Molecular Systems Biology is an open access journal publishing high quality, cutting-edge research in the multidisciplinary areas of systems biology, genomics, synthetic biology and systems medicine. Molecular Systems Biology has a fair and transparent process (http://msb.embopress.org/about#Transparent%20Editorial%20Process) to rapidly publish important science. Anonymous referee reports and editorial correspondence are published alongside manuscripts as Review Process Files in the Transparent Process section online.
《分子系统生物学》是一本开放获取的期刊,发表系统生物学、基因组学、合成生物学和系统医学等多学科领域的高质量、前沿研究成果。分子系统生物学有一个公平透明的流程(http://msb.embopress.org/about#Transparent%20Editorial%20Process)来快速发表重要的科学成果。匿名评审报告和编辑通信与手稿一起作为审查过程文件在透明过程部分在线发布。
Current best practices in single‐cell RNA‐seq analysis: a tutorial
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188746
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188503
Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188793
Complex‐centric proteome profiling by SEC‐SWATH‐MS
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188438
Unraveling the hidden universe of small proteins in bacterial genomes
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188290
De novo gene signature identification from single‐cell RNA‐seq with hierarchical Poisson factorization
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188557
Evidence that the human cell cycle is a series of uncoupled, memoryless phases
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188604
Quantification and discovery of sequence determinants of protein‐per‐mRNA amount in 29 human tissues
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188513
Widespread inter‐individual gene expression variability in Arabidopsis thaliana
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188591
Wave patterns organize cellular protrusions and control cortical dynamics
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188585
INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188250
Multiplex transcriptional characterizations across diverse bacterial species using cell‐free systems
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198875
Enzyme promiscuity shapes adaptation to novel growth substrates
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188462
Defining the RNA interactome by total RNA‐associated protein purification
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188689
Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188584
Absolute quantification of translational regulation and burden using combined sequencing approaches
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188719
R2‐P2 rapid‐robotic phosphoproteomics enables multidimensional cell signaling studies
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199021
CRISPR screens are feasible in TP53 wild‐type cells
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188679
High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198849
Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188339
The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198831
Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacy
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198838
Temporal order and precision of complex stress responses in individual bacteria
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188470
netDx: interpretable patient classification using integrated patient similarity networks
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188497
Genome‐wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188323
p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188685
Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199002
The fitness cost and benefit of phase‐separated protein deposits
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20178075
Inaccuracy of the log‐rank approximation in cancer data analysis
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188754
Expanding the uses of genome‐scale models with protein structures
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188601
Measuring glycolytic flux in single yeast cells with an orthogonal synthetic biosensor
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199071
Paralog dependency indirectly affects the robustness of human cells
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198871
A solid‐phase transfection platform for arrayed CRISPR screens
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198983
Genetic screen of the yeast environmental stress response dynamics uncovers distinct regulatory phases
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198939
Antibody Fab‐Fc properties outperform titer in predictive models of SIV vaccine‐induced protection
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188747
Digitalizing heterologous gene expression in Gram‐negative bacteria with a portable ON/OFF module
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188777
Systematic mapping of protein‐metabolite interactions in central metabolism of Escherichia coli
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199008
Unsupervised identification of disease states from high‐dimensional physiological and histopathological profiles
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188636
A gene regulatory network controls the balance between mesendoderm and ectoderm at pluripotency exit
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199043
Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198947
Reply to “CRISPR screens are feasible in TP53 wild‐type cells”
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199059
Correction to: INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases (Molecular Systems Biology, (2019), 15, 4, (e8250), 10.15252/msb.20188250)
来源期刊:Molecular Systems BiologyDOI:10.15252/MSB.20198981
Disentangling bacterial invasiveness from lethality in an experimental host‐pathogen system
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188707
Sex‐dependent and sex‐independent regulatory systems of size variation in natural populations
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199012
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20198828
Combinatorial prediction of marker panels from single‐cell transcriptomic data
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199005
Tree‐ensemble analysis assesses presence of multifurcations in single cell data
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20188552
Stochastic transcription in the p53‐mediated response to DNA damage is modulated by burst frequency
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.20199068
Enabling next generation systems biology: a conversation with M. Madan Babu
来源期刊:Molecular Systems BiologyDOI:10.15252/msb.199376