The Physiological Genomics publishes original papers, reviews and rapid reports in a wide area of research focused on uncovering the links between genes and physiology at all levels of biological organization. Articles on topics ranging from single genes to the whole genome and their links to the physiology of humans, any model organism, organ, tissue or cell are welcome. Areas of interest include complex polygenic traits preferably of importance to human health and gene-function relationships of disease processes. Specifically, the Journal has dedicated Sections focused on genome-wide association studies (GWAS) to function, cardiovascular, renal, metabolic and neurological systems, exercise physiology, pharmacogenomics, clinical, translational and genomics for precision medicine, comparative and statistical genomics and databases. For further details on research themes covered within these Sections, please refer to the descriptions given under each Section.
《生理基因组学》发表原创论文、评论和快速报告，涉及广泛的研究领域，重点是揭示基因和生理学之间在生物组织的各个层面上的联系。文章的主题范围从单基因到整个基因组及其与人类生理学的联系，任何模式生物，器官，组织或细胞是受欢迎的。感兴趣的领域包括优选对人类健康重要的复杂多基因性状和疾病过程的基因-功能关系。具体而言，该杂志设有专门的章节，重点关注功能、心血管、肾脏、代谢和神经系统的全基因组关联研究（GWAS）、运动生理学、药物基因组学、精准医学的临床、转化和基因组学、比较和统计基因组学和数据库。有关这些章节所涵盖的研究主题的进一步详情，请参阅各章节下的说明。
Identification of molecular signatures of cystic fibrosis disease status with plasma-based functional genomics.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00109.2018
Gene expression effects of lithium and valproic acid in a serotonergic cell line.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00069.2018
Germ-line genetic variation in the immunoglobulin heavy chain creates stroke suceptibility in the spontaneously hypertensive rat.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00054.2019
Aging, melatonin biosynthesis, and circadian clockworks in the gastrointestinal system of the laboratory mouse.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00095.2018
Clock gene expression is altered in veterans with sleep apnea.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00091.2018
Differential circRNA expression profiles in latent human cytomegalovirus infection and validation using clinical samples.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00096.2018
5-HT does not lower blood pressure in the 5-HT7 knock-out rat.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00031.2019
Profiling expression changes of genes associated with temperature and sex during high temperature-induced masculinization in the Nile tilapia brain.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00117.2018
microRNA-146a-5p association with the cardiometabolic disease risk factor TMAO.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00079.2018
Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00127.2018
Whole Genome Sequencing and Novel Candidate Genes for CAKUT and Altered Nephrogenesis in the HSRA Rat.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00112.2019
Profiling the rainbow trout hepatic miRNAome under diet-induced hyperglycemia.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00032.2019
Microarray profiling analysis and validation of novel long noncoding RNAs and mRNAs as potential biomarkers and their functions in atherosclerosis
来源期刊：Physiological GenomicsDOI：10.1152/physiolgenomics.00077.2019
A role for the mammalian female reproductive tract microbiome in pregnancy outcomes.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00045.2019
Transcriptomic Signature of Gut Microbiome-Contacting Cells in Colon of Spontaneously Hypertensive Rats.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00087.2019
Vertical selection for nuclear and mitochondrial genomes shapes gut microbiota and modifies risks for complex diseases.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00089.2019
Characterisation of eQTLs associated with androstenone by RNA sequencing in porcine testis.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00125.2018
Activation of the cannabinoid receptor 2 increases renal perfusion.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00001.2019
Different blood pressure responses in hypertensive rats following chemerin mRNA inhibition in dietary high fat compared to dietary high salt conditions.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00050.2019
Cardiac endothelial cell transcriptome in neonatal, adult, and remodeling hearts.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00002.2019
Epigenomic mechanisms of alcohol-induced impaired differentiation of skeletal muscle stem cells; role of Class IIA histone deacetylases.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00043.2019
Genome-wide association study identifies the PLAG1-OXR1 region on BTA14 for carcass meat yield in cattle.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00112.2018
Genetic and genomic evidence for an important role of the Na+/H+ exchanger 3 in blood pressure regulation and angiotensin II-induced hypertension.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00122.2018
Associations of osteopontin and NT-proBNP with circulating miRNA levels in acute coronary syndrome
来源期刊：Physiological GenomicsDOI：10.1152/physiolgenomics.00033.2019
BMI-associated gene variants in FTO and cardiometabolic and brain disease: obesity or pleiotropy?
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00040.2019
Genome-wide association study for backfat thickness at 100 kg and loin muscle thickness in domestic pigs based on genotyping by sequencing.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00008.2019
RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00066.2019
Human genotyping and an experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00049.2018
Intra- and inter-generational changes in the cortical DNA methylome in response to therapeutic intermittent hypoxia in mice.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00094.2019
Arrdc2 and Arrdc3 elicit divergent changes in gene expression in skeletal muscle following anabolic and catabolic stimuli.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00007.2019
Multiomics Analyses of Vesicular Transport Pathway-Specific Transcripts and Proteins in Ovine Amnion: Responses to Altered Intramembranous Transport.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00003.2019
Toll-like receptor 4-mediated respiratory syncytial virus disease and lung transcriptomics in differentially susceptible inbred mouse strains.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00101.2019
Interactions of bile acids and the gut microbiota: learning from the differences in Clostridium difficile infection between children and adults.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00034.2019
Metabolic fitness in relation to genetic variation and leukocyte DNA methylation.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00077.2018
Early transcriptomic responses associated with the membrane-initiated action of cortisol in the skeletal muscle of rainbow trout (Oncorhynchus mykiss).
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00042.2019
LncRNA IUR downregulates ZEB1 by upregulating miR-200 to inhibit prostate carcinoma.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00062.2019
Effect of MMP-9 gene knockout on retinal vascular form and function.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00041.2019
Computational deconvolution of synovial tissue cellular composition: presence of adipocytes in synovial tissue decreased during arthritis pathogenesis and progression.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00009.2019
Subfornical organ insulin receptors tonically modulate cardiovascular and metabolic function.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00021.2019
Identification of suitable reference microRNA for qPCR analysis in pediatric inflammatory bowel disease.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00126.2018
Functional genomic characterization of the FTO locus in African Americans
来源期刊：Physiological GenomicsDOI：10.1152/PHYSIOLGENOMICS.00057.2019
PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00101.2018
ATP2A2 rs3026468 does not associate with quadriceps contractile properties and acute muscle potentiation in humans
来源期刊：Physiological GenomicsDOI：10.1152/physiolgenomics.00085.2018
Cross-talk between mineral metabolism and meat quality: a systems biology overview.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00072.2019
Profiling solute-carrier transporters in key metabolic tissues during the postpartum evolution of mammary epithelial cells from non-secretory to secretory.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00058.2019
Quantitative Trait Loci (QTL) associated with angiotensin II and high-salt diet induced acute decompensated heart failure in Balb/CJ mice.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00017.2019
Tissue-dependent DNA methylation of carp uncoupling protein 1 promoter.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00024.2019
Correlation of gene expression and clinical parameters identifies a set of genes reflecting LV systolic dysfunction and morphological alterations.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00111.2018
Breakdown of Multiple Sclerosis Genetics to Identify an Integrated Disease Network and Potential Variant Mechanisms.
来源期刊：Physiological genomicsDOI：10.1152/physiolgenomics.00120.2018
