PLOS Biology (eISSN-1545-7885; ISSN-1544-9173) is an open-access, peer-reviewed general biology journal published by PLOS, a nonprofit organization of scientists and physicians committed to making the world's scientific and medical literature a public resource. New articles are published online weekly; issues are published monthly.
PLOS生物学（eISSN-1545-7885; ISSN-1544-9173）是由PLOS出版的开放存取、同行评审的普通生物学期刊，PLOS是一个致力于使世界科学和医学文献成为公共资源的科学家和医生的非盈利组织。每周在线发布新文章;每月出版一期。
Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000152
DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000324
A polyploid admixed origin of beer yeasts derived from European and Asian wine populations
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000147
Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000381
Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000398
High-order interactions distort the functional landscape of microbial consortia
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000550
Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000515
Human motor cortical beta bursts relate to movement planning and response errors
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000479
A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000057
Intervention against hypertension in the next generation programmed by developmental hypoxia
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.2006552
Lateral hypothalamic neurotensin neurons promote arousal and hyperthermia
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000172
The Tara Pacific expedition—A pan-ecosystemic approach of the “-omics” complexity of coral reef holobionts across the Pacific Ocean
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000483
Systematically improved in vitro culture conditions reveal new insights into the reproductive biology of the human parasite Schistosoma mansoni
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000254
Predicting translational progress in biomedical research
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000416
Cell confinement reveals a branched-actin independent circuit for neutrophil polarity
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000457
Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000306
Evidence that nonsignificant results are sometimes preferred: Reverse P-hacking or selective reporting?
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000127
Phosphodiesterase beta is the master regulator of cAMP signalling during malaria parasite invasion
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000154
Drosophila melanogaster cloak their eggs with pheromones, which prevents cannibalism
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.2006012
Parental breeding age effects on descendants’ longevity interact over 2 generations in matrilines and patrilines
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000556
Song playbacks demonstrate slower evolution of song discrimination in birds from Amazonia than from temperate North America
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000478
Fast calcium transients in dendritic spines driven by extreme statistics
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.2006202
Cilia-based peptidergic signaling
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000566
Transmissible cancer and the evolution of sex
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000275
A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000100
Dhh1 promotes autophagy-related protein translation during nitrogen starvation
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000219
Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000311
Simu-dependent clearance of dying cells regulates macrophage function and inflammation resolution
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.2006741
Representation of abstract semantic knowledge in populations of human single neurons in the medial temporal lobe
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000290
CRL4Mahj E3 ubiquitin ligase promotes neural stem cell reactivation
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000276
The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000525
Universal antibiotic tolerance arising from antibiotic-triggered accumulation of pyocyanin in Pseudomonas aeruginosa
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000573
Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000423
Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000350
Coordinated circadian timing through the integration of local inputs in Arabidopsis thaliana
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000407
Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000414
Mechanical stiffness of reconstituted actin patches correlates tightly with endocytosis efficiency
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000500
Environment-dependent pleiotropic effects of mutations on the maximum growth rate r and carrying capacity K of population growth
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000121
A photoactivatable crosslinking system reveals protein interactions in the Toxoplasma gondii inner membrane complex
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000475
Insulin resistance disrupts epithelial repair and niche-progenitor Fgf signaling during chronic liver injury
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.2006972
Staying awake to stay alive: A circuit controlling starvation-induced waking
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000199
A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000185
HSP-4/BiP expression in secretory cells is regulated by a developmental program and not by the unfolded protein response
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000196
Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
来源期刊：PLOS BiologyDOI：10.2210/PDB6JHQ/PDB
Evolution of a family of molecular Rube Goldberg contraptions
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000405
Correction: Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000176
Caveat Pre-Emptor: Contextualising peer review and publication
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000234
Perceptual uncertainty
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000430
Correction: Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000514
A 3D-printed hand-powered centrifuge for molecular biology
来源期刊：PLoS BiologyDOI：10.1371/journal.pbio.3000251
