An influential venue for research and commentary on the major challenges to human health worldwide, PLOS Medicine publishes articles of general interest on biomedical, environmental, social and political determinants of health. The journal emphasizes work that advances clinical practice, health policy or pathophysiological understanding to benefit health in a variety of settings.
PLOS Medicine是一个有影响力的研究和评论全球人类健康面临的主要挑战的场所,发表关于健康的生物医学、环境、社会和政治决定因素的普遍感兴趣的文章。该杂志强调的工作,推进临床实践,卫生政策或病理生理学的理解,以造福健康的各种设置。
Women’s and girls’ experiences of menstruation in low- and middle-income countries: A systematic review and qualitative metasynthesis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002803
The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002755
Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002903
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002781
Risks of stillbirth and neonatal death with advancing gestation at term: A systematic review and meta-analysis of cohort studies of 15 million pregnancies
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002838
Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002840
Redesigning care for older people to preserve physical and mental capacity: WHO guidelines on community-level interventions in integrated care
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002948
Progress in the HIV epidemic: Identifying goals and measuring success
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002729
Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002893
Integrating preexposure prophylaxis delivery in routine family planning clinics: A feasibility programmatic evaluation in Kenya
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002885
Long-term outcomes of an educational intervention to reduce antibiotic prescribing for childhood upper respiratory tract infections in rural China: Follow-up of a cluster-randomised controlled trial
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002733
Mediterranean-style diet in pregnant women with metabolic risk factors (ESTEEM): A pragmatic multicentre randomised trial
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002857
Independent and combined effects of improved water, sanitation, and hygiene (WASH) and improved complementary feeding on early neurodevelopment among children born to HIV-negative mothers in rural Zimbabwe: Substudy of a cluster-randomized trial
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002766
A simple real-time model for predicting acute kidney injury in hospitalized patients in the US: A descriptive modeling study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002861
Lay health supporters aided by mobile text messaging to improve adherence, symptoms, and functioning among people with schizophrenia in a resource-poor community in rural China (LEAN): A randomized controlled trial
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002785
Impact of reduced dose of ready-to-use therapeutic foods in children with uncomplicated severe acute malnutrition: A randomised non-inferiority trial in Burkina Faso
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002887
The association between heatwaves and risk of hospitalization in Brazil: A nationwide time series study between 2000 and 2015
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002753
Frequency of cannabis and illicit opioid use among people who use drugs and report chronic pain: A longitudinal analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002967
Rapid antiretroviral therapy initiation in low- and middle-income countries: A resource-based approach
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002723
Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002789
Cardiometabolic disease costs associated with suboptimal diet in the United States: A cost analysis based on a microsimulation model
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002981
Gender differences in grant and personnel award funding rates at the Canadian Institutes of Health Research based on research content area: A retrospective analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002935
Estimating age-stratified influenza-associated invasive pneumococcal disease in England: A time-series model based on population surveillance data
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002829
Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP)
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002883
Longitudinal engagement trajectories and risk of death among new ART starters in Zambia: A group-based multi-trajectory analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002959
Social determinants of health in relation to firearm-related homicides in the United States: A nationwide multilevel cross-sectional study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002978
Comparisons of exacerbations and mortality among regular inhaled therapies for patients with stable chronic obstructive pulmonary disease: Systematic review and Bayesian network meta-analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002958
Contact tracing versus facility-based screening for active TB case finding in rural South Africa: A pragmatic cluster-randomized trial (Kharitode TB)
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002796
Operative versus non-operative treatment for 2-part proximal humerus fracture: A multicenter randomized controlled trial
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002855
Elective and nonelective cesarean section and obesity among young adult male offspring: A Swedish population–based cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002996
Antenatal magnesium sulphate and adverse neonatal outcomes: A systematic review and meta-analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002988
Impact on child acute malnutrition of integrating a preventive nutrition package into facility-based screening for acute malnutrition during well-baby consultation: A cluster-randomized controlled trial in Burkina Faso
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002877
The gender-based violence and recovery centre at Coast Provincial General Hospital, Mombasa, Kenya: An integrated care model for survivors of sexual violence
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002886
Long-term mortality in mothers of infants with neonatal abstinence syndrome: A population-based parallel-cohort study in England and Ontario, Canada
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002974
Health checks and cardiovascular risk factor values over six years’ follow-up: Matched cohort study using electronic health records in England
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002863
Association of preterm birth with lipid disorders in early adulthood: A Swedish cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002947
Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002858
Associations of fat mass and fat-free mass accretion in infancy with body composition and cardiometabolic risk markers at 5 years: The Ethiopian iABC birth cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002888
Research to improve differentiated HIV service delivery interventions: Learning to learn as we do
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002809
Validation of the prognostic value of NF-κB p65 in prostate cancer: A retrospective study using a large multi-institutional cohort of the Canadian Prostate Cancer Biomarker Network
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002847
Mortality and recovery following moderate and severe acute malnutrition in children aged 6–18 months in rural Jharkhand and Odisha, eastern India: A cohort study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002934
Characterization of Parkinson’s disease using blood-based biomarkers: A multicohort proteomic analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002931
Designing noninferiority tuberculosis treatment trials: Identifying practical advantages for drug regimens with acceptable effectiveness
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002850
Advances in clinical trial design for development of new TB treatments—Translating international tuberculosis treatment guidelines into national strategic plans: Experiences from Belarus, South Africa, and Vietnam
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002896
Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and meta-analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002952
Addressing critical needs in the fight to end tuberculosis with innovative tools and strategies
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002795
Care practices and neonatal survival in 52 neonatal intensive care units in Telangana and Andhra Pradesh, India: A cross-sectional study
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002860
Correction: Socioeconomic position and use of healthcare in the last year of life: A systematic review and meta-analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002878
Variation of all-cause and cause-specific mortality with body mass index in one million Swedish parent-son pairs: An instrumental variable analysis
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002868
Health and medical research for all: The challenge remains open
来源期刊:PLoS MedicineDOI:10.1371/journal.pmed.1002970