Although laboratory and clinical cancer research need to be closely linked, observations at the basic level often remain removed from medical applications. This journal works to accelerate the translation of experimental results into the clinic, and back again into the laboratory for further investigation. The fundamental purpose of this effort is to advance clinically-relevant knowledge of cancer, and improve the outcome of prevention, diagnosis and treatment of malignant disease. The journal publishes significant clinical studies from cancer programs around the world, along with important translational laboratory findings, mini-reviews (invited and submitted) and in-depth discussions of evolving and controversial topics in the oncology arena. A unique feature of the journal is a new section which focuses on rapid peer-review and subsequent publication of short reports of phase 1 and phase 2 clinical cancer trials, with a goal of insuring that high-quality clinical cancer research quickly enters the public domain, regardless of the trial’s ultimate conclusions regarding efficacy or toxicity.
虽然实验室和临床癌症研究需要密切联系,但基础水平的观察往往仍然远离医学应用。该杂志致力于加速将实验结果转化为临床,并再次转化为实验室进行进一步研究。这项工作的基本目的是提高癌症的临床相关知识,并改善恶性疾病的预防、诊断和治疗结果。该杂志发表来自世界各地癌症项目的重要临床研究,沿着重要的转化实验室发现、小型综述(邀请和提交)和肿瘤竞技场不断发展和有争议的主题的深入讨论。该杂志的一个独特之处是一个新的部分,重点是快速同行评审和随后发表的短期报告的第一和第二阶段的临床癌症试验,以确保高质量的临床癌症研究迅速进入公共领域的目标,无论试验的最终结论是关于疗效或毒性。
Important Clinical Factors in Sequential Therapy Including Lenvatinib against Unresectable Hepatocellular Carcinoma
来源期刊:OncologyDOI:10.1159/000501281
Correlation between Early Tumor Marker Response and Imaging Response in Patients with Advanced Hepatocellular Carcinoma Treated with Lenvatinib
来源期刊:OncologyDOI:10.1159/000499715
The Role of Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio, and Platelets in the Prognosis of Metastatic Renal Cell Carcinoma
来源期刊:OncologyDOI:10.1159/000498943
Early Relative Change in Hepatic Function with Lenvatinib for Unresectable Hepatocellular Carcinoma
来源期刊:OncologyDOI:10.1159/000502095
Stool-Based miR-92a and miR-144* as Noninvasive Biomarkers for Colorectal Cancer Screening
来源期刊:OncologyDOI:10.1159/000500639
A Phase 2 Study of PCI-27483, a Factor VIIa Inhibitor in Combination with Gemcitabine for Advanced Pancreatic Cancer
来源期刊:OncologyDOI:10.1159/000495988
Tropomyosin-Related Kinase Receptor and Neurotrophin Expression in Cutaneous Melanoma Is Associated with a Poor Prognosis and Decreased Survival
来源期刊:OncologyDOI:10.1159/000499384
Prognostic Impact of Microsatellite Instability in Asian Gastric Cancer Patients Enrolled in the ARTIST Trial
来源期刊:OncologyDOI:10.1159/000499628
Association of Hand-Foot Skin Reaction with Regorafenib Efficacy in the Treatment of Metastatic Colorectal Cancer
来源期刊:OncologyDOI:10.1159/000495989
Dental Cone Beam Computed Tomography in Children: Clinical Effectiveness and Cancer Risk due to Radiation Exposure
来源期刊:OncologyDOI:10.1159/000497059
Use of Complementary and Alternative Medicines among Cancer Patients: A Single-Center Study
来源期刊:OncologyDOI:10.1159/000499629
Advocacy for a New Oncology Research Paradigm: The Model of Bevacizumab in Triple-Negative Breast Cancer in a French Cohort Study
来源期刊:OncologyDOI:10.1159/000499583
Predicted Markers of Overall Survival in Pancreatic Cancer Patients Receiving Dendritic Cell Vaccinations Targeting WT1
来源期刊:OncologyDOI:10.1159/000500359
Co-Occurring Symptoms Contribute to Persistent Fatigue in Prostate Cancer
来源期刊:OncologyDOI:10.1159/000494620
Nectin-1 Expression in Colorectal Cancer: Is There a Group of Patients with High Risk for Early Disease Recurrence?
