Veterinary and Comparative Oncology (VCO) is an international, peer-reviewed journal integrating clinical and scientific information from a variety of related disciplines and from worldwide sources for all veterinary oncologists and cancer researchers concerned with aetiology, diagnosis and clinical course of cancer in domestic animals and its prevention. With the ultimate aim of diminishing suffering from cancer, the journal supports the transfer of knowledge in all aspects of veterinary oncology, from the application of new laboratory technology to cancer prevention, early detection, diagnosis and therapy. In addition to original articles, the journal publishes solicited editorials, review articles, commentary, correspondence and abstracts from the published literature. Accordingly, studies describing laboratory work performed exclusively in purpose-bred domestic animals (e.g. dogs, cats, horses) will not be considered.
《兽医和比较肿瘤学》（Veterinary and Comparative Oncology，VCO）是一本国际性同行评审期刊，整合了来自多个相关学科和全球来源的临床和科学信息，面向所有关注家畜癌症病因学、诊断和临床过程及其预防的兽医肿瘤学家和癌症研究人员。以减少癌症痛苦为最终目标，该杂志支持兽医肿瘤学各个方面的知识转移，从新实验室技术的应用到癌症预防，早期检测，诊断和治疗。除了原创文章外，该杂志还发表征集的社论、综述文章、评论、通信和已发表文献的摘要。因此，将不考虑描述专门在目的育种家畜（例如犬、猫、马）中进行的实验室工作的研究。
Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12459
Adjuvant anthracycline-based versus metronomic chemotherapy versus no medical treatment for dogs with metastatic splenic hemangiosarcoma: a multi-institutional retrospective study of the Italian Society of Veterinary Oncology.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12519
Immune dysregulation and Osteosarcoma: Staphylococcus aureus downregulates TGF-β and heightens the inflammatory signature in human and canine macrophages suppressed by osteosarcoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12529
Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12520
Prospective evaluation of flow cytometric characteristics, histopathologic diagnosis and clinical outcome in dogs with naïve B-cell lymphoma treated with a 19-week CHOP protocol.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12553
Anti-tumour activity of oncolytic reovirus against canine histiocytic sarcoma cells.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12468
Outcome and failure patterns of localized sinonasal lymphoma in cats treated with first-line single-modality radiation therapy: a retrospective study.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12517
Developing and testing prognostic bio-scoring systems for canine mammary gland carcinomas.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12509
Outcomes and prognostic variables associated with primary abdominal visceral soft tissue sarcomas in dogs: A Veterinary Society of Surgical Oncology retrospective study.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12456
In vitro effects of the activity of novel platinum (II) complex in canine and human cell lines.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12511
Canine CD4+ T-cell lymphoma identified by flow cytometry exhibits a consistent histomorphology and gene expression profile.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12460
Electrochemotherapy in treatment of canine oral non-tonsillar squamous cell carcinoma. a case series report.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12530
Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12455
Limb-sparing in dogs using patient-specific, 3 dimensional-printed endoprosthesis for distal radial osteosarcoma: a pilot study.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12515
Extracellular cyclic adenosine monophosphate‐dependent protein kinase A autoantibody and C‐reactive protein as serum biomarkers for diagnosis of cancer in dogs
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12450
Prognostic and Predictive Significance of KIT Protein Expression and c-kit Gene Mutation in Canine Cutaneous Mast Cell Tumours: A Consensus of the Oncology-Pathology Working Group.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12518
Canine histiocytic sarcoma cell lines with SHP2 p.Glu76Gln or p.Glu76Ala mutations are sensitive to allosteric SHP2 inhibitor SHP099.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12524
Oncolytic activity of canine distemper virus in canine mammary tubular adenocarcinoma cells.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12466
The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxil) exerts anti-tumour effects in vitro independent of cyclooxygenase-2 expression levels.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12470
Canine intranasal tumours treated with alternating carboplatin and doxorubin in conjunction with oral piroxicam: 29 cases
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12443
A comparison of 12- and 19-week CHOP protocols using non-randomized, contemporaneous controls.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/VCO.12465
