It is the primary objective of this publication to encourage the bridging of the gap between clinicians of all relevant specialities and biomedical scientists working in areas from biochemistry and molecular and cell biology to physiology, pharmacology and pathology. A spectrum of topics in medicine will be selected to illustrate not only the molecular insights that derive from the application of basic science, but also the variety of challenging problems that medicine is able to offer the basic scientist.
本出版物的主要目的是鼓励弥合所有相关专业的临床医生与从事生物化学、分子和细胞生物学、生理学、药理学和病理学等领域工作的生物医学科学家之间差距。一系列医学主题将被选择来说明不仅来自基础科学应用的分子见解,而且医学能够为基础科学家提供的各种挑战性问题。
Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.07.001
Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.06.003
Circular RNAs: The star molecules in cancer.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.006
Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential
来源期刊:Molecular Aspects of MedicineDOI:10.1016/j.mam.2019.05.001
Circulating biomarkers for early detection and clinical management of colorectal cancer.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.06.002
Developmental pathways in the pathogenesis of lung fibrosis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.08.004
Cellular and molecular mechanisms of kidney fibrosis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.06.002
Update on genetic predisposition to colorectal cancer and polyposis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.03.001
Lifestyle and dietary environmental factors in colorectal cancer susceptibility.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.06.005
Endoplasmic reticulum stress and development of insulin resistance in adipose, skeletal, liver, and foetoplacental tissue in diabesity.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.11.001
Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.005
Diabesity and mood disorders: Multiple links through the microbiota-gut-brain axis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.11.003
The beneficial effects of brown adipose tissue transplantation.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.06.004
Intestinal fibrosis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.10.003
The importance of long non-coding RNAs in neuropsychiatric disorders.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.07.004
Circulating tumor cell as the functional aspect of liquid biopsy to understand the metastatic cascade in solid cancer.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.07.008
Current concepts of non-coding RNA regulation of immune checkpoints in cancer.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.09.007
Circulating miRNA analysis for cancer diagnostics and therapy.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.002
MiR-200 family and cancer: From a meta-analysis view.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.09.005
The extensive role of miR-155 in malignant and non-malignant diseases.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.09.004
Neurological disorders and mitochondria.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.003
Diabesity-associated oxidative and inflammatory stress signalling in the early human placenta.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.11.002
Involvement of A2B adenosine receptors as anti-inflammatory in gestational diabesity.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.01.001
Glucocorticoids and Brown adipose tissue: Do glucocorticoids really inhibit thermogenesis?
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.07.002
Impaired signalling pathways mediated by extracellular vesicles in diabesity.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.12.001
Diabesity and brain disturbances: A metabolic perspective.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.10.002
Switching on the furnace: regulation of heat production in brown adipose tissue.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.07.005
Epithelial keratins: Biology and implications as diagnostic markers for liquid biopsies.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.09.001
The role of exosomes and MYC in therapy resistance of acute myeloid leukemia: Challenges and opportunities.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.001
Anatomy and physiology of the nutritional system.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.04.001
The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.07.007
Mitochondrially-targeted treatment strategies.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.100836
Mendelian randomisation: A powerful and inexpensive method for identifying and excluding non-genetic risk factors for colorectal cancer
来源期刊:Molecular Aspects of MedicineDOI:10.1016/j.mam.2019.01.002
Diabesity and antidiabetic drugs.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2018.10.004
Colorectal cancer: A paradigmatic model for cancer immunology and immunotherapy.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.05.003
Blood-based bioenergetics: An emerging translational and clinical tool.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.100835
Altered expression of miR-181 affects cell fate and targets drug resistance-related mechanisms.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.007
Switching off the furnace: brown adipose tissue and lactation.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.06.003
Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.03.003
Somatic mutational signatures in polyposis and colorectal cancer.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.05.002
Glioma progression in diabesity.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.02.002
Nanoparticle-aided glycovariant assays to bridge biomarker performance and ctDNA results.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.11.001
Approaches to functionally validate candidate genetic variants involved in colorectal cancer predisposition.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.03.004
Altered foetoplacental vascular endothelial signalling to insulin in diabesity.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.02.003
Emerging isothermal amplification technologies for microRNA biosensing: Applications to liquid biopsies.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.11.002
Mitochondrial bioenergetics and redox dysfunctions in hypercholesterolemia and atherosclerosis.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.100840
Quantification of mitochondrial DNA from peripheral tissues: Limitations in predicting the severity of neurometabolic disorders and proposal of a novel diagnostic test.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.11.004
Molecular evolution of thermogenic uncoupling protein 1 and implications for medical intervention of human disease.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.06.006
Cell-free DNA in blood as a noninvasive insight into the sarcoma genome.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.10.004
Circulating cell-free tumor DNA analysis in pediatric cancers.
来源期刊:Molecular aspects of medicineDOI:10.1016/j.mam.2019.09.003