Translational Oncology publishes the results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients. Translational Oncology will publish laboratory studies of novel therapeutic interventions as well as clinical trials which evaluate new treatment paradigms for cancer. Peer reviewed manuscript types include Original Reports, Reviews and Editorials.
转化肿瘤学发表了新的研究结果，这些研究将实验室和临床环境联系起来，包括风险评估、细胞和分子表征、预防、检测、诊断和治疗人类癌症，总体目标是改善肿瘤患者的临床护理。转化肿瘤学将发表新的治疗干预的实验室研究以及评估癌症新治疗模式的临床试验。同行评审的稿件类型包括原始报告、评审和社论。
A Phase Ib Study of Pembrolizumab as Second-Line Therapy for Chinese Patients With Advanced or Metastatic Melanoma (KEYNOTE-151)☆☆☆☆☆☆
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.02.007
The Role of TGF-β and Its Receptors in Gastrointestinal Cancers
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.11.010
Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.014
Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and Reduces Prohibitin Protein in Glioblastoma Multiforme Cells12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.12.004
RRx-001 Acts as a Dual Small Molecule Checkpoint Inhibitor by Downregulating CD47 on Cancer Cells and SIRP-α on Monocytes/Macrophages
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.12.001
Advances in Molecular Mechanisms and Treatment of Radiation-Induced Pulmonary Fibrosis
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.09.009
Cancer Immunotherapies and Humanized Mouse Drug Testing Platforms1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.020
Attenuation of CD47-SIRPα Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.007
High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.010
High Glucose Promotes Human Glioblastoma Cell Growth by Increasing the Expression and Function of Chemoattractant and Growth Factor Receptors1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.016
Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.014
HPV and Oropharyngeal Cancer in the Eighth Edition of the TNM Classification: Pitfalls in Practice
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.05.009
Multi-Spectral Fluorescence Imaging of Colon Dysplasia InVivo Using a Multi-Spectral Endoscopy System1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.006
STAT-3 RNAscope Determination in Human Diffuse Large B-Cell Lymphoma1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.12.008
Novel Synergistic Combination of Mitotic Arrest and Promotion of Apoptosis for Treatment of Pancreatic Adenocarcinoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.01.009
Metformin Treatment for Diabetes Mellitus Correlates with Progression and Survival in Colorectal Carcinoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.10.011
An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.02.012
Circulating miRNA Profiling of Women at High Risk for Ovarian Cancer
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.01.006
Knockdown of Lumican Inhibits Proliferation and Migration of Bladder Cancer
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.05.014
Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.11.002
Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.09.004
Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.09.013
Lysosome Inhibition by Mefloquine Preferentially Enhances the Cytotoxic Effects of Tyrosine Kinase Inhibitors in Blast Phase Chronic Myeloid Leukemia1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.06.001
Isolated 5′ Signals Are an Atypical Pattern To Be Considered as Positive for ALK Rearrangement: A Brief Report of Three Cases and Review of the Literature1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.02.015
Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.08.006
UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.003
A Pilot Prospective Study of Refractory Solid Tumor Patients for NGS-Based Targeted Anticancer Therapy12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.011
Monitoring Progression of Ductal Carcinoma In Situ Using Photoacoustics and Contrast-Enhanced Ultrasound
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.018
Towards the Optical Detection of Field Cancerization in the Buccal Mucosa of Patients with Lung Cancer12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.018
Preclinical Pharmacokinetic and Safety Studies of Copper-Diacetyl-Bis(N4-Methylthiosemicarbazone) (Cu-ATSM): Translational Studies for Internal Radiotherapy
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.05.017
Antioxidation and Antiapoptosis Characteristics of Heme Oxygenase-1 Enhance Tumorigenesis of Human Prostate Carcinoma Cells
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.10.008
DIVERSet JAG Compounds Inhibit Topoisomerase II and Are Effective Against Adult and Pediatric High-Grade Gliomas
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.007
Arterial Spin Labeling for Glioma Grade Discrimination: Correlations with IDH1 Genotype and 1p/19q Status
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.02.013
Metadherin Is a Prognostic Apoptosis Modulator in Mesothelioma Induced via NF-κB-Mediated Signaling1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.03.005
Predicting Therapeutic Efficacy of Vascular Disrupting Agent CA4P in Rats with Liver Tumors by Hepatobiliary Contrast Agent Mn-DPDP-Enhanced MRI
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.09.010
PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.09.011
Phenotype of vigilin expressing breast cancer cells binding to the 69 nt 3′UTR element in CSF-1R mRNA
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.09.012
Functional and Phenotypic Characterization of Tumor-Infiltrating Leukocyte Subsets and Their Contribution to the Pathogenesis of Hepatocellular Carcinoma and Cholangiocarcinoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.019
Inactivation of SAG or ROC1 E3 Ligase Inhibits Growth and Survival of Renal Cell Carcinoma Cells: Effect of BIM1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.03.002
Cancer Panel Assay for Precision Oncology Clinic: Results from a 1-Year Study
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.017
Primary Central Nervous System Lymphoma: Molecular Pathogenesis and Advances in Treatment1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.11.011
Expression of Alpha-type Platelet-derived Growth Factor Receptor–influenced Genes Predicts Clinical Outcome in Glioma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.10.002
Intermittent Versus Continuous Dosing of MAPK Inhibitors in the Treatment of BRAF-Mutated Melanoma
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.10.003
Smoking-Induced SLPI Expression Hinders HPV Infections Also in Squamous Cell Carcinomas of the Vulva
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.09.004
Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential12
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.006
Phosphoproteome Profiling Reveals Multifunctional Protein NPM1 as part of the Irradiation Response of Tumor Cells
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2018.10.015
Cytological Immunostaining of HMGA2, LRP1B, and TP63 as Potential Biomarkers for Triaging Human Papillomavirus-Positive Women1
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.04.012
DZIP1 Promotes Proliferation, Migration, and Invasion of Oral Squamous Carcinoma Through the GLI1/3 Pathway
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.07.005
Genetic Profiling of Breast Cancer with and Without Preexisting Metabolic Disease
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.09.008
Does Bone-targeted Therapy Benefit Patients with Metastatic Renal Cell Carcinoma?
来源期刊：Translational OncologyDOI：10.1016/j.tranon.2019.10.009
