mAbs is a multi-disciplinary journal dedicated to the art and science of antibody research and development. The journal has a strong scientific and medical focus, but also strives to serve a broader readership. The articles are thus of interest to scientists, clinical researchers, and physicians, as well as the wider mAb community, including our readers involved in technology transfer, legal issues, investment, strategic planning and the regulation of therapeutics.
mAbs是一本多学科期刊,致力于抗体研究和开发的艺术和科学。该杂志有很强的科学和医学重点,但也努力为更广泛的读者群服务。因此,科学家、临床研究人员和医生以及更广泛的mAb社区(包括我们的读者,涉及技术转让、法律的问题、投资、战略规划和治疗法规)对这些文章感兴趣。
Antibodies to watch in 2020
来源期刊:mAbsDOI:10.1080/19420862.2019.1703531
Structure, heterogeneity and developability assessment of therapeutic antibodies
来源期刊:mAbsDOI:10.1080/19420862.2018.1553476
Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms
来源期刊:mAbsDOI:10.1080/19420862.2018.1551044
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics
来源期刊:mAbsDOI:10.1080/19420862.2018.1544454
Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons
来源期刊:mAbsDOI:10.1080/19420862.2018.1551675
In vitro and in silico assessment of the developability of a designed monoclonal antibody library
来源期刊:mAbsDOI:10.1080/19420862.2018.1556082
Antigen binding allosterically promotes Fc receptor recognition
来源期刊:mAbsDOI:10.1080/19420862.2018.1522178
Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy
来源期刊:mAbsDOI:10.1080/19420862.2019.1629239
Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies
来源期刊:mAbsDOI:10.1080/19420862.2019.1574521
Rapid single B cell antibody discovery using nanopens and structured light
来源期刊:mAbsDOI:10.1080/19420862.2019.1624126
Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease
来源期刊:mAbsDOI:10.1080/19420862.2019.1624463
Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling
来源期刊:mAbsDOI:10.1080/19420862.2018.1525262
Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
来源期刊:mAbsDOI:10.1080/19420862.2019.1602459
Modulating cell culture oxidative stress reduces protein glycation and acidic charge variant formation
来源期刊:mAbsDOI:10.1080/19420862.2018.1537533
Antibody-drug conjugates targeting TROP-2 and incorporating SN-38: A case study of anti-TROP-2 sacituzumab govitecan
来源期刊:mAbsDOI:10.1080/19420862.2019.1632115
Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity
来源期刊:mAbsDOI:10.1080/19420862.2019.1616506
The first World Health Organization International Standard for infliximab products: A step towards maintaining harmonized biological activity
来源期刊:mAbsDOI:10.1080/19420862.2018.1532766
Evolution of a comprehensive, orthogonal approach to sequence variant analysis for biotherapeutics
来源期刊:mAbsDOI:10.1080/19420862.2018.1531965
Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies
来源期刊:mAbsDOI:10.1080/19420862.2019.1608143
Antibody repertoire analysis of mouse immunization protocols using microfluidics and molecular genomics
来源期刊:mAbsDOI:10.1080/19420862.2019.1583995
Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions
来源期刊:mAbsDOI:10.1080/19420862.2019.1599634
Controlled conductivity at low pH in Protein L chromatography enables separation of bispecific and other antibody formats by their binding valency
来源期刊:mAbsDOI:10.1080/19420862.2019.1583996
Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis
来源期刊:mAbsDOI:10.1080/19420862.2019.1654305
From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses
来源期刊:mAbsDOI:10.1080/19420862.2019.1589852
Investigation of pre-existing reactivity to biotherapeutics can uncover potential immunogenic epitopes and predict immunogenicity risk
来源期刊:mAbsDOI:10.1080/19420862.2019.1612699
Influence of the bispecific antibody IgG subclass on T cell redirection
来源期刊:mAbsDOI:10.1080/19420862.2019.1624464
Optimization of a calcium-dependent Protein A-derived domain for mild antibody purification
来源期刊:mAbsDOI:10.1080/19420862.2019.1662690
Monovalent TNF receptor 1-selective antibody with improved affinity and neutralizing activity
来源期刊:mAbsDOI:10.1080/19420862.2018.1524664
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
来源期刊:mAbsDOI:10.1080/19420862.2019.1625662
Structural characterization of monoclonal antibodies targeting C-terminal Ser404 region of phosphorylated tau protein
来源期刊:mAbsDOI:10.1080/19420862.2019.1574530
Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry
来源期刊:mAbsDOI:10.1080/19420862.2019.1668226
Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus
来源期刊:mAbsDOI:10.1080/19420862.2019.1627152
Using bispecific antibodies in forced degradation studies to analyze the structure–function relationships of symmetrically and asymmetrically modified antibodies
来源期刊:mAbsDOI:10.1080/19420862.2019.1618675
Half-life extension and non-human primate pharmacokinetic safety studies of i-body AD-114 targeting human CXCR4
来源期刊:mAbsDOI:10.1080/19420862.2019.1626652
Single cell-produced and in vitro-assembled anti-FcRH5/CD3 T-cell dependent bispecific antibodies have similar in vitro and in vivo properties
来源期刊:mAbsDOI:10.1080/19420862.2018.1551676
Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein.
来源期刊:mAbsDOI:10.2210/PDB6DCA/PDB
Engineering an anti-CD52 antibody for enhanced deamidation stability
来源期刊:mAbsDOI:10.1080/19420862.2019.1631117
Selection and characterization of FcϵRI phospho-ITAM specific antibodies
来源期刊:mAbsDOI:10.1080/19420862.2019.1632113
The impact of standard accelerated stability conditions on antibody higher order structure as assessed by mass spectrometry
来源期刊:mAbsDOI:10.1080/19420862.2019.1599632
A general platform for antibody purification utilizing engineered-micelles
来源期刊:mAbsDOI:10.1080/19420862.2019.1565749
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members.
来源期刊:mAbsDOI:10.2210/PDB6OKN/PDB
Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics
来源期刊:mAbsDOI:10.1080/19420862.2019.1612690
Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities
来源期刊:mAbsDOI:10.1080/19420862.2018.1550320
Connecting the sequence dots: shedding light on the genesis of antibodies reported to be designed in silico
来源期刊:mAbsDOI:10.1080/19420862.2019.1611172
Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics
来源期刊:mAbsDOI:10.1080/19420862.2019.1635865
Targets for MAbs: innovative approaches for their discovery & validation, LabEx MAbImprove 6th antibody industrial symposium, June 25-26, 2018, Montpellier, France
来源期刊:mAbsDOI:10.1080/19420862.2019.1612691
Elucidating heavy/light chain pairing preferences to facilitate the assembly of bispecific IgG in single cells
来源期刊:mAbsDOI:10.1080/19420862.2019.1640549
L445P mutation on heavy chain stabilizes IgG4 under acidic conditions
来源期刊:mAbsDOI:10.1080/19420862.2019.1631116
Identification and characterization of an IgG sequence variant with an 11 kDa heavy chain C-terminal extension using a combination of mass spectrometry and high-throughput sequencing analysis
来源期刊:mAbsDOI:10.1080/19420862.2019.1667740
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies
来源期刊:mAbsDOI:10.1080/19420862.2019.1686319