The Pharmacogenomics Journal is a print and electronic journal, which is dedicated to the rapid publication of original research on pharmacogenomics and its clinical applications.Key areas of coverage include:Personalized medicineEffects of genetic variability on drug toxicity and efficacyIdentification and functional characterization of polymorphisms relevant to drug actionPharmacodynamic and pharmacokinetic variations and drug efficacyIntegration of new developments in the genome project and proteomics into clinical medicine, pharmacology, and therapeuticsClinical applications of genomic scienceIdentification of novel genomic targets for drug developmentPotential benefits of pharmacogenomics.
《药物基因组学杂志》是一本印刷和电子期刊,致力于快速发表药物基因组学及其临床应用的原创研究。主要报道领域包括:个性化药物遗传变异对药物毒性和疗效的影响与药物作用相关的多态性的鉴定和功能表征药效学和药代动力学变异以及药物疗效将基因组计划和蛋白质组学的新进展整合到临床医学、药理学和治疗学中基因组科学的临床应用药物开发的新基因组靶点的鉴定药物基因组学的潜在益处。
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0067-3
Cost-effectiveness analysis of multigene expression profiling assays to guide adjuvant therapy decisions in women with invasive early-stage breast cancer
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0089-x
Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0113-1
Drug–drug–gene interactions and adverse drug reactions
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0122-0
Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0069-1
Predicting antidepressant treatment outcome based on socioeconomic status and citalopram dose
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0080-6
A single nucleotide polymorphism of IL6-receptor is associated with response to tocilizumab in rheumatoid arthritis patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0072-6
Towards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0096-y
Identification of SAMD9L as a susceptibility locus for intravenous immunoglobulin resistance in Kawasaki disease by genome-wide association analysis
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0085-1
Dissecting the m6A methylation affection on afatinib resistance in non-small cell lung cancer
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0110-4
Pharmacogenetic interactions in amyotrophic lateral sclerosis: a step closer to a cure?
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0111-3
Variants in vincristine pharmacodynamic genes involved in neurotoxicity at induction phase in the therapy of pediatric acute lymphoblastic leukemia
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0081-5
Gender based differences, pharmacogenetics and adverse events in chronic pain management
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0118-9
Precision dosing of warfarin: open questions and strategies
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0083-3
Opportunities for pharmacists to integrate pharmacogenomics into clinical practice
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0119-8
Influence of CYP2B6 activity score on the pharmacokinetics and safety of single dose efavirenz in healthy volunteers
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0103-3
Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study
来源期刊:The pharmacogenomics journalDOI:10.1038/s41397-019-0125-x
Genetic Polymorphisms Associated with Reactive Oxygen Species and Blood Pressure Regulation
来源期刊:The pharmacogenomics journalDOI:10.1038/s41397-019-0082-4
Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0068-2
Genetic association between CD96 locus and immunogenicity to anti-TNF therapy in Crohn’s disease
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0090-4
OPRM1, OPRK1, and COMT genetic polymorphisms associated with opioid effects on experimental pain: a randomized, double-blind, placebo-controlled study
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0131-z
Candidate gene analyses for acute pain and morphine analgesia after pediatric day surgery: African American versus European Caucasian ancestry and dose prediction limits
来源期刊:The pharmacogenomics journalDOI:10.1038/s41397-019-0074-4
HLA-DRB1*07:01 and lapatinib-induced hepatotoxicity: a systematic review and meta-analysis
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0092-2
Predictive genetic biomarkers for the efficacy of methotrexate in rheumatoid arthritis: a systematic review
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0098-9
An economic model of the cost-utility of pre-emptive genetic testing to support pharmacotherapy in patients with major depression in primary care
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0070-8
Warfarin loading dose guided by pharmacogenetics is effective and safe in cardioembolic stroke patients – a randomized, prospective study
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0066-4
Genetic contribution to lipid target achievement with statin therapy: a prospective study
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0136-7
Meta-analysis of the associations of CYP2B6-516G>T polymorphisms with efavirenz-induced central nervous system side effects and virological outcome in HIV-infected adults
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0112-2
A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0101-5
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0116-y
Ketamine in seizure management and future pharmacogenomic considerations
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0120-2
Proteomic analysis to define predictors of treatment response to adalimumab or methotrexate in rheumatoid arthritis patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0139-4
The efficacy of interferon-beta therapy in multiple sclerosis patients: investigation of the RORA gene as a predictive biomarker
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0114-0
CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0117-x
Pharmacogenomic phase transition from personalized medicine to patient-centric customized delivery
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0135-8
Is a pharmacogenomic panel useful to estimate the risk of oxaliplatin-related neurotoxicity in colorectal cancer patients?
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0078-0
PACSIN2 rs2413739 influence on thiopurine pharmacokinetics: validation studies in pediatric patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0130-0
Genome-Wide Meta-analysis of Variant-by-Diuretic Interactions as Modulators of Lipid Traits in Persons of European and African Ancestry
来源期刊:The pharmacogenomics journalDOI:10.1038/s41397-019-0132-y
Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0087-z
A GALNT14 rs9679162 genotype-guided therapeutic strategy for advanced hepatocellular carcinoma: systemic or hepatic arterial infusion chemotherapy
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0106-0
An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0126-9
Association between endothelial nitric oxide synthase (NOS3) rs2070744 and the risk for migraine
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0133-x
Folyl polyglutamate synthethase (FPGS) gene polymorphisms may influence methotrexate adverse events in South Indian Tamil Rheumatoid Arthritis patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0097-x
A genome-wide association study of tramadol metabolism from post-mortem samples
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0088-y
Correction: The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0073-5
Correction: Polymorphisms at phase I-metabolizing enzyme and\n hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis\n patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0084-2
HLA-A*02:01 allele is associated with tanshinone-induced cutaneous drug reactions in Chinese population
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0121-1
Prospective validation of the International Warfarin Pharmacogenetics Consortium algorithm in high-risk elderly people (VIALE study)
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0129-6
Analysis of galanin receptor GALR2 in multiple sclerosis
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0100-6
Pharmacogenetic determinants of kidney-associated urinary and serum abnormalities in antiretroviral-treated HIV-positive patients
来源期刊:The Pharmacogenomics JournalDOI:10.1038/s41397-019-0109-x