Molecular Cancer promotes the exchange of ideas, concepts and findings in any area of cancer and related biomedical science, from a molecular point of view. Molecular Cancer is interested in articles from basic, translational and clinical research, opening new avenues for the understanding, prevention, diagnosis and treatment of cancer. Topics of interest include, but are not limited to: cell and tumor biology, angiogenesis, animal models, metastasis, cancer antigens and the immune response to them, cellular signalling and molecular biology, epidemiology, genetic and molecular profiling of cancer and molecular targets, cancer stem cells, DNA damage and repair, cell cycle, apoptosis, molecular virology and vaccine- and antibody-based cancer therapies.
分子癌症从分子的角度促进癌症和相关生物医学科学任何领域的思想、概念和发现的交流。《分子癌症》对基础、转化和临床研究的文章感兴趣,为理解、预防、诊断和治疗癌症开辟了新的途径。感兴趣的主题包括但不限于:细胞和肿瘤生物学、血管生成、动物模型、转移、癌抗原及其免疫应答、细胞信号传导和分子生物学、流行病学、癌症的遗传和分子特征分析和分子靶标、癌症干细胞、 DNA损伤和修复、细胞周期、细胞凋亡、分子病毒学以及基于疫苗和抗体的癌症治疗。
Targeting PI3K in cancer: mechanisms and advances in clinical trials
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0954-x
Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0991-5
Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0969-3
The role of m6A RNA methylation in human cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1033-z
A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1010-6
Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1091-2
Exosomes in the tumor microenvironment as mediators of cancer therapy resistance
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0975-5
Effects of exosomes on pre-metastatic niche formation in tumors
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0995-1
Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1040-0
METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1065-4
The role of exosomal noncoding RNAs in cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0984-4
Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1031-1
Exosome-orchestrated hypoxic tumor microenvironment
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0982-6
The role of exosomal PD-L1 in tumor progression and immunotherapy
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1074-3
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1022-2
Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m6A reader YTHDF3
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1079-y
MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0988-0
Long noncoding RNA Pvt1 regulates the immunosuppression activity of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0978-2
Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1016-0
Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0960-z
Emerging roles and therapeutic value of exosomes in cancer metastasis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0964-8
Exosomes promote pre-metastatic niche formation in ovarian cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1049-4
Exosomal tRNA-derived small RNA as a promising biomarker for cancer diagnosis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1000-8
Exosomal FMR1-AS1 facilitates maintaining cancer stem-like cell dynamic equilibrium via TLR7/NFκB/c-Myc signaling in female esophageal carcinoma
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0949-7
Targeting interleukin-6 as a strategy to overcome stroma-induced resistance to chemotherapy in gastric cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0972-8
Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1025-z
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0993-3
Circular RNA F-circSR derived from SLC34A2-ROS1 fusion gene promotes cell migration in non-small cell lung cancer
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1028-9
Exo-circRNAs: a new paradigm for anticancer therapy
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0986-2
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0977-3
Role of the dynamic tumor microenvironment in controversies regarding immune checkpoint inhibitors for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1062-7
EGFR-TKI resistance promotes immune escape in lung cancer via increased PD-L1 expression
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1073-4
Functional roles of circular RNAs during epithelial-to-mesenchymal transition
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1071-6
Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0973-7
m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1088-x
Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0971-9
Surgical stress and cancer progression: the twisted tango
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1058-3
ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1077-0
Exosomal miR-21 regulates the TETs/PTENp1/PTEN pathway to promote hepatocellular carcinoma growth
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1075-2
MRE11-RAD50-NBS1 complex alterations and DNA damage response: implications for cancer treatment
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1100-5
Correction to: The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer by sponging anti-tumor miRNAs
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1059-2
Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1070-7
Prostate Cancer-associated SPOP mutations enhance cancer cell survival and docetaxel resistance by upregulating Caprin1-dependent stress granule assembly
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1096-x
Correction to: Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 Kip1 axis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1045-8
The molecular mechanism of LncRNA34a-mediated regulation of bone metastasis in hepatocellular carcinoma
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1044-9
MED12 exerts an emerging role in actin-mediated cytokinesis via LIMK2/cofilin pathway in NSCLC
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1020-4
A critical role of epigenetic inactivation of miR-9 in EVI1high pediatric AML
来源期刊:Molecular CancerDOI:10.1186/s12943-019-0952-z
Correction to: Proteogenomic characterization and comprehensive integrative genomic analysis of human colorectal cancer liver metastasis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1005-3
Retraction Note: Upregulation of the long non-coding RNA AFAP1-AS1 affects the proliferation, invasion and survival of tongue squamous cell carcinoma via the Wnt/β-catenin signaling pathway
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1026-y
Correction to: Circular RNA profiling and its potential for esophageal squamous cell cancer diagnosis and prognosis
来源期刊:Molecular CancerDOI:10.1186/s12943-019-1050-y