The Journal of Physiology and Biochemistry publishes original research articles and reviews describing relevant new observations on molecular, biochemical and cellular mechanisms involved in human physiology. All areas of the physiology are covered. Special emphasis is placed on the integration of those levels in the whole-organism. The Journal of Physiology and Biochemistry also welcomes articles on molecular nutrition and metabolism studies, and works related to the genomic or proteomic bases of the physiological functions. Descriptive manuscripts about physiological/biochemical processes or clinical manuscripts will not be considered. The journal will not accept manuscripts testing effects of animal or plant extracts.
《生理学和生物化学杂志》发表原创研究文章和评论，描述与人类生理学有关的分子、生物化学和细胞机制的相关新观察。涵盖了生理学的所有领域。特别强调的是这些水平在整个有机体中的整合。生理学和生物化学杂志也欢迎关于分子营养和代谢研究的文章，以及与生理功能的基因组或蛋白质组学基础相关的作品。不考虑生理/生化过程的描述性手稿或临床手稿。本杂志不接受测试动物或植物提取物效果的稿件。
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00690-8
FGF19 subfamily members: FGF19 and FGF21
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00675-7
Adipose-derived exosomes deliver miR-23a/b to regulate tumor growth in hepatocellular cancer by targeting the VHL/HIF axis
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00692-6
Hepatoprotective effect of gastrodin against alcohol-induced liver injury in mice
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-018-0647-8
THBS4 predicts poor outcomes and promotes proliferation and metastasis in gastric cancer
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00665-9
The role of lamin A/C in mesenchymal stem cell differentiation
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00661-z
MiR-144-3p: a novel tumor suppressor targeting MAPK6 in cervical cancer
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00681-9
Hesperetin is a potent bioactivator that activates SIRT1-AMPK signaling pathway in HepG2 cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00678-4
Diabetes abolish cardioprotective effects of remote ischemic conditioning: evidences and possible mechanisms
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00664-w
Gastrodin ameliorates microvascular reperfusion injury–induced pyroptosis by regulating the NLRP3/caspase-1 pathway
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00702-7
HULC functions as an oncogene in ovarian carcinoma cells by negatively modulating miR-125a-3p
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00669-5
A large proportion of mediastinal and perirenal visceral fat of Siberian adult people is formed by UCP1 immunoreactive multilocular and paucilocular adipocytes
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00721-4
Melatonin induces reactive oxygen species generation and changes in glutathione levels and reduces viability in human pancreatic stellate cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00671-x
MicroRNAs as the actors in the atherosclerosis scenario
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00710-7
Long non-coding RNA Mirt2 relieves lipopolysaccharide-induced injury in PC12 cells by suppressing miR-429
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00691-7
Omega-3 fatty acids as regulators of brown/beige adipose tissue: from mechanisms to therapeutic potential
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00720-5
Triptolide inhibits angiogenesis in microvascular endothelial cells through regulation of miR-92a
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00707-2
Dysregulated expression of ACTN4 contributes to endothelial cell injury via the activation of the p38-MAPK/p53 apoptosis pathway in preeclampsia
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00700-9
The role of autophagy in brown and beige adipose tissue plasticity
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00708-1
Alterations of HDL particle phospholipid composition and role of inflammation in rheumatoid arthritis
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00694-4
Baicalin relieves inflammation stimulated by lipopolysaccharide via upregulating TUG1 in liver cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00698-0
LPS-squalene interaction on d-galactose intestinal absorption
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00682-8
Modifications of short-term intrinsic pacemaker variability in diet-induced metabolic syndrome: a study on isolated rabbit heart
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00667-7
Obesity and aging affects skeletal muscle renin–angiotensin system and myosin heavy chain proportions in pre-diabetic Zucker rats
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00689-1
Impact of different methods of induction of cellular hypoxia: focus on protein homeostasis signaling pathways and morphology of C2C12 skeletal muscle cells differentiated into myotubes
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00687-3
Involvement of miR-30b in kynurenine-mediated lysyl oxidase expression
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00686-4
The regulation of inflammation-related genes after palmitic acid and DHA treatments is not mediated by DNA methylation
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00685-5
L-type Ca2+ channels’ involvement in IFN-γ-induced signaling in rat ventricular cardiomyocytes
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00662-y
miR-1 induces endothelial dysfunction in rat pulmonary arteries
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00696-2
Effects of resveratrol and its analogue pterostilbene, on NOV/CCN3 adipokine in adipose tissue from rats fed a high-fat high-sucrose diet
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00680-w
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00711-6
The relevance of AMP-activated protein kinase in insulin-secreting β cells: a potential target for improving β cell function?
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00706-3
Transcriptome analysis reveals the molecular mechanisms of combined gamma-tocotrienol and hydroxychavicol in preventing the proliferation of 1321N1, SW1783, and LN18 glioma cancer cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00699-z
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00674-8
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00703-6
About the controversies of the cardioprotective effect of n-3 polyunsaturated fatty acids (PUFAs) between animal studies and clinical meta-analyses: a review with several strategies to enhance the beneficial effects of n-3 PUFAs
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00670-y
Glutathione-dependent enzyme activities of peripheral blood mononuclear cells decrease during the winter season compared with the summer in normal-weight and severely obese adolescents
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00693-5
Plasma lactate and leukocyte mitochondrial DNA copy number as biomarkers of insulin sensitivity in non-diabetic women
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00672-w
Expression of lipogenic markers is decreased in subcutaneous adipose tissue and adipocytes of older women and is negatively linked to GDF15 expression
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00676-6
Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca2+ alterations in endothelial cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00715-2
HYPOTHesizing about central comBAT against obesity
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00719-y
Netrin-1 promotes the collective cell migration of liver cancer cells in a 3D cell culture model
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00701-8
Characterization of gut microbiota composition in HIV-infected patients with metabolic syndrome
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00673-9
Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury by inhibiting STIM1-mediated intracellular calcium accumulation
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00704-5
Protective effects of atorvastatin on high glucose-induced oxidative stress and mitochondrial apoptotic signaling pathways in cultured chondrocytes
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00666-8
c-Jun promotes the survival of H9c2 cells under hypoxia via PTEN/Akt signaling pathway
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00695-3
One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00705-4
Effects of the amino acid derivatives, β-hydroxy-β-methylbutyrate, taurine, and N-methyltyramine, on triacylglycerol breakdown in fat cells
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00677-5
Na+/H+ exchanger isoform 1 activity in AQP2-expressing cells can be either proliferative or anti-proliferative depending on extracellular pH
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00713-4
Sex-specific differences in rat soleus muscle signaling pathway responses to a bout of horizontal and downhill running
来源期刊：Journal of Physiology and BiochemistryDOI：10.1007/s13105-019-00712-5
