Archiv der Pharmazie - Chemistry in Life Sciences is an international journal devoted to research and development in all fields of pharmaceutical and medicinal chemistry. Emphasis is put on papers combining synthetic organic chemistry, structural biology, molecular modelling, bioorganic chemistry, natural products chemistry, biochemistry or analytical methods with pharmaceutical or medicinal aspects such as biological activity. The focus of this journal is put on original research papers, but other scientifically valuable contributions (e.g. reviews, minireviews, highlights, symposia contributions, discussions, and essays) are also welcome.
Archiv der Pharmazie - Chemistry in Life Sciences是一份致力于药物和药物化学所有领域研究和开发的国际期刊。重点放在将合成有机化学、结构生物学、分子建模、生物有机化学、天然产物化学、生物化学或分析方法与药学或医学方面(如生物活性)相结合的论文上。本期刊的重点是原创研究论文,但也欢迎其他有科学价值的贡献(如综述、小型综述、亮点、专题讨论会贡献、讨论和论文)。
Aminopyrazole‐substituted metallophthalocyanines: Preparation, aggregation behavior, and investigation of metabolic enzymes inhibition properties
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800292
Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl‐based 4‐thiazolidinone derivatives
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900304
Synthesis and antimicrobial activity of novel 1,2,3‐triazole‐conjugates of quinazolin‐4‐ones
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800302
Interconnection of sulfides and sulfoxides in medicinal chemistry
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800248
Quinolone derivatives: Potential anti‐HIV agent—development and application
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900045
New 2,4‐disubstituted‐2‐thiopyrimidines as VEGFR‐2 inhibitors: Design, synthesis, and biological evaluation
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900089
Synthesis and biological evaluation of novel benzo[c]acridine‐diones as potential anticancer agents and tubulin polymerization inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800307
Design, synthesis, biological evaluation, and molecular modeling studies of rhodanine derivatives as pancreatic lipase inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900029
Novel quinoline derivatives carrying nitrones/oximes nitric oxide donors: Design, synthesis, antiproliferative and caspase‐3 activation activities
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800270
Artemisinin‐derived dimers as potential anticancer agents: Current developments, action mechanisms, and structure–activity relationships
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900240
Design, synthesis, and biological evaluation of new pyrazino[1,2‐a]benzimidazole derivatives as selective cyclooxygenase (COX‐2) inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800265
Design and synthesis of 1,2,4‐triazolo[1,5‐a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900002
Synthesis and anti‐coronavirus activity of a series of 1‐thia‐4‐azaspiro[4.5]decan‐3‐one derivatives
来源期刊:Archiv Der PharmazieDOI:10.1002/ardp.201800330
1H‐1,2,3‐Triazole tethered isatin‐moxifloxacin: Design, synthesis and in vitro anti‐mycobacterial evaluation
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900040
Synthesis of novel gefitinib‐based derivatives and their anticancer activity
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800381
Pharmacological explorations of eco‐friendly amide substituted (Z)‐β‐enaminones as anti‐breast cancer drugs
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800244
Safran
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.18782120438
Synthesis and biological evaluation of sphingosine kinase 2 inhibitors with anti‐inflammatory activity
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800298
Identification of dehydroxy isoquine and isotebuquine as promising antileishmanial agents
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800281
1,2,4‐Triazole‐conjugated 1,3,4‐thiadiazole hybrid scaffolds: A potent ameliorant of carrageenan‐induced inflammation by lessening proinflammatory mediators
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900233
Densely substituted piperidines as a new class of elastase inhibitors: Synthesis and molecular modeling studies
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900061
Identification of new NIK inhibitors by discriminatory analysis‐based molecular docking and biological evaluation
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800374
Synthesis, molecular docking studies, and biological evaluation of novel alkyl bis(4‐amino‐5‐cyanopyrimidine) derivatives
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900027
Discovery to solve multidrug resistance: Design, synthesis, and biological evaluation of novel agents
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900127
Microwave‐assisted synthesis of 1‐substituted‐1H‐benzimidazolium salts: Non‐competitive inhibition of human carbonic anhydrase I and II
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800325
Antileismanial activity, mechanism of action study and molecular docking of 1,4‐bis(substituted benzalhydrazino)phthalazines
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800299
Novel calcitriol analogue with an oxolane group: In vitro, in vivo, and in silico studies
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800315
Design, synthesis, and molecular docking studies of novel pyrazolyl 2‐aminopyrimidine derivatives as HSP90 inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900063
Efficient synthesis of meso‐substituted porphyrins and molecular docking as potential new antioxidant and cytotoxicity agents
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800221
Synthesis, antibacterial evaluation, and DNA gyrase inhibition profile of some new quinoline hybrids
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900086
Chemical structure modifications and nano‐technology applications for improving ADME‐Tox properties, a review
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800213
Enantioselective synthesis and biological investigation of tetrahydro‐β‐carboline‐based HDAC6 inhibitors with improved solubility
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900026
G protein‐coupled receptor binding and pharmacological evaluation of indole‐derived thiourea compounds
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900218
Design, synthesis and biological evaluation of 6‐substituted quinolines derived from cabozantinib as c‐Met inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900101
Synthesis and antiageing properties of antioxidant pseudopeptides designed based on the bioisostere principle
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800354
Quinolone derivatives and their antifungal activities: An overview
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800382
Novel N‐(1‐thia‐4‐azaspiro[4.5]decan‐4‐yl)carboxamide derivatives as potent and selective influenza virus fusion inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900028
Synthesis, docking studies, and pharmacological evaluation of 5HT2C ligands containing the N′‐cyanoisonicotinamidine or N′‐cyanopicolinamidine nucleus
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800373
Bi‐heterocyclic benzamides as alkaline phosphatase inhibitors: Mechanistic comprehensions through kinetics and computational approaches
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800278
Novel ketoprofen–antioxidants mutual codrugs as safer nonsteroidal anti‐inflammatory drugs: Synthesis, kinetic and pharmacological evaluation
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800339
Synthesis and mycobacterial evaluation of 5‐substituted‐6‐acetyl‐2‐amino‐7‐methyl‐5,8‐dihydropyrido‐[2,3‐d]pyrimidin‐4(3H)‐one derivatives
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900068
Design and synthesis of imidazolidinone derivatives as potent anti‐leishmanial agents by bioisosterism
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800290
Discovery and biological evaluation of novel G protein‐coupled receptor 119 agonists for type 2 diabetes
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800267
Exploration of the structure–activity relationship and druggability of novel oxazolidinone‐based compounds as Gram‐negative antibacterial agents
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900129
Sulfonylpiperazines based on a flavone as antioxidant and cytotoxic agents
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900051
Synthesis and biological evaluation of heteroalicyclic cyanoguanidines at histamine receptors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900107
Bioassay of ferulic acid derivatives as influenza neuraminidase inhibitors
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900174
Identification of novel selective Mtb‐DHFR inhibitors as antitubercular agents through structure‐based computational techniques
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201900287
Jod.
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.18270210339
Targeting HIV‐TB coinfection by developing novel piperidin‐4‐substituted imines: Design, synthesis, in vitro and in silico studies
来源期刊:Archiv der PharmazieDOI:10.1002/ardp.201800358