Pharmacological Reviews presents important review articles covering the broad spectrum of pharmacological research. Topics covered have included biochemical and cellular pharmacology, drug metabolism and disposition, renal pharmacology, neuropharmacology, behavioral pharmacology, clinical pharmacology, and toxicology. IUPHAR nomenclature reports are published here.
药理学综述提供了涵盖广泛药理学研究的重要综述文章。所涉及的主题包括生化和细胞药理学、药物代谢和处置、肾脏药理学、神经药理学、行为药理学、临床药理学和毒理学。IUPHAR命名报告在此发布。
Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.017129
REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.017160
A Practical Review of Proteasome Pharmacology
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.117.015370
Gut Reactions: Breaking Down Xenobiotic–Microbiome Interactions
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.015768
Biased Receptor Signaling in Drug Discovery
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.016790
The Purinergic System as a Pharmacological Target for the Treatment of Immune-Mediated Inflammatory Diseases
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.117.014878
Harnessing Ion-Binding Sites for GPCR Pharmacology
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.119.017863
Cell Volume-Activated and Volume-Correlated Anion Channels in Mammalian Cells: Their Biophysical, Molecular, and Pharmacological Properties
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.015917
Core Outcome Measures in Preclinical Assessment of Candidate Analgesics
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.017210
Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.017178
Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.016253
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.119.017533
5-HT3 Receptor Antagonists in Neurologic and Neuropsychiatric Disorders: The Iceberg Still Lies beneath the Surface
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.015487
Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.117.013995
Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.016816
Beyond the Ligand: Extracellular and Transcellular G Protein–Coupled Receptor Complexes in Physiology and Pharmacology
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.119.018044
Challenges and Opportunities for Childhood Cancer Drug Development
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.016972
Druggable Transcriptional Networks in the Human Neurogenic Epigenome
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.119.017681
Dose-Response-Time Data Analysis: An Underexploited Trinity
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.015750
A Pharmacological Perspective on the Study of Taste
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.015974
Role of Voltage-Gated Sodium Channels in the Mechanism of Ether-Induced Unconsciousness
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.016592
Cognitive Effects of MDMA in Laboratory Animals: A Systematic Review Focusing on Dose
来源期刊:Pharmacological ReviewsDOI:10.1124/pr.118.017087