来源期刊:OncologyDOI:10.1159/000499569
Cetuximab in Pancreatic Cancer Therapy: A Systematic Review and Meta-Analysis
来源期刊:OncologyDOI:10.1159/000502844
Metachronous and Synchronous Cancers in Patients with Neuroendocrine Tumors
来源期刊:OncologyDOI:10.1159/000502384
Ramucirumab and Paclitaxel Administered Every 2 Weeks (mRAINBOW Regimen) in Advanced Gastroesophageal Adenocarcinoma
来源期刊:OncologyDOI:10.1159/000496978
Unique Patterns of Distant Metastases in HPV-Positive Head and Neck Cancer
来源期刊:OncologyDOI:10.1159/000504651
The Prognostic Value of the Pretreatment Neutrophil/Lymphocyte Ratio in Patients with Glioblastoma Multiforme Brain Tumors: A Retrospective Cohort Study of Patients Treated with Combined Modality Surgery, Radiation Therapy, and Temozolomide Chemotherapy
来源期刊:OncologyDOI:10.1159/000500926
Impact of Age on Long-Term Survival in Patients with Esophageal Cancer Who Underwent Transthoracic Esophagectomy
来源期刊:OncologyDOI:10.1159/000500604
The Evolving Arena of Ovarian Cancer Maintenance Therapy
来源期刊:OncologyDOI:10.1159/000501618
Landscape of Immune-Related Pneumonitis in Cancer Patients with Asthma Being Treated with Immune Checkpoint Blockade
来源期刊:OncologyDOI:10.1159/000503566
Local Therapy in Advanced Cholangiocarcinoma: A Review of Current Endoscopic, Medical, and Oncologic Treatment Options
来源期刊:OncologyDOI:10.1159/000500832
Influence of the New FIGO Classification for Cervical Cancer on Patient Survival: A Retrospective Analysis of 265 Histologically Confirmed Cases with FIGO Stages IA to IIB
来源期刊:OncologyDOI:10.1159/000503149
Chemotherapy Following PD-1 Inhibitor Blockade in Patients with Unresectable Stage III/Stage IV Metastatic Melanoma: A Single Academic Institution Experience
来源期刊:OncologyDOI:10.1159/000504578
A Phase II Study of Cisplatin Plus Gemcitabine followed by Maintenance Gemcitabine for Advanced Squamous Non-Small-Cell Lung Cancer: Kyoto Thoracic Oncology Research Group 1302
来源期刊:OncologyDOI:10.1159/000501967
Racial Disparities, Outcomes, and Surgical Utilization among Hispanics with Esophageal Cancer: A Surveillance, Epidemiology, and End Results Program Database Analysis
来源期刊:OncologyDOI:10.1159/000499716
Molecular Barcode Sequencing for Highly Sensitive Detection of Circulating Tumor DNA in Patients with Esophageal Squamous Cell Carcinoma
来源期刊:OncologyDOI:10.1159/000504808
Prophylactic Effect of Premedication with Intravenous Magnesium on Renal Dysfunction in Preoperative Cisplatin-Based Chemotherapy for Esophageal Cancer
来源期刊:OncologyDOI:10.1159/000501966
Trastuzumab Emtansine (T-DM1) Plus S-1 in Patients with Trastuzumab-Pretreated HER2-Positive Advanced or Metastatic Breast Cancer: A Phase Ib Study
来源期刊:OncologyDOI:10.1159/000497276
Expression of c-Met in Primary and Recurrent Hepatocellular Carcinoma
来源期刊:OncologyDOI:10.1159/000504806
Recognition and Treatment of Adrenal Insufficiency Secondary to Abiraterone: A Case Report and Literature Review
来源期刊:OncologyDOI:10.1159/000501640
Drug Management in End-of-Life Hospitalized Palliative Care Cancer Patients: The RHESO Cohort Study
来源期刊:OncologyDOI:10.1159/000500783
Immuno-Oncological Treatment and Tumor Mass in Non-Small Cell Lung Cancer: Case-Control Analysis of Overall Survival in Routine Clinical Practice
来源期刊:OncologyDOI:10.1159/000500885
Role of 18F-Fluorodeoxyglucose Positron Emission Tomography or Positron Emission Tomography/Computed Tomography for the Detection of Recurrent Disease after Treatment of Malignant Melanoma
来源期刊:OncologyDOI:10.1159/000501398
Risk of Pneumonitis with the Use of Different Immune Checkpoint Inhibitors in a Mexican Population
来源期刊:OncologyDOI:10.1159/000497405
Expressiveness of Bone Markers in Breast Cancer with Bone Metastases
来源期刊:OncologyDOI:10.1159/000500675
Intrahepatic Oxaliplatin and Systemic 5-FU +/– Cetuximab in Chemo-Naïve Patients with Liver Metastases from Colorectal Cancer
来源期刊:OncologyDOI:10.1159/000499314
Clinically Node-Negative Parotid Gland Cancers: Prognostic Factors of Survival and Surgical Extent
来源期刊:OncologyDOI:10.1159/000503580
Hemiablation of Localized Prostate Cancer by High-Intensity Focused Ultrasound: A Series of 35 Cases
来源期刊:OncologyDOI:10.1159/000499739
Comparative Study of the Safety and Efficacy of First-Line Cisplatin and Carboplatin Chemotherapy in Elderly Patients with Metastatic Urothelial Carcinoma
来源期刊:OncologyDOI:10.1159/000504393
Radiographic Assessment of Objective Responses Using the ITMIG-Modified Criteria in Thymic Carcinoma
来源期刊:OncologyDOI:10.1159/000501104
Impact of Cigarette Smoking and Head and Neck Squamous Cell Carcinoma on Circulating Inflammatory Biomarkers
来源期刊:OncologyDOI:10.1159/000502651
Prognostic Factors in HER2-Positive Primary Breast Cancer Patients Treated Using Neoadjuvant Chemotherapy Plus Trastuzumab
来源期刊:OncologyDOI:10.1159/000502910
A Phase I Study of Neoadjuvant Capecitabine, Oxaliplatin, and Irinotecan (XELOXIRI) in Patients with Locally Advanced Rectal Cancer
来源期刊:OncologyDOI:10.1159/000500677
Vinflunine in Metastatic Urothelial Carcinoma of the Bladder in Progression after a Platinum-Containing Regimen
来源期刊:OncologyDOI:10.1159/000502116
Diffuse Hepatic Infiltration by Metastatic Melanoma.
来源期刊:OncologyDOI:10.46883/onc.2020.3307.0295
Impact of the Type of Analgesic Therapy on Postsurgical Complications of Patients with Kidney Cancer Undergoing Nephrectomy
来源期刊:OncologyDOI:10.1159/000504258
Clinical Implications of Decreased Computed Tomography Value after Ramucirumab in Advanced Gastric Cancer
来源期刊:OncologyDOI:10.1159/000500326