsCellular Oncology publishes scientific contributions from various biomedical and clinical disciplines involved in basic and translational cancer research on the cell and tissue level, technical and bioinformatics developments in this area, and clinical applications. This includes a variety of fields like genome technology, micro-arrays and other high-throughput techniques, genomic instability, SNP, DNA methylation, signaling pathways, DNA organization, (sub)microscopic imaging, proteomics, bioinformatics, functional effects of genomics, drug design and development, molecular diagnostics and targeted cancer therapies, genotype-phenotype interactions. A major goal is to translate the latest developments in these fields from the research laboratory into routine patient management. To this end Cellular Oncology forms a platform of scientific information exchange between molecular biologists and geneticists, technical developers, pathologists, (medical) oncologists and other clinicians involved in the management of cancer patients.In vitro studies are preferentially supported by validations in tumor tissue with clinicopathological associations.
国际细胞肿瘤学会官方期刊专注于转化研究解决细胞生物学向临床应用的转化细胞肿瘤学发表来自不同生物医学和临床学科的科学论文，涉及细胞和组织水平的基础和转化癌症研究、该领域的技术和生物信息学发展以及临床应用。这包括许多领域，如基因组技术、微阵列和其他高通量技术、基因组不稳定性、SNP、DNA甲基化、信号通路、DNA组织、（亚）显微成像、蛋白质组学、生物信息学、基因组学的功能效应、药物设计和开发、分子诊断和靶向癌症治疗、基因型-表型相互作用。一个主要目标是将这些领域的最新发展从研究实验室转化为常规患者管理。为此，细胞肿瘤学在分子生物学家、遗传学家、技术开发人员、病理学家、（医学）肿瘤学家和其他参与癌症患者管理的临床医生之间形成了一个科学信息交流的平台。体外研究优先得到具有临床病理学相关性的肿瘤组织验证的支持。
Tumor-associated macrophages: role in cancer development and therapeutic implications
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00453-z
Leptin-induced signaling pathways in cancer cell migration and invasion
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00428-0
The emerging role of noncoding RNAs in colorectal cancer chemoresistance
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00466-8
Exosomes derived from cancer stem cells of gemcitabine-resistant pancreatic cancer cells enhance drug resistance by delivering miR-210
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00476-6
Computer aided quantification of intratumoral stroma yields an independent prognosticator in rectal cancer
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00429-z
SNHG6 is upregulated in primary breast cancers and promotes cell cycle progression in breast cancer-derived cell lines
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00422-6
Curcumin: a potent agent to reverse epithelial-to-mesenchymal transition
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00442-2
Notch pathway in small-cell lung cancer: from preclinical evidence to therapeutic challenges
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00441-3
Analysis of functional hub genes identifies CDC45 as an oncogene in non-small cell lung cancer - a short report
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00438-y
Esophageal carcinoma: Towards targeted therapies
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00488-2
CD47: role in the immune system and application to cancer therapy
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00469-5
The therapeutic potential of mesenchymal stem cells in lung cancer: benefits, risks and challenges
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00459-7
Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00455-x
Clinical and biological impact of miR-18a expression in breast cancer after neoadjuvant chemotherapy
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00450-2
A positive feedback loop involving the LINC00346/β-catenin/MYC axis promotes hepatocellular carcinoma development
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00478-4
Human bone marrow-derived mesenchymal stem cell-secreted exosomes overexpressing microRNA-34a ameliorate glioblastoma development via down-regulating MYCN
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00461-z
Deep learning and manual assessment show that the absolute mitotic count does not contain prognostic information in triple negative breast cancer
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00445-z
Tumor dormancy as an alternative step in the development of chemoresistance and metastasis - clinical implications
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00467-7
Inhibition of CBP/β-catenin and porcupine attenuates Wnt signaling and induces apoptosis in head and neck carcinoma cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00440-4
Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00446-y
HMGB1: an overview of its versatile roles in the pathogenesis of colorectal cancer
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00477-5
Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00471-x
CDK7 inhibition as a promising therapeutic strategy for lung squamous cell carcinomas with a SOX2 amplification
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00434-2
Recombinant cell-permeable HOXA9 protein inhibits NSCLC cell migration and invasion
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00424-4
The role of caveolin-1 in tumors of the brain - functional and clinical implications
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00447-x
Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00451-1
Interplay between HSF1 and p53 signaling pathways in cancer initiation and progression: non-oncogene and oncogene addiction
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00452-0
PRMT1 promotes pancreatic cancer growth and predicts poor prognosis
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00435-1
Multiple novel hepatocellular carcinoma signature genes are commonly controlled by the master pluripotency factor OCT4
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00487-3
MicroRNA-129-5p suppresses nasopharyngeal carcinoma lymphangiogenesis and lymph node metastasis by targeting ZIC2
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00485-5
Inhibition of MEK suppresses hepatocellular carcinoma growth through independent MYC and BIM regulation
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00432-4
Prognostic and therapeutic significance of circulating tumor cells in patients with lung cancer
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00470-y
The role of TNF-α in chordoma progression and inflammatory pathways
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00454-y
Mechanism of lung adenocarcinoma spine metastasis induced by CXCL17
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00491-7
Hypo-phosphorylated CD147 promotes migration and invasion of hepatocellular carcinoma cells and predicts a poor prognosis
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00444-0
Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00475-7
The Xc− inhibitor sulfasalazine improves the anti-cancer effect of pharmacological vitamin C in prostate cancer cells via a glutathione-dependent mechanism
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00474-8
CD147 augmented monocarboxylate transporter-1/4 expression through modulation of the Akt-FoxO3-NF-κB pathway promotes cholangiocarcinoma migration and invasion
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00479-3
ABT-263 exhibits apoptosis-inducing potential in oral cancer cells by targeting C/EBP-homologous protein
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00431-5
Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00425-3
Anti-tumor activity of cediranib, a pan-vascular endothelial growth factor receptor inhibitor, in pancreatic ductal adenocarcinoma cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00473-9
Prognostic value of low CDX2 expression in colorectal cancers with a high stromal content – a short report
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00436-0
Endocrine resistant breast cancer cells with loss of ERα expression retain proliferative ability by reducing caspase7-mediated HDAC3 cleavage
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00439-x
Author Correction: PRMT1 promotes pancreatic cancer growth and predicts poor prognosis
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00480-w
Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00468-6
Antitumor effect of XCT790, an ERRα inverse agonist, on ERα-negative endometrial cancer cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00423-5
The X-linked inhibitor of apoptosis protein (XIAP) is involved in melanoma invasion by regulating cell migration and survival
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00427-1
Stromal organization as predictive biomarker for the treatment of colon cancer with adjuvant bevacizumab; a post-hoc analysis of the AVANT trial
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00449-9
Author Correction: The therapeutic potential of mesenchymal stem cells in lung cancer: benefits, risks and challenges
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00483-7
The tumor suppressor FOXO3a mediates the response to EGFR inhibition in glioblastoma cells
来源期刊：Cellular OncologyDOI：10.1007/s13402-019-00443-1
