Trends in Molecular Medicine's objective is to facilitate communication between groups of highly trained professionals with distinct backgrounds and skills, whose common goals are to understand and explain the molecular basis of disease with a view to new clinical practice. Trends in Molecular Medicine is a resource for students and professionals alike, who have information needs that transcend the traditional clinical or scientific categorisation.Trends in Molecular Medicine includes review articles on the genetic basis of disease, but 'molecular' does not only mean DNA. The diagnostic role of genetic processes is clear, but major benefits in health and disease are also provided by other molecules: enzymes, antibiotics, hormones, metals, carbohydrates, lipids, vitamins, synthetic organic and inorganic polymers. Such benefits are discussed and evaluated by Trends in Molecular Medicine. Furthermore 'Medicine' involves a vital societal element; molecular intervention raises controversial ethical, legal and financial issues. All these issues are addressed in Trends in Molecular Medicine in a style that builds on 25 years' experience of publishing the Trends Journals.
《分子医学趋势》的目标是促进具有不同背景和技能的训练有素的专业人员之间的交流，他们的共同目标是了解和解释疾病的分子基础，以期开展新的临床实践。《分子医学趋势》是为学生和专业人士提供的资源，他们的信息需求超越了传统的临床或科学分类。《分子医学趋势》包括关于疾病遗传基础的综述文章，但“分子”并不仅仅指DNA。遗传过程的诊断作用是明确的，但其他分子也为健康和疾病提供了主要益处：酶、抗生素、激素、金属、碳水化合物、脂类、维生素、合成的有机和无机聚合物。分子医学趋势讨论和评价了这些益处。此外，“医学”涉及一个重要的社会因素;分子干预引起了有争议的伦理、法律的和财政问题。所有这些问题都在《分子医学趋势》中以一种建立在25年出版《趋势》杂志经验基础上的风格得到了解决。
Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.006
Ceramides as Novel Disease Biomarkers.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.10.009
Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.002
Principles of Resistance to Targeted Cancer Therapy: Lessons from Basic and Translational Cancer Biology.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.009
RIP Kinases in Liver Cell Death, Inflammation and Cancer.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.10.007
Immunomodulatory TGF-β Signaling in Hepatocellular Carcinoma.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.06.007
Pharmacological Modulation of the STING Pathway for Cancer Immunotherapy.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.007
Mechanisms of Genomic Instability in Breast Cancer.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.04.004
Road Map for Development of Stem Cell-Based Alternative Test Methods.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.04.003
tRNA Deregulation and Its Consequences in Cancer.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.011
Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases?
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.001
DEL-1-Regulated Immune Plasticity and Inflammatory Disorders.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.010
Surviving Acute Organ Failure: Cell Polyploidization and Progenitor Proliferation.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.006
Microglia as Dynamic Cellular Mediators of Brain Function.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.08.013
Annexin-A1 - A Blessing or a Curse in Cancer?
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.004
Missing Pieces to the Endocannabinoid Puzzle.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.002
Checkpoint Inhibition and Infectious Diseases: A Good Thing?
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.08.004
Saving Problematic Mucosae: SPMs in Intestinal Mucosal Inflammation and Repair.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.004
Pharmacological Autophagy Regulators as Therapeutic Agents for Inflammatory Bowel Diseases.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.03.002
Visualizing Mitochondrial Form and Function within the Cell.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.09.009
Vitamins for the Gut Microbiome.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.005
Strengthening Causal Inference for Complex Disease Using Molecular Quantitative Trait Loci.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.10.004
Immunometabolism around the Clock.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.04.013
PTEN Mutations Trigger Resistance to Immunotherapy.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.03.003
DNA Methylation-Based Point-of-Care Cancer Detection: Challenges and Possibilities.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.014
NIK as a Druggable Mediator of Tissue Injury.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.005
Pioneer Factors and Architectural Proteins Mediating Embryonic Expression Signatures in Cancer.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.01.008
Assessing Neuroprotective Agents for Aβ-Induced Neurotoxicity.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.013
Semaphorins as Regulators of Phenotypic Plasticity and Functional Reprogramming of Cancer Cells.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.01.010
Novel Direct Conversion of Microglia to Neurons.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.005
Modifying the Organ Matrix Pre-engraftment: A New Transplant Paradigm?
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.04.002
Pluripotent Stem Cell-Based Therapeutics for Muscular Dystrophies.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.07.004
The Advent of Human Life Data Economics.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.002
Remaining Hurdles for Tissue-Engineering the Temporomandibular Joint Disc.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2018.12.007
The Role of Reactive Oxygen Species in In Vitro Cardiac Maturation.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.04.005
Self-DNA Sensing Fuels HIV-1-Associated Inflammation.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.06.004
Editing Cytoprotective Autophagy in Glioma: An Unfulfilled Potential for Therapy.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.001
Molecular Treasures of Cancer Cell Lines.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.06.002
New Insights and Perspectives in Fanconi Anemia Research.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.01.003
The Hard-To-Close Window of T-Type Calcium Channels.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.03.001
Resolving Spliceosomal Malfunctions Advances RNA-Based Therapeutics.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.009
Cheating Death: New Molecules Block BAX.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.008
Glutamine Skipping the Q into Mitochondria.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.004
Myosin II in Cancer Cells Shapes the Immune Microenvironment.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.011
Stem Cell-Derived Human Gametes: The Public Engagement Imperative.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.01.005
Hijacking of GABAA Receptors by Mutant Glycine Receptors.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.08.010
The 3D Genome: EZH2 Comes into the Fold.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.02.013
A Single Human Neuron Approach to Synapse Function.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.05.005
Boosting Antitumour Immunity through Targeted Delivery of Interferon-α.
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.09.001
Do Two Mitochondrial Wrongs Help Make Cells Right?
来源期刊：Trends in molecular medicineDOI：10.1016/j.molmed.2019.11.007
