The Journal of Pathology aims to serve as a translational bridge between basic biomedical science and clinical medicine with particular emphasis on, but not restricted to, tissue based studies. The main interests of the Journal lie in publishing studies that further our understanding the pathophysiological and pathogenetic mechanisms of human disease. The Journal welcomes investigative studies on human tissues, in vitro and in vivo experimental studies, and investigations based on animal models with a clear relevance to human disease, including transgenic systems. In general, hypothesis driven studies that appropriately employ multiple investigative techniques are preferred over those that rely on a single methodology. As well as original research papers, the Journal seeks to provide rapid publication in a variety of other formats, including editorials, review articles, commentaries and perspectives and other features, both contributed and solicited. Purely descriptive papers on diagnostic pathology (including case reports and prognostic papers without mechanistic and experimental insights) are not considered central to the Journal’s purpose. Correspondence relating to papers published in the Journal will be considered, but only if of general interest. Such correspondance may be published in online versions only, at the Editor's discretion. In determining content, the primary considerations are excellence, relevance and novelty. As the journal of The Pathological Society, it seeks to reflect the broad scientific interests of the Society’s membership but its ethos, authorship, content and purpose are those expected of a leading publication in the international scientific literature.
病理学杂志旨在作为基础生物医学科学和临床医学之间的转化桥梁,特别强调但不限于基于组织的研究。该杂志的主要兴趣在于发表研究,进一步了解人类疾病的病理生理学和发病机制。该杂志欢迎对人体组织的调查研究、体外和体内实验研究,以及基于与人类疾病明确相关的动物模型的研究,包括转基因系统。一般而言,与依赖于单一方法的研究相比,首选适当采用多种研究技术的假设驱动研究。除了原创研究论文外,《日刊》还力求以各种其他形式迅速发表,包括社论、评论文章、评论和观点以及其他特写,包括投稿和征求的。关于诊断病理学的纯粹描述性论文(包括病例报告和预后论文,没有机制和实验见解)不被认为是杂志宗旨的核心。与《日刊》上发表的论文有关的信件将被考虑,但只有在普遍感兴趣的情况下。编辑可自行决定仅以在线版本发布此类通信。在确定内容时,主要考虑的是卓越性、相关性和新奇性。作为病理学会的期刊,它力求反映学会成员的广泛科学兴趣,但其精神、作者、内容和目的是国际科学文献中领先出版物所期望的。
Autophagy, cancer stem cells and drug resistance
来源期刊:The Journal of PathologyDOI:10.1002/path.5222
Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential
来源期刊:The Journal of PathologyDOI:10.1002/path.5221
Recent advances in understanding the roles of matrix metalloproteinases in tumour invasion and metastasis
来源期刊:The Journal of PathologyDOI:10.1002/path.5225
Artificial intelligence in digital pathology: a roadmap to routine use in clinical practice
来源期刊:The Journal of PathologyDOI:10.1002/path.5310
Long non‐coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1‐AS1
来源期刊:The Journal of PathologyDOI:10.1002/path.5195
Interpretation of somatic POLE mutations in endometrial carcinoma
来源期刊:The Journal of PathologyDOI:10.1002/path.5372
Activating mutations in the MAP‐kinase pathway define non‐ossifying fibroma of bone
来源期刊:The Journal of PathologyDOI:10.1002/path.5216
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine
来源期刊:The Journal of PathologyDOI:10.1002/path.5364
Intratumour heterogeneity of p53 expression; causes and consequences
来源期刊:The Journal of PathologyDOI:10.1002/path.5328
Molecular alterations associated with metastases of solid pseudopapillary neoplasms of the pancreas
来源期刊:The Journal of PathologyDOI:10.1002/path.5180
Cold atmospheric plasma modulates endothelial nitric oxide synthase signalling and enhances burn wound neovascularisation
来源期刊:The Journal of PathologyDOI:10.1002/path.5323
Keratin 17 in disease pathogenesis: from cancer to dermatoses
来源期刊:The Journal of PathologyDOI:10.1002/path.5178
Interferon‐γ directly induces gastric epithelial cell death and is required for progression to metaplasia
来源期刊:The Journal of PathologyDOI:10.1002/path.5214
NOX2 in autoimmunity, tumor growth and metastasis†
来源期刊:The Journal of PathologyDOI:10.1002/path.5175
TET1 reprograms the epithelial ovarian cancer epigenome and reveals casein kinase 2α as a therapeutic target
来源期刊:The Journal of PathologyDOI:10.1002/path.5266
Tspan8 is expressed in breast cancer and regulates E‐cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles
来源期刊:The Journal of PathologyDOI:10.1002/path.5281
Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
来源期刊:The Journal of PathologyDOI:10.1002/path.5200
Genomic landscape of lymphoepithelioma‐like hepatocellular carcinoma
来源期刊:The Journal of PathologyDOI:10.1002/path.5313
Initial and crucial genetic events in intestinal‐type gastric intramucosal neoplasia
来源期刊:The Journal of PathologyDOI:10.1002/path.5208
Genomic characterisation of breast fibroepithelial lesions in an international cohort
来源期刊:The Journal of PathologyDOI:10.1002/path.5333
Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension
来源期刊:The Journal of PathologyDOI:10.1002/path.5322
Bmi1 marks gastric stem cells located in the isthmus in mice
来源期刊:The Journal of PathologyDOI:10.1002/path.5244
Molecular mechanisms in chaperonopathies: clues to understanding the histopathological abnormalities and developing novel therapies
来源期刊:The Journal of PathologyDOI:10.1002/path.5349
Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis
来源期刊:The Journal of PathologyDOI:10.1002/path.5215
Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury
来源期刊:The