PLOS Neglected Tropical Diseases publishes research devoted to the pathology, epidemiology, prevention, treatment and control of the neglected tropical diseases (NTDs), as well as relevant public policy.The NTDs are defined as a group of poverty-promoting chronic infectious diseases, which primarily occur in rural areas and poor urban areas of low-income and middle-income countries. Their impact on child health and development, pregnancy, and worker productivity, as well as their stigmatizing features limit economic stability.All aspects of these diseases are considered, including:PathogenesisClinical featuresPharmacology and treatmentDiagnosisEpidemiologyVector biologyVaccinology and preventionDemographic, ecological and social determinantsPublic health and policy aspects (including cost-effectiveness analyses).
PLOS《被忽视的热带病》发表了关于被忽视的热带病的病理学、流行病学、预防、治疗和控制以及相关公共政策的研究。被忽视的热带病被定义为一组导致贫困的慢性传染病，主要发生在中低收入国家的农村地区和贫困城市地区。这些疾病对儿童健康和发育、怀孕和工人生产力的影响，以及它们的污名化特征限制了经济稳定。这些疾病的所有方面都被考虑在内，包括：病因学临床特征药理学和治疗诊断流行病学载体生物学疫苗学和预防人口统计学、生态学和社会决定因素公共卫生和政策方面（包括成本效益分析）。
High-accuracy detection of malaria vector larval habitats using drone-based multispectral imagery
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007105
Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007152
Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort study
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007216
Does prior dengue virus exposure worsen clinical outcomes of Zika virus infection? A systematic review, pooled analysis and lessons learned
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007060
A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007112
Imported strongyloidiasis: Data from 1245 cases registered in the +REDIVI Spanish Collaborative Network (2009-2017)
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007399
Update on the geographical distribution and prevalence of Aedes aegypti and Aedes albopictus (Diptera: Culicidae), two major arbovirus vectors in Cameroon
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007137
Expression of Bacillus thuringiensis toxin Cyt2Ba in the entomopathogenic fungus Beauveria bassiana increases its virulence towards Aedes mosquitoes
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007590
Incidence dynamics and investigation of key interventions in a dengue outbreak in Ningbo City, China
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007659
The landscape of enteric pathogen exposure of young children in public domains of low-income, urban Kenya: The influence of exposure pathway and spatial range of play on multi-pathogen exposure risks
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007292
Intestinal parasitic infection alters bone marrow derived dendritic cell inflammatory cytokine production in response to bacterial endotoxin in a diet-dependent manner
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007515
Supporting evidence for a human reservoir of invasive non-Typhoidal Salmonella from household samples in Burkina Faso
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007782
A systems biology approach for studying Wolbachia metabolism reveals points of interaction with its host in the context of arboviral infection
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007678
Proposed multidimensional framework for understanding Chagas disease healthcare barriers in the United States
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007447
Clinical and epidemiologic characteristics associated with dengue during and outside the 2016 outbreak identified in health facility-based surveillance in Ouagadougou, Burkina Faso
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007882
China’s shifting neglected parasitic infections in an era of economic reform, urbanization, disease control, and the Belt and Road Initiative
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0006946
Genetic characteristics of pathogenic Leptospira in wild small animals and livestock in Jiangxi Province, China, 2002–2015
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007513
The prevalence of schistosomiasis in Uganda: A nationally representative population estimate to inform control programs and water and sanitation interventions
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007617
Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007894
Anti-leishmanial activity of Brevinin 2R and its Lauric acid conjugate type against L. major: In vitro mechanism of actions and in vivo treatment potentials
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007217
A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007345
Loop-mediated Isothermal Amplification and nested PCR of the Internal Transcribed Spacer (ITS) for Histoplasma capsulatum detection
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007692
High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007747
Application of a targeted-enrichment methodology for full-genome sequencing of Dengue 1-4, Chikungunya and Zika viruses directly from patient samples
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007184
Leptospirosis as a risk factor for chronic kidney disease: A systematic review of observational studies
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007458
Regulatory T cells and IgE expression in duodenal mucosa of Strongyloides stercoralis and human T lymphotropic virus type 1 co-infected patients
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007415
Implementation of guppy fish (Poecilia reticulata), and a novel larvicide (Pyriproxyfen) product (Sumilarv 2MR) for dengue control in Cambodia: A qualitative study of acceptability, sustainability and community engagement
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007907
Cinnamomum cassia exhibits antileishmanial activity against Leishmania donovani infection in vitro and in vivo
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007227
Hydroclimatic drivers of highly seasonal leptospirosis incidence suggest prominent soil reservoir of pathogenic Leptospira spp. in rural western China
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007968
Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007436
Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007245
Negligible exposure to nifurtimox through breast milk during maternal treatment for Chagas Disease
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007647
Genotype diversity and distribution of Mycobacterium bovis from livestock in a small, high-risk area in northeastern Sicily, Italy
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007546
Unveil the transcriptional landscape at the Cryptococcus-host axis in mice and nonhuman primates
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007566
The cost-effectiveness of the use of selective media for the diagnosis of melioidosis in different settings
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007598
Aurora kinase protein family in Trypanosoma cruzi: Novel role of an AUK-B homologue in kinetoplast replication
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007256
Engineered action at a distance: Blood-meal-inducible paralysis in Aedes aegypti
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007579
High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007818
Refinement strategy for antivenom preparation of high yield and quality
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007431
Immune responses to O-specific polysaccharide (OSP) in North American adults infected with Vibrio cholerae O1 Inaba
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007874
The spatial epidemiology of leprosy in Kenya: A retrospective study
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007329
Serological proteomic screening and evaluation of a recombinant egg antigen for the diagnosis of low-intensity Schistosoma mansoni infections in endemic area in Brazil
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0006974
Epidemiology, ecology and human perceptions of snakebites in a savanna community of northern Ghana
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007221
Evaluation of the geographical utility of Eastern Russell’s viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007338
Estimating the impact of city-wide Aedes aegypti population control: An observational study in Iquitos, Peru
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007255
Molluscicidal activity and physiological toxicity of quaternary benzo[c]phenanthridine alkaloids (QBAs) from Macleaya cordata fruits on Oncomelania hupensis
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007740
Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007634
Outcomes of Third-Generation Cephalosporin Plus Ciprofloxacin or Doxycycline Therapy in Patients with Vibrio vulnificus Septicemia: A Propensity Score-Matched Analysis
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007478
Coverage assessment survey following trachoma mass drug administration (MDA) in six districts of Oromia, Western Ethiopia, 2017
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007924
Functional illiteracy burden in soil-transmitted helminth (STH) endemic regions of the Philippines: An ecological study and geographical prediction for 2017
来源期刊：PLoS Neglected Tropical DiseasesDOI：10.1371/journal.pntd.0007494
