Translational Research (formerly The Journal of Laboratory and Clinical Medicine) delivers original investigations in the broad fields of laboratory, clinical, and public health research. Published monthly since 1915, it keeps readers up-to-date on significant biomedical research from all subspecialties of medicine. Interdisciplinary and cross-disciplinary in scope, it aims to expedite the translation of scientific discovery into new or improved standards of care and promotes a wide-ranging exchange between basic, preclinical, clinical, epidemiologic, and health outcomes research. It encourages submission of studies describing preclinical research with potential for application to human disease, and studies describing research obtained from preliminary human experimentation with potential to refine the understanding of biological principles underpinning human disease. Also encouraged are studies describing public health research with potential for application to the clinic, disease prevention, or healthcare policy.
转化研究（前身为《实验室和临床医学杂志》）在实验室、临床和公共卫生研究的广泛领域提供原创性研究。自1915年以来每月出版，它使读者最新的重要生物医学研究，从所有子专业的医学。在范围上是跨学科和跨学科的，其目的是加快将科学发现转化为新的或改进的护理标准，并促进基础、临床前、临床、流行病学和健康结果研究之间的广泛交流。它鼓励提交描述临床前研究的研究，这些研究有可能应用于人类疾病，以及描述从初步人体实验中获得的研究的研究，这些研究有可能完善对人类疾病基础生物学原理的理解。还鼓励进行描述公共卫生研究的研究，这些研究有可能应用于临床、疾病预防或医疗保健政策。
Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.003
DNA methylation as a transcriptional regulator of the immune system
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.08.001
Establishment of vaginal microbiota composition in early pregnancy and its association with subsequent preterm prelabor rupture of the fetal membranes
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.005
Chronic exposure to e‐cig aerosols during early development causes vascular dysfunction and offspring growth deficits
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2019.01.001
The role of gamma delta T lymphocytes in breast cancer: a review
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.08.005
A proof‐of‐concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.11.003
Epigenetics in amyotrophic lateral sclerosis: a role for histone post‐translational modifications in neurodegenerative disease
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.002
Targeting epigenetic mechanisms in diabetic wound healing
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.001
Circulating miR‐143‐3p inhibition protects against insulin resistance in Metabolic Syndrome via targeting of the insulin‐like growth factor 2 receptor
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.09.006
The connection of circadian rhythm to inflammatory bowel disease
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.001
Enhancing responsiveness of pancreatic cancer cells to gemcitabine treatment under hypoxia by heme oxygenase‐1 inhibition
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.008
Proteasome biology and therapeutics in cardiac diseases
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.09.003
A long‐term treatment with taurine prevents cardiac dysfunction in mdx mice
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.09.004
T helper 2 differentiation is necessary for development of lymphedema
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.003
Small molecule inhibition of dipeptidyl peptidase‐4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.006
Alcohol dependence treating agent, acamprosate, prevents traumatic brain injury‐induced neuron death through vesicular zinc depletion
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2019.01.002
A review on the interactions between the tumor microenvironment and androgen receptor signaling in prostate cancer
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.11.004
Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.002
Macrophage depletion by clodronate attenuates bone morphogenetic protein‐7 induced M2 macrophage differentiation and improved systolic blood velocity in atherosclerosis
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.07.006
ALDH1‐positive intratumoral stromal cells indicate differentiated epithelial‐like phenotype and good prognosis in prostate cancer
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.08.007
Systematic review and meta-analysis of experimental studies evaluating the organ protective effects of histone deacetylase inhibitors
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.11.002
Molecular discoveries and treatment strategies by direct reprogramming in cardiac regeneration
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.07.012
Changes in CDKN2A/2B expression associate with T‐cell phenotype modulation in atherosclerosis and type 2 diabetes mellitus
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.08.003
SMAD7 is a novel independent predictor of survival in patients with cutaneous melanoma
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.09.002
Tetraspanin CD151 impairs heterodimerization of ErbB2/ErbB3 in breast cancer cells
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.007
BM‐MSCs‐derived ECM modifies multiple myeloma phenotype and drug response in a source‐dependent manner
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2019.01.003
Increased circulating levels of Epidermal Growth Factor‐like Domain 7 in pregnant women affected by preeclampsia
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.004
Müller cells in pathological retinal angiogenesis
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.12.006
Dysfunctional high density lipoprotein failed to rescue the function of oxidized low density lipoprotein‐treated endothelial progenitor cells: a novel index for the prediction of HDL functionality
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.09.005
Glycomics in rare diseases: from diagnosis tomechanism
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.005
Toward genome editing in X-linked RP—development of a mouse model with specific treatment relevant features
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.08.006
A small molecule Hedgehog agonist HhAg1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.10.004
Triple‐tyrosine kinase inhibition attenuates pulmonary arterial hypertension and neointimal formation
来源期刊：Translational ResearchDOI：10.1016/j.trsl.2018.07.010
