Molecular Diversity is a new publication forum for the rapid publication of refereed papers dedicated to describing the development, application and theory of molecular diversity and combinatorial chemistry in basic and applied research and drug discovery. The journal publishes both short and full papers, perspectives, news and reviews dealing with all aspects of the generation of molecular diversity, application of diversity for screening against alternative targets of all types (biological, biophysical, technological), analysis of results obtained and their application in various scientific disciplines/approaches including:combinatorial chemistry and parallel synthesis;small molecule libraries;microwave synthesis;flow synthesis;fluorous synthesis;diversity oriented synthesis (DOS);nanoreactors;click chemistry;multiplex technologies;fragment- and ligand-based design;structure/function/SAR;computational chemistry and molecular design;chemoinformatics;screening techniques and screening interfaces;analytical and purification methods;robotics, automation and miniaturization;targeted libraries;display libraries;peptides and peptoids;proteins;oligonucleotides;carbohydrates;natural diversity;new methods of library formulation and deconvolution;directed evolution, origin of life and recombination;search techniques, landscapes, random chemistry and more;
分子多样性是一个新的出版论坛，用于快速出版参考论文，这些论文致力于描述分子多样性和组合化学在基础和应用研究以及药物发现中的发展、应用和理论。该杂志发表简短和完整的论文、观点、新闻和评论，涉及分子多样性产生的所有方面，多样性在筛选所有类型（生物、生物物理、技术）的替代目标中的应用，所获得结果的分析及其在各种科学学科/方法中的应用，包括：组合化学和平行合成;小分子文库;微波合成;流动合成;氟合成;面向多样性的综合;纳米反应器;点击化学;多路复用技术;基于片段和配体设计;结构/功能/SAR;计算化学和分子设计;化学信息学;筛选技术和筛选界面;分析和纯化方法;机器人、自动化和小型化;目标文库;显示库;肽和类肽;蛋白质;寡核苷酸;碳水化合物;自然多样性;库公式化和去卷积的新方法;定向进化、生命起源和重组;搜索技术、景观、随机化学等等;
Anchoring of triethanolamine–Cu(II) complex on magnetic carbon nanotube as a promising recyclable catalyst for the synthesis of 5-substituted 1H-tetrazoles from aldehydes
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09951-6
4-Hydroxy-2-quinolones: syntheses, reactions and fused heterocycles
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09952-5
Fe3O4 MNPs as a green catalyst for syntheses of functionalized [1,3]-oxazole and 1H-pyrrolo-[1,3]-oxazole derivatives and evaluation of their antioxidant activity
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09916-9
When global and local molecular descriptors are more than the sum of its parts: Simple, But Not Simpler?
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10002-3
Design and synthesis of new imidazo[1,2-b]pyrazole derivatives, in vitro α-glucosidase inhibition, kinetic and docking studies
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09925-8
Amine-functionalized graphene oxide nanosheets (AFGONs): an efficient bifunctional catalyst for selective formation of 1,4-dihydropyridines, acridinediones and polyhydroquinolines
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09949-0
Combining ligand- and structure-based in silico methods for the identification of natural product-based inhibitors of Akt1
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09924-9
Synthesis and evaluation of chromone derivatives as inhibitors of monoamine oxidase
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09917-8
Comprehensive bioinformatics study reveals targets and molecular mechanism of hesperetin in overcoming breast cancer chemoresistance
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10003-2
Adamantyl pyran-4-one derivatives and their in vitro antiproliferative activity
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09948-1
Lupenone is a good anti-inflammatory compound based on the network pharmacology
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09928-5
Four-component green synthesis of benzochromene derivatives using nano-KF/clinoptilolite as basic catalyst: study of antioxidant activity
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09935-6
Synthesis of highly functionalized organic compounds through Ugi post-transformations started from propiolic acids
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09975-y
Structural characterization of plasmodial aminopeptidase: a combined molecular docking and QSAR-based in silico approaches
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09921-y
Modeling antimalarial and antihuman African trypanosomiasis compounds: a ligand- and structure-based approaches
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10015-y
Design, synthesis, in vivo and in vitro studies of 1,2,3,4-tetrahydro-9H-carbazole derivatives, highly selective and potent butyrylcholinesterase inhibitors
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09943-6
Ciprofloxacin-functionalized magnetic silica nanoparticles: as a reusable catalyst for the synthesis of 1H-chromeno[2,3-d]pyrimidine-5-carboxamides and imidazo[1,2-a]pyridines
来源期刊：Molecular DiversityDOI：10.1007/s11030-018-9907-3
Differential modulation of SIRT6 deacetylase and deacylase activities by lysine-based small molecules
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09971-2
New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09958-z
Synthesis, molecular docking and evaluation of novel sulfonyl hydrazones as anticancer agents and COX-2 inhibitors
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09974-z
Design, synthesis and antifungal activities of novel pyrrole- and pyrazole-substituted coumarin derivatives
