Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.Integrative genetic topics comprise, but are not limited to:-Genes in the pathology of human disease-Molecular analysis of simple and complex genetic traits-Cancer genetics-Agricultural genomics-Developmental genetics-Regulatory variation in gene expression-Strategies and technologies for extracting function from genomic data-Pharmacological genomics-Genome evolution-Nature Genetics
《自然遗传学》出版了最高质量的遗传学研究。它包括对人类和植物特征以及其他模式生物的遗传和功能基因组研究。目前的研究重点是常见和复杂疾病的遗传基础以及通过实验扰动研究的基因网络的功能机制、结构和进化。综合遗传学主题包括但不限于： -人类疾病病理学中的基因-简单和复杂遗传性状的分子分析-癌症遗传学-农业基因组学-发育遗传学-基因表达的调控变异-从基因组数据中提取功能的策略和技术-药理基因组学-基因组进化-自然遗传学
Opportunities and challenges for transcriptome-wide association studies
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0385-z
Durum wheat genome highlights past domestication signatures and future improvement targets
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0381-3
Gossypium barbadense and Gossypium hirsutum genomes provide insights into the origin and evolution of allotetraploid cotton
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0371-5
A catalog of genetic loci associated with kidney function from analyses of a million individuals
来源期刊：Nature GeneticsDOI：10.1038/S41588-019-0407-X
The genome sequence of segmental allotetraploid peanut Arachis hypogaea
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0405-z
The genome of cultivated peanut provides insight into legume karyotypes, polyploid evolution and crop domestication
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0402-2
Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0459-y
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0457-0
Exome sequencing highlights the role of wild-relative introgression in shaping the adaptive landscape of the wheat genome
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0382-2
Inferring whole-genome histories in large population datasets
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0483-y
High-throughput identification of human SNPs affecting regulatory element activity
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0455-2
Mutation of a histidine-rich calcium-binding-protein gene in wheat confers resistance to Fusarium head blight
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0426-7
Abundant associations with gene expression complicate GWAS follow-up
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0404-0
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0507-7
Loss of DUX causes minor defects in zygotic genome activation and is compatible with mouse development
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0418-7
A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0370-6
Genebank genomics bridges the gap between the conservation of crop diversity and plant breeding
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0443-6
Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0417-8
A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0489-5
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION
来源期刊：Nature geneticsDOI：10.1038/s41588-018-0334-2
Resequencing of 414 cultivated and wild watermelon accessions identifies selection for fruit quality traits
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0518-4
Similarity regression predicts evolution of transcription factor sequence specificity
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0411-1
Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0516-6
The impact of short tandem repeat variation on gene expression
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0521-9
Genome-wide stability of the DNA replication program in single mammalian cells
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0347-5
The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0412-0
Systematic characterization of BAF mutations provides insights into intra-complex synthetic lethalities in human cancers
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0477-9
Germline NPM1 mutations lead to altered rRNA 2’-O-methylation and cause dyskeratosis congenita
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0502-z
The mutational footprints of cancer therapies
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0525-5
Landscape of stimulation-responsive chromatin across diverse human immune cells
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0505-9
Inflated performance measures in enhancer–promoter interaction-prediction methods
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0434-7
Lack of detectable neoantigen depletion signals in the untreated cancer genome
来源期刊：Nature geneticsDOI：10.1038/s41588-019-0532-6
Reply to: Revisiting the origin of octoploid strawberry
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0544-2
Roadmap for a precision-medicine initiative in the Nordic region
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0391-1
From a database of genomes to a forest of evolutionary trees
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0492-x
A framework for tiered informed consent for health genomic research in Africa
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0520-x
Measuring intolerance to mutation in human genetics
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0383-1
Doubts about TMEM230 as a gene for parkinsonism
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0354-6
Author Correction: Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0422-y
Author Correction: Assembly of a pan-genome from deep sequencing of 910 humans of African descent
来源期刊：Nature GeneticsDOI：10.1038/s41588-018-0335-1
Publisher Correction: Multi-trait analysis of genome-wide association summary statistics using MTAG
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0444-5
Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0376-0
A call for global action for rare diseases in Africa
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0552-2
Reply to ‘Inflated performance measures in enhancer–promoter interaction-prediction methods’
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0452-5
Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0448-1
Publisher Correction: Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments
来源期刊：Nature GeneticsDOI：10.1038/s41588-018-0341-3
Author Correction: Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0388-9
Publisher Correction: Landscape of B cell immunity and related immune evasion in human cancers
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0437-4
Reply to ‘Reconciling disparate estimates of viral genetic diversity during human influenza infections’
来源期刊：Nature GeneticsDOI：10.1038/s41588-019-0486-8
Comparative genomics of the major parasitic worms
来源期刊：Nature GeneticsDOI：10.1038/s41588-018-0262-1
