Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.
The Microbiology of Bloodstream Infection: 20-Year Trends from the SENTRY Antimicrobial Surveillance Program
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00355-19
Novel Plasmid-Mediated tet(X5) Gene Conferring Resistance to Tigecycline, Eravacycline, and Omadacycline in a Clinical Acinetobacter baumannii Isolate
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01326-19
Low Level of Antifungal Resistance in Iranian Isolates of Candida glabrata Recovered from Blood Samples in a Multicenter Study from 2015 to 2018 and Potential Prognostic Values of Genotyping and Sequencing of PDR1
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02503-18
Klebsiella quasipneumoniae Provides a Window into Carbapenemase Gene Transfer, Plasmid Rearrangements, and Patient Interactions with the Hospital Environment
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02513-18
PD-1 Blockade and TLR7 Activation Lack Therapeutic Benefit in Chronic Simian Immunodeficiency Virus-Infected Macaques on Antiretroviral Therapy
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01163-19
Characterization of mcr-5-Harboring Salmonella enterica subsp. enterica Serovar Typhimurium Isolates from Animal and Food Origin in Germany
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00063-19
EUCAST Susceptibility Testing of Isavuconazole: MIC Data for Contemporary Clinical Mold and Yeast Isolates
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00073-19
Rifabutin Is Active against Mycobacterium abscessus in Mice
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01943-19
Next-Generation-Sequencing-Based Hospital Outbreak Investigation Yields Insight into Klebsiella aerogenes Population Structure and Determinants of Carbapenem Resistance and Pathogenicity
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02577-18
Synthesis and Leishmanicidal Activity of Novel Urea, Thiourea, and Selenourea Derivatives of Diselenides
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02200-18
Impact of an Antimicrobial Stewardship Intervention on Within- and Between-Patient Daptomycin Resistance Evolution in Vancomycin-Resistant Enterococcus faecium
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01800-18
In Vivo Pharmacodynamic Profile of Ceftibuten-Clavulanate Combination against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in the Murine Thigh Infection Model
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00145-19
Evaluation of the Activity of a Combination of Three Bacteriophages Alone or in Association with Antibiotics on Staphylococcus aureus Embedded in Biofilm or Internalized in Osteoblasts
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02231-19
In Vitro Activity of Levonadifloxacin (WCK 771) against Chlamydia pneumoniae
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01048-19
Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00547-19
TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug’s Uncoupler Activity
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01540-19
Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02410-18
Iron Chelator Deferasirox Reduces Candida albicans Invasion of Oral Epithelial Cells and Infection Levels in Murine Oropharyngeal Candidiasis
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02152-18
Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02338-18
Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00710-19
Challenging antimicrobial susceptibility and evolution of resistance (OXA-681) during treatment of a Pseudomonas aeruginosa ST175 clone long-term nosocomial infection.
来源期刊：Antimicrobial agents and chemotherapyDOI：10.1128/AAC.01110-19
Acquisition of Cross-Resistance to Bedaquiline and Clofazimine following Treatment for Tuberculosis in Pakistan
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00915-19
Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02266-18
Molecular Testing of Serial Blood Specimens from Patients with Early Lyme Disease during Treatment Reveals Changing Coinfection with Mixtures of Borrelia burgdorferi Genotypes
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00237-19
Evolution of Carbapenem-Resistant Serotype K1 Hypervirulent Klebsiella pneumoniae by Acquisition of blaVIM-1-Bearing Plasmid
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01056-19
Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00397-19
Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01772-19
Detection of Candida auris Antifungal Drug Resistance Markers Directly from Clinical Skin Swabs
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01754-19
Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00199-19
Early Dissemination of qnrE1 in Salmonella enterica Serovar Typhimurium from Livestock in South America
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00571-19
Carbapenem-Susceptible OXA-23-Producing Proteus mirabilis in the French Community
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00191-19
Repurposing of Ribavirin as an Adjunct Therapy against Invasive Candida Strains in an In Vitro Study
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00263-19
Cefoperazone/Sulbactam versus Cefepime in the Treatment of Hospital-Acquired Pneumonia/Healthcare-Associated Pneumonia: A Randomized Non-inferiority Trial.
来源期刊：Antimicrobial agents and chemotherapyDOI：10.1128/AAC.00023-19
Emergence of an NDM-5-Producing Hypervirulent Klebsiella pneumoniae Sequence Type 35 Strain with Chromosomal Integration of an Integrative and Conjugative Element, ICEKp1
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01675-19
Population Pharmacokinetic Study of Prophylactic Fluconazole in Preterm Infants for Prevention of Invasive Candidiasis
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01960-18
A Randomized Open-Label Evaluation of the Antimalarial Prophylactic Efficacy of Azithromycin-Piperaquine versus Sulfadoxine-Pyrimethamine in Pregnant Papua New Guinean Women
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00302-19
Lethal Mutagenesis of Rift Valley Fever Virus Induced by Favipiravir
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00669-19
Renal Glycosuria as a Novel Early Sign of Colistin-Induced Kidney Damage in Mice
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01650-19
Ceftolozane-Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains with Genetically Defined Mechanisms of Resistance
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00344-19
Aspergillus fumigatus Clinical Isolates Carrying CYP51A with TR34/L98H/S297T/F495I Substitutions Detected after Four-Year Retrospective Azole Resistance Screening in Brazil
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02059-19
Epidemiological Trends of Fungemia in Greece with a Focus on Candidemia during the Recent Financial Crisis: a 10-Year Survey in a Tertiary Care Academic Hospital and Review of Literature
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01516-19
Comparing Antimicrobial Susceptibilities among Mycoplasma pneumoniae Isolates from Pediatric Patients in Japan between Two Recent Epidemic Periods
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02517-18
Conjugal Transfer, Whole-Genome Sequencing, and Plasmid Analysis of Four mcr-1-Bearing Isolates from U.S. Patients
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02417-18
Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01082-19
Erratum for Li et al., “Antibacterial Properties of Magnesium In Vitro and in an In Vivo Model of Implant-Associated Methicillin-Resistant Staphylococcus aureus Infection”
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.00313-19
Patient-Derived Cytomegaloviruses with Different Ganciclovir Sensitivities from UL97 Mutation Retain Their Replication Efficiency and Some Kinase Activity In Vitro
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02425-18
Inhibition Activity of Avibactam against Nocardia farcinica β-Lactamase FARIFM10152
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01551-19
NNRTI Hyper-Susceptibility and Resistance: Mutational Analysis of Residue 181 in HIV-1 Reverse Transcriptase.
来源期刊：Antimicrobial agents and chemotherapyDOI：10.1128/AAC.00676-19
Barrier to Resistance of Dolutegravir in Two-Drug Combinations
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.02104-18
Reply to Nevez and Le Gal, “Caspofungin and Pneumocystis Pneumonia: It Is Time To Go Ahead”
来源期刊：Antimicrobial Agents and ChemotherapyDOI：10.1128/AAC.01320-19