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09920-z
New porphyrins: synthesis, characterization, and computational studies
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09955-2
Efficient and environmentally sustainable domino protocol for the synthesis of diversified spiroheterocycles with privileged heterocyclic substructures using bio-organic catalyst in aqueous medium
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09999-4
Synthesis and process optimization of symmetric and unsymmetric barbiturates C5-coupled with 2,1-benzisoxazoles
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09937-4
Regioselective synthesis of pyrimidine-fused tetrahydropyridines and pyridines by microwave-assisted one-pot reaction
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09929-4
Novel fused 1,2,3-triazolo-benzodiazepine derivatives as potent anticonvulsant agents: design, synthesis, in vivo, and in silico evaluations
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09940-9
Ultrasound-assisted synthesis of heterocyclic compounds
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09964-1
Novel amide derivatives of 3-phenylglutaric acid as potent soluble epoxide hydrolase inhibitors
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10023-y
One-pot synthesis of substituted pyrrole–imidazole derivatives with anticancer activity
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09982-z
Synthesis of spirooxindolocarbamates based on Betti reaction: antibacterial, antifungal and antioxidant activities
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10017-w
Semi-rational design of cellobiose dehydrogenase for increased stability in the presence of peroxide
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09965-0
Synthesis and biological evaluation of 2-phenyl-4-aminoquinolines as potential antifungal agents
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10012-1
A four-component reaction: regio- and chemoselective formation of 7-amino-2-(tert-butyl)-5-aryl-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carbonitrile
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09976-x
Lemon juice catalyzed C–C bond formation via C–H activation of methylarene: a sustainable synthesis of chromenopyrimidines
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09980-1
Synthesis and anticholinesterase activity of novel non-hepatotoxic naphthyridine-11-amine derivatives.
来源期刊：Molecular DiversityDOI：10.1007/S11030-018-9897-1
Pd(NHC)(cinnamyl)Cl-catalyzed Suzuki cross-coupling reaction of aryl sulfonates with arylboronic acids.
来源期刊：Molecular diversityDOI：10.1007/s11030-019-10001-4
Application of 2,4-bis(halomethyl)quinoline: synthesis and biological activities of 2,4-bis(benzofuran-2-yl)- and 2,4-bis(aroxymethyl)quinolines
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09938-3
Insights into the current status of privileged N-heterocycles as antileishmanial agents
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09953-4
A quick accelerating microwave-assisted sustainable technique: permutated spiro-casing for imaging experiment
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09934-7
Synthesis, anti-proliferative activity, theoretical and 1H NMR experimental studies of Morita–Baylis–Hillman adducts from isatin derivatives
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09950-7
Nucleophilic phenylation: a remarkable application of alkoxymethyltriphenylphosphonium salts
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09966-z
FeF3-mediated tandem annulation: a highly efficient one-pot synthesis of functionalized N-methyl-3-nitro-4H-pyrimido [2, 1-b] [1, 3] benzothiazole-2-amine derivatives under neat conditions
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09963-2
The monoamine oxidase inhibition properties of C6- and N1-substituted 3-methyl-3,4-dihydroquinazolin-2(1H)-one derivatives
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09960-5
Design, synthesis, in silico and in vitro evaluation of novel diphenyl ether derivatives as potential antitubercular agents
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09990-z
Synthesis and plant growth regulatory activities of 2′,3′-PhABA and iso-2′,3′-PhABA esters
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09931-w
Synthesis and anthelmintic activity of benzopyrano[2,3-c]pyrazol-4(2H)-one derivatives
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10010-3
A novel protocol for catalyst-free synthesis of fused six-member rings to triazole and pyrazole
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09944-5
Facile, efficient and one-pot access to diverse new functionalized aminoalkyl and amidoalkyl naphthol scaffolds via green multicomponent reaction using triethylammonium hydrogen sulfate ([Et3NH][HSO4]) as an acidic ionic liquid under solvent-free conditions
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09945-4
Conformational dynamics of α\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\\alpha $$\\end{document}-conotoxin PnIB in
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-09993-w
Synthesis of new pyrimidine-containing compounds: 5-(2-(alkylamino)-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-6-hydroxypyrimidine-2,4(1H,3H)-dione derivatives
来源期刊：Molecular DiversityDOI：10.1007/s11030-019-10009-w
