Mammalian Genome focuses on the experimental, theoretical and technical aspects of genetics, genomics, epigenetics and systems biology in mouse, human and other mammalian species, with an emphasis on the relationship between genotype and phenotype, elucidation of biological and disease pathways as well as experimental aspects of interventions, therapeutics, and precision medicine. The journal aims to publish high quality original papers that present novel findings in all areas of mammalian genetic research as well as review articles on areas of topical interest. The journal will also feature commentaries and editorials to inform readers of breakthrough discoveries as well as issues of research standards, policies and ethics.
哺乳动物基因组学主要研究小鼠、人类和其他哺乳动物物种的遗传学、基因组学、表观遗传学和系统生物学的实验、理论和技术方面,重点研究基因型和表型之间的关系,阐明生物学和疾病途径,以及干预、治疗和精准医学的实验方面。该杂志旨在发表高质量的原创论文,介绍哺乳动物遗传学研究的所有领域的新发现,以及对热点领域的评论文章。该杂志还将刊登评论和社论,向读者介绍突破性的发现以及研究标准、政策和伦理问题。
Humanized mouse models of immunological diseases and precision medicine
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09796-2
New models for human disease from the International Mouse Phenotyping Consortium
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09804-5
Exploring the dark genome: implications for precision medicine
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09809-0
Amplification of lncRNA PVT1 promotes ovarian cancer proliferation by binding to miR-140
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09808-1
Treating Rett syndrome: from mouse models to human therapies
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09793-5
miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09817-0
Genome-wide scans identify known and novel regions associated with prolificacy and reproduction traits in a sub-Saharan African indigenous sheep (Ovis aries)
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09820-5
The guanine nucleotide exchange factor, Spata13, influences social behaviour and nocturnal activity
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09800-9
Liver size and lipid content differences between BALB/c and BALB/cJ mice on a high-fat diet are due, in part, to Zhx2
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09811-6
A high-density genetic map and molecular sex-typing assay for gerbils
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09799-z
Evidence for a de novo, dominant germ-line mutation causative of osteogenesis imperfecta in two Red Angus calves
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09794-4
Uses for humanised mouse models in precision medicine for neurodegenerative disease
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09807-2
Transposable element-mediated structural variation analysis in dog breeds using whole-genome sequencing
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09812-5
Closing the ‘phenotype gap’ in precision medicine: improving what we measure to understand complex disease mechanisms
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09810-7
Analysis and preliminary validation of the molecular mechanism of fat deposition in fatty and lean pigs by high-throughput sequencing
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09795-3
Chronic and age-dependent effects of the spongiform neurodegeneration-associated MGRN1 E3 ubiquitin ligase on mitochondrial homeostasis
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09802-7
Hepatic gene expression variations in response to high-fat diet-induced impaired glucose tolerance using RNAseq analysis in collaborative cross mouse population
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09816-1
Inbreeding depression causes reduced fecundity in Golden Retrievers
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09805-4
The dark genome and pleiotropy: challenges for precision medicine
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09813-4
Meeting report: 32nd international mammalian genome conference
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09797-1
The gut microbiota modulates differential adenoma suppression by B6/J and B6/N genetic backgrounds in ApcMin mice
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09814-3
Model validity for preclinical studies in precision medicine: precisely how precise do we need to be?
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09798-0
Genetic variation in thyroid folliculogenesis influences susceptibility to hypothyroidism-induced hearing impairment
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09792-6
Precision medicine and Mammalian Genome
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09801-8
Mice expressing the variant rs1143679 allele of ITGAM (CD11b) show impaired DC-mediated T cell proliferation
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09819-y
Allele substitution and dominance effects of CD166/ALCAM gene polymorphisms for endoparasite resistance and test-day traits in a small cattle population using logistic regression analyses
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09818-z
Crim1C140S mutant mice reveal the importance of cysteine 140 in the internal region 1 of CRIM1 for its physiological functions
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09822-3
The JAX Synteny Browser for mouse-human comparative genomics
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09821-4
Mouse model of the human serotonin transporter-linked polymorphic region
来源期刊:Mammalian GenomeDOI:10.1007/s00335-019-09815-2