Neurobiology of Disease is a major international journal at the interface between basic and clinical neuroscience. The journal provides a forum for the publication of top quality research papers on: molecular and cellular definitions of disease mechanisms, the neural systems and underpinning behavioral disorders, the genetics of inherited neurological and psychiatric diseases, nervous system aging, and findings relevant to the development of new therapies.
《疾病神经生物学》是一本基础和临床神经科学接口的主要国际期刊。该杂志提供了一个论坛，发表高质量的研究论文：疾病机制的分子和细胞定义、神经系统和基础行为障碍、遗传性神经和精神疾病的遗传学、神经系统老化以及与新疗法开发相关的发现。
TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunities
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.05.012
Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.09.023
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.04.005
Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer’s Disease: A longitudinal MRI study
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.11.010
Advances and considerations in AD tau-targeted immunotherapy
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.104707
The role of pallidum in the neural integrator model of cervical dystonia
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.01.011
Autism-associated Nf1 deficiency disrupts corticocortical and corticostriatal functional connectivity in human and mouse
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.104479
N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.01.007
Pridopidine protects neurons from mutant-huntingtin toxicity via the sigma-1 receptor
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.05.009
Inactivation of sphingosine-1-phosphate receptor 2 (S1PR2) decreases demyelination and enhances remyelination in animal models of multiple sclerosis
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.11.018
Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.005
Inhibition and oscillations in the human brain tissue in vitro
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.02.006
Increased anxiety-like behavior following circuit-specific catecholamine denervation in mice
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.01.009
Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.02.019
Cell injury and receptor expression in the epileptic human amygdala
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.12.017
Differential accumulation of Tau phosphorylated at residues Thr231, Ser262 and Thr205 in hippocampal interneurons and its modulation by Tau mutations (VLW) and amyloid-β peptide
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.12.006
Soluble tau aggregates inhibit synaptic long-term depression and amyloid β-facilitated LTD in vivo
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.022
ER responses play a key role in Swiss-Cheese/Neuropathy Target Esterase-associated neurodegeneration
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104520
Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.009
Targeting the glutamatergic system to counteract organophosphate poisoning: A novel therapeutic strategy
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.02.017
Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104542
Amyotrophic Lateral Sclerosis-associated GGGGCC repeat expansion promotes Tau phosphorylation and toxicity
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104493
Changes of dimension of EEG/ECoG nonlinear dynamics predict epileptogenesis and therapy outcomes
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.12.014
The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.024
High-frequency oscillations and focal seizures in epileptic rodents
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.12.016
The neurobiological basis for novel experimental therapeutics in dystonia
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104526
Modeling Alzheimer’s disease with human iPS cells: advancements, lessons, and applications
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104503
Endothelial cells promote excitatory synaptogenesis and improve ischemia-induced motor deficits in neonatal mice
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.10.006
Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.02.004
The α3 and α4 nicotinic acetylcholine receptor (nAChR) subunits in the brainstem medulla of sudden infant death syndrome (SIDS)
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.01.010
Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.02.021
Modified age-dependent expression of NaV1.6 in an ALS model correlates with motor cortex excitability alterations
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104532
From adagio to allegretto: The changing tempo of theta frequencies in epilepsy and its relation to interneuron function
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.02.009
Upregulation of tumor necrosis factor-alpha in the anterior cingulate cortex contributes to neuropathic pain and pain-associated aversion
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.04.012
Intracranial atherosclerotic disease
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2018.11.008
Opportunities in precision psychiatry using PET neuroimaging in psychosis
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.016
Small-molecule drug screening identifies drug Ro 31-8220 that reduces toxic phosphorylated tau in Drosophila melanogaster
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104519
Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104506
The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104486
Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104561
Autonomic dysfunction in Parkinson’s disease: Implications for pathophysiology, diagnosis, and treatment
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.104700
Neuropathological changes and cognitive deficits in rats transgenic for human mutant tau recapitulate human tauopathy
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.018
Glycogen synthase kinase 3 β activity is essential for Polo-like kinase 2- and Leucine-rich repeat kinase 2-mediated regulation of α-synuclein
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.104720
Smooth muscle cell-specific knockout of FBW7 exacerbates intracranial atherosclerotic stenosis
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104584
Nucleolin reorganization and nucleolar stress in Purkinje cells of mutant PCD mice
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.03.017
Cranial burr hole with erythropoietin administration induces reverse arteriogenesis from the enriched extracranium
来源期刊：Neurobiology of DiseaseDOI：10.1016/j.nbd.2019.104538
Metabolism, cognition, and the brain throughout life
来源期刊：Neurobiology of diseaseDOI：10.1016/j.nbd.2019.104698