Epidemiological, pathological, and immunohistochemical aspects of 125 cases of feline lymphoma in southern brazil.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12535
Canine oral primary melanoma cells exhibit shift to mesenchymal phenotype and phagocytic behaviour.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12464
MicroRNA fingerprints in serum and whole blood of sarcoid‐affected horses as potential non‐invasive diagnostic biomarkers
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12451
Retrospective comparison of first line adjuvant anthracycline vs metronomic-based chemotherapy protocols in the treatment of stage I and II canine splenic haemangiosarcoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12548
Nectin-4 and p63 immunohistochemical expression in canine prostate tumourigenesis.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12469
Evaluation of leukocyte counts and neutrophil-to-lymphocyte ratio as predictors of local recurrence of feline injection site sarcoma after curative intent surgery.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12534
Cancer stem cell populations in lymphoma in dogs and impact of cytotoxic chemotherapy
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12447
Tumour necrosis factor-related apoptosis-inducing ligand induces apoptosis in canine hemangiosarcoma cells in vitro.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12471
Clinical outcomes, ultrastructure, and immunohistochemical features of canine high-grade olfactory neuroblastoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12512
Establishment of cell line and in vivo mouse model of canine Langerhans cell histiocytosis.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12476
Minimal residual disease in lymph nodes after achievement of complete remission predicts time to relapse in dogs with large B-cell lymphoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12453
Pilot Study to Evaluate the Efficacy of Lymphotropic Nanoparticle Enhanced MRI for Diagnosis of Metastatic Disease in Canine Head and Neck Tumors.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12527
Acute phase proteins and biomarkers of oxidative status in feline spontaneous malignant mammary tumours.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12486
Comparison of three mobilization protocols for peripheral blood stem cell apheresis with Spectra Optia continuous mononuclear cell protocol in healthy dogs
来源期刊：Veterinary and Comparative OncologyDOI：10.1111/vco.12446
Preliminary assessment of serum clusterin as a potential biomarker for canine lymphoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12550
Stereotactic radiation therapy for canine multilobular osteochondrosarcoma: Eight cases.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12481
In vitro and in vivo effects of toceranib phosphate on canine osteosarcoma cell lines and xenograft orthotopic models.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12562
Investigation of thyroid function in dogs treated with the tyrosine kinase inhibitor toceranib.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12538
Emerging Therapeutic Approaches for Canine Sarcomas: Pushing the Boundaries Beyond the Conventional.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12554
Radiotherapy isocenters verified by matching to bony landmarks of the canine and feline head differ when localized using volumetric vs planar imaging.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12522
Definitive-intent intensity-modulated radiation therapy for treatment of canine prostatic carcinoma: a multi-institutional retrospective study.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12561
Analysis of radiosensitivity of cancer stem-like cells derived from canine cancer cell lines.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12452
In-vitro study to assess the efficacy of CDK4/6 inhibitor Palbociclib (PD-0332991) for treating canine mammary tumors.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12514
Analysis of outcome in dogs that undergo secondary amputation as an end-point for managing complications related to limb salvage surgery for treatment of appendicular osteosarcoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12513
Ventral Mandibulectomy for removal of oral tumors in the dog: Surgical technique and results in 19 cases.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12472
The potential of the combined use of targeted Type I interferon pathway inhibitors and oncolytic viruses to treat sarcomas.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12547
Owner perceptions of radiotherapy treatment for veterinary patients with cancer.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12454
The controversial histologic classification of canine subcutaneous whorling tumors: the path to perivascular wall tumors.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12559
Aberrantly expressed snoRNA, snRNA, piRNA and tRFs in canine melanoma.
来源期刊：Veterinary and comparative oncologyDOI：10.1111/vco.12558
