Pharmacological Research publishes cutting-edge articles in biomedical sciences to cover a broad range of topics that move the pharmacological field forward. We provide a venue through which specialists across disciplines can rapidly exchange information in health sciences that pertains to modern pharmacological topics. The journal publishes articles on molecular, biochemical, translational, and clinical research (including clinical trials); it is proud of its rapid publication of accepted papers that comprises a dedicated, fast acceptance and publication track for high profile articles.
药理学研究出版生物医学领域的前沿文章,涵盖推动药理学领域向前发展的广泛主题。我们提供了一个平台,通过这个平台,跨学科的专家可以快速交流与现代药理学主题相关的健康科学信息。该杂志发表有关分子、生物化学、转化和临床研究(包括临床试验)的文章;它以其快速出版被接受的论文而自豪,包括一个专门的、快速的接受和出版高知名度文章的轨道。
Cyclin-dependent protein serine/threonine kinase inhibitors as anticancer drugs.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2018.11.035
Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.02.009
Clinical evidence on the effects of saffron (Crocus sativus L.) on cardiovascular risk factors: A systematic review meta‐analysis
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.11.038
The therapeutic role of long non‐coding RNAs in human diseases: A focus on the recent insights into autophagy
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.02.010
Hydrogen sulfide stabilizes atherosclerotic plaques in apolipoprotein E knockout mice.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.04.006
The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104332
Preclinical and clinical results regarding the effects of a plant-based antidiabetic formulation versus well established antidiabetic molecules.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104522
Topoisomerase inhibitors: pharmacology and emerging nanoscale delivery systems.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104551
Dysregulation of the Hippo pathway signaling in aging and cancer
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.03.018
β-blockers: their new life from hypertension to cancer and migraine.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104587
Unveiling the guidance heterogeneity for genome-informed drug treatment interventions among regulatory bodies and research consortia.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104590
Straight to the heart: Pleiotropic antiarrhythmic actions of oral anticoagulants.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104257
Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.04.021
Saponins from Clematis mandshurica Rupr. regulates gut microbiota and its metabolites during alleviation of collagen-induced arthritis in rats.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104459
Rev‐erb&agr; activation down‐regulates hepatic Pck1 enzyme to lower plasma glucose in mice
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.01.010
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104387
Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG).
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.02.007
Functional biological pacemaker generation by T‐Box18 protein expression via stem cell and viral delivery approaches in a murine model of complete heart block
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.01.034
Multi-dimensional Roles of Ketone Bodies in Cancer Biology: Opportunities for Cancer Therapy.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104500
A novel class of cardioprotective small-molecule PTP inhibitors.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104548
ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4‐nerolidylcathecol (4‐NC)
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.12.006
Inhibition of class I HDACs attenuates renal interstitial fibrosis in a murine model
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.02.011
Cognitive enhancers as a treatment for heroin relapse and addiction
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.01.025
Oleoylethanolamide inhibits glial activation via moudulating PPAR&agr; and promotes motor function recovery after brain ischemia
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.01.027
Autophagy inhibition plays a protective role against 3, 4‐methylenedioxymethamphetamine (MDMA)‐induced loss of serotonin transporters and depressive‐like behaviors in rats
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.02.026
Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104591
Pharmacological preconditioning with the cellular stress inducer thapsigargin protects against experimental sepsis
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.12.017
Mahanine, A dietary phytochemical, represses mammary tumor burden in rat and inhibits subtype regardless breast cancer progression through suppressing self-renewal of breast cancer stem cells.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104330
Role of transient receptor potential ankyrin 1 (TRPA1) on nociception caused by a murine model of breast carcinoma.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104576
Mitochondrial carnitine palmitoyltransferase 2 is involved in Nε-(carboxymethyl)-lysine-mediated diabetic nephropathy.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104600
Targeting STATs in neuroinflammation: The road less traveled!
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.12.004
Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.11.031
Programming Changes in GLUT1 Mediated the Accumulation of AGEs and Matrix Degradation in the Articular Cartilage of Female Adult Rats after Prenatal Caffeine Exposure.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104555
Use of oral contraceptives and risk of ulcerative colitis – A systematic review and meta‐analysis
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2018.11.036
Identification of an IKKβ inhibitor for inhibition of inflammation in vivo and in vitro.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104440
Lead Bioactive Compounds of Aloe vera as Potential Anticancer Agent.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104416
Megalin: A Bridge Connecting Kidney, the Renin-angiotensin System, and Atherosclerosis.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104537
Destabilization of ROR1 enhances activity of ibrutinib against chronic lymphocytic leukemia in vivo.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104512
Plumbagin inhibits cancer stem-like cells, angiogenesis and suppresses cell proliferation and invasion by targeting Wnt/β-catenin pathway in endocrine resistant breast cancer.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104517
An oral 2-hydroxypropyl-β-cyclodextrin-loaded spirooxindole-pyrrolizidine derivative restores p53 activity via targeting MDM2 and JNK1/2 in hepatocellular carcinoma.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104400
Growth hormone-releasing hormone (GHRH) deficiency promotes inflammation-associated carcinogenesis.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104614
Striatal morphological and functional alterations induced by prenatal alcohol exposure
来源期刊:Pharmacological ResearchDOI:10.1016/j.phrs.2019.02.022
Sex-differences in factors and outcomes associated with adherence to statin therapy in primary care: need for customisation strategies.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104514
N-octanoyl dopamine is superior to dopamine in protecting graft contractile function when administered to the heart transplant recipients from brain-dead donors.
来源期刊:Pharmacological researchDOI:10.1016/j.phrs.2019.104503