Bacteria, fungi, parasites, prions and viruses cause a plethora of diseases that have important medical, agricultural, and economic consequences. Moreover, the study of microbes continues to provide novel insights into such fundamental processes as the molecular basis of cellular and organismal function.
细菌、真菌、寄生虫、朊病毒和病毒引起大量疾病，这些疾病具有重要的医学、农业和经济后果。此外，对微生物的研究继续为诸如细胞和生物体功能的分子基础等基本过程提供新的见解。
The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007756
Microbiota-mediated disease resistance in plants
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007740
On the evolutionary ecology of multidrug resistance in bacteria
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007763
The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007934
Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007817
Human polyomavirus BKV infection of endothelial cells results in interferon pathway induction and persistence
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007505
Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007535
DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007742
CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007748
The Human Cytomegalovirus UL38 protein drives mTOR-independent metabolic flux reprogramming by inhibiting TSC2
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007569
Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007644
Immune-inducible non-coding RNA molecule lincRNA-IBIN connects immunity and metabolism in Drosophila melanogaster
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007504
Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007816
Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008041
Candida albicans triggers NADPH oxidase-independent neutrophil extracellular traps through dectin-2
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008096
Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008087
Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007265
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008074
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008062
Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008072
An ortholog of Plasmodium falciparum chloroquine resistance transporter (PfCRT) plays a key role in maintaining the integrity of the endolysosomal system in Toxoplasma gondii to facilitate host invasion
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007775
Roles, function and relevance of LAG3 in HIV infection
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007429
CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008122
EhP3, a homolog of 14-3-3 family of protein participates in actin reorganization and phagocytosis in Entamoeba histolytica
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007789
Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007925
Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008077
The alternative cap-binding complex is required for antiviral defense in vivo
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008155
Vaccinia viral A26 protein is a fusion suppressor of mature virus and triggers membrane fusion through conformational change at low pH
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007826
SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007710
The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007877
Human apolipoprotein E promotes hepatitis B virus infection and production
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007874
NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007992
Chromatin dynamics and the transcriptional competence of HSV-1 genomes during lytic infections
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008076
Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008061
Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007940
A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008192
Dengue virus reduces AGPAT1 expression to alter phospholipids and enhance infection in Aedes aegypti
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008199
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008194
Trypanosoma brucei infection protects mice against malaria
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008145
The HPV-18 E7 CKII phospho acceptor site is required for maintaining the transformed phenotype of cervical tumour-derived cells
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007769
HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007922
Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007918
Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008177
The ABCs of wheeze: Asthma and bacterial communities
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007645
Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007758
Novel replisome-associated proteins at cellular replication forks in EBV-transformed B lymphocytes
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008228
EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007898
Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008006
Correction: The bZIP Transcription Factor MoAP1 Mediates the Oxidative Stress Response and is Critical for Pathogenicity of the Rice Blast Fungus Magnaporthe oryzae
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1008196
Correction: Small-Molecule Inhibitors of Dengue-Virus Entry
来源期刊：PLoS PathogensDOI：10.1371/journal.ppat.1007553
