Molecular Medicine is an Open Access, international, peer-reviewed, biomedical journal published by the Feinstein Institute for Medical Research (New York).
LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0074-5
Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia
来源期刊:Molecular MedicineDOI:10.1186/s10020-018-0069-7
Further corroboration of distinct functional features in SCN2A variants causing intellectual disability or epileptic phenotypes
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0073-6
CircRNA-9119 suppresses poly I:C induced inflammation in Leydig and Sertoli cells via TLR3 and RIG-I signal pathways
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0094-1
miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0085-2
Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0102-5
Tag-based next generation sequencing: a feasible and reliable assay for EGFR T790M mutation detection in circulating tumor DNA of non small cell lung cancer patients
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0082-5
YAP promotes the malignancy of endometrial cancer cells via regulation of IL-6 and IL-11
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0103-4
A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0090-5
Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
来源期刊:Molecular MedicineDOI:10.1186/s10020-018-0068-8
Post-sepsis syndrome – an evolving entity that afflicts survivors of sepsis
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0132-z
The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0125-y
PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0079-0
Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0084-3
Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0108-z
Validation of impaired Transient Receptor Potential Melastatin 3 ion channel activity in natural killer cells from Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis patients
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0083-4
Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0113-2
Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0107-0
Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0088-z
Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0127-9
Role of 5-HT7 receptors in the immune system in health and disease
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0126-x
Curcumin induced oxidative stress attenuation by N-acetylcysteine co-treatment: a fibroblast and epithelial cell in-vitro study in idiopathic pulmonary fibrosis
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0096-z
Adverse transverse-tubule remodeling in a rat model of heart failure is attenuated with low-dose triiodothyronine treatment
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0120-3
Active repurposing of drug candidates for melanoma based on GWAS, PheWAS and a wide range of omics data
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0098-x
HDAC6 is associated with the formation of aortic dissection in human
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0080-7
IgG Galactosylation status combined with MYOM2-rs2294066 precisely predicts anti-TNF response in ankylosing spondylitis
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0093-2
aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model
来源期刊:Molecular MedicineDOI:10.1186/s10020-018-0067-9
Angiopoietin 1 influences ischemic reperfusion renal injury via modulating endothelium survival and regeneration
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0072-7
Metabolomics analysis elucidates unique influences on purine / pyrimidine metabolism by xanthine oxidoreductase inhibitors in a rat model of renal ischemia-reperfusion injury
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0109-y
Tamoxifen and bone morphogenic protein-7 modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0110-5
Comparison of blood lipid profile/thyroid function markers between unipolar and bipolar depressed patients and in depressed patients with anhedonia or suicidal thoughts
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0119-9
FOXD1 mutations are related to repeated implantation failure, intra-uterine growth restriction and preeclampsia
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0104-3
The cholinergic anti-inflammatory pathway in resistant hypertension treated with renal denervation
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0097-y
Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0123-0
Molecular expression, characterization and mechanism of ALAS2 gain-of-function mutants
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0070-9
PRSS1 mutation: a possible pathomechanism of pancreatic carcinogenesis and pancreatic cancer
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0111-4
CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0089-y
Retinal pigment epithelium degeneration caused by aggregation of PRPF31 and the role of HSP70 family of proteins
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0124-z
Disorders of FZ-CRD; insights towards FZ-CRD folding and therapeutic landscape
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0129-7
HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0131-0
Edaravone reduces oxidative stress and intestinal cell apoptosis after burn through up-regulating miR-320 expression
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0122-1
Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0106-1
Circulating tumor cells: a valuable marker of poor prognosis for advanced nasopharyngeal carcinoma
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0112-3
Club cell protein 16 in sera from trauma patients modulates neutrophil migration and functionality via CXCR1 and CXCR2
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0115-0
Fimasartan reduces neointimal formation and inflammation after carotid arterial injury in apolipoprotein E knockout mice
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0095-0
An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0114-1
Mus musculus deficient for secretory antibodies show delayed growth with an altered urinary metabolome
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0077-2
Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0076-3
Association between admission plasma 2-oxoglutarate levels and short-term outcomes in patients with acute heart failure: a prospective cohort study
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0078-1
Correction to: Plasma Fibrinogen Is a Natural Deterrent to Amyloid β-Induced Platelet Activation and Neuronal Toxicity
来源期刊:Molecular MedicineDOI:10.1186/s10020-019-0100-7