Retrovirology is an open access, online journal that publishes stringently peer-reviewed, high-impact articles on host-pathogen interactions, fundamental mechanisms of replication, immune defenses, animal models, and clinical science relating to retroviruses. Retroviruses are pleiotropically found in animals. Well-described examples include avian, murine and primate retroviruses. Two human retroviruses are especially important pathogens. These are the human immunodeficiency virus, HIV, and the human T-cell leukemia virus, HTLV. HIV causes AIDS while HTLV-1 is the etiological agent for adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. Retrovirology aims to cover comprehensively all aspects of human and animal retrovirus research.
《逆转录病毒学》是一本开放获取的在线杂志,发表关于宿主-病原体相互作用、复制的基本机制、免疫防御、动物模型和逆转录病毒相关临床科学的严格同行评审的高影响力文章。逆转录病毒在动物中具有多效性。详细描述的实例包括禽、鼠和灵长类逆转录病毒。两种人类逆转录病毒是特别重要的病原体。这些病毒是人类免疫缺陷病毒(HIV)和人类T细胞白血病病毒(HTLV)。HIV导致AIDS,而HTLV-1是成人T细胞白血病和HTLV-1相关脊髓病/热带痉挛性下肢轻瘫的病原体。逆转录病毒学旨在全面涵盖人类和动物逆转录病毒研究的所有方面。
Host mRNA decay proteins influence HIV-1 replication and viral gene expression in primary monocyte-derived macrophages
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0465-2
Hypericin-photodynamic therapy inhibits the growth of adult T-cell leukemia cells through induction of apoptosis and suppression of viral transcription
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0467-0
Comparative virology of HTLV-1 and HTLV-2
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0483-0
Bovine leukemia virus proviral load is more strongly associated with bovine major histocompatibility complex class II DRB3 polymorphism than with DQA1 polymorphism in Holstein cow in Japan
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0476-z
Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0494-x
Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0464-3
CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0477-y
Molecular epidemiology, genetic variability and evolution of HTLV-1 with special emphasis on African genotypes
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0504-z
Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0478-x
NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0492-z
HTLV-1 infection of myeloid cells: from transmission to immune alterations
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0506-x
Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0487-9
Restriction factors in human retrovirus infections and the unprecedented case of CIITA as link of intrinsic and adaptive immunity against HTLV-1
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0498-6
Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0484-z
p30 protein: a critical regulator of HTLV-1 viral latency and host immunity
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0501-2
Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0472-3
Functional analysis of the secondary HIV-1 capsid binding site in the host protein cyclophilin A
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0471-4
The autophagy protein ATG9A promotes HIV-1 infectivity
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0480-3
Effect of transcription inhibition and generation of suppressive viral non-coding RNAs
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0475-0
HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0500-3
Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0466-1
STLV-1 as a model for studying HTLV-1 infection
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0503-0
Immunovirological markers in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0499-5
BLV: lessons on vaccine development
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0488-8
NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0479-9
Cardiovascular disease risk in an urban African population: a cross-sectional analysis on the role of HIV and antiretroviral treatment
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0497-7
Deltaretroviruses have circulated since at least the Paleogene and infected a broad range of mammalian species
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0495-9
Isolation of the Arawete and Asurini Indians keeps the tribes free from HTLV infection during 36 years of follow-up
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0490-1
Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0502-1
HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0505-y
Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0473-2
HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0507-9
Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0468-z
On the generation of the MSD-Ѱ class of defective HIV proviruses
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0481-2
Effect of induced dNTP pool imbalance on HIV-1 reverse transcription in macrophages
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0491-0
Interaction of HIV-1 integrase with polypyrimidine tract binding protein and associated splicing factor (PSF) and its impact on HIV-1 replication
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0474-1
Analysis of herpes simplex type 1 gB, gD, and gH/gL on production of infectious HIV-1: HSV-1 gD restricts HIV-1 by exclusion of HIV-1 Env from maturing viral particles
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0470-5
An insight to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis; evidence from high-throughput data integration and meta-analysis
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0508-8
The KT Jeang Prize 2019: Reuben S. Harris
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0486-x
A trip down memory lane with Retrovirology
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0485-y
Engineering and characterising a novel, highly potent bispecific antibody iMab-CAP256 that targets HIV-1
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0493-y
Obituary: Jonas Blomberg (1944–2019)
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0469-y
Mutations of Glu560 within HIV-1 Envelope Glycoprotein N-terminal heptad repeat region contribute to resistance to peptide inhibitors of virus entry
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0496-8
Correction to: CCR5 editing by Staphylococcus aureus Cas9 in human primary CD4+ T cells and hematopoietic stem/progenitor cells promotes HIV-1 resistance and CD4+ T cell enrichment in humanized mice
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0482-1
Characterization of resistance to a potent d-peptide HIV entry inhibitor
来源期刊:RetrovirologyDOI:10.1186/s12977-019-0489-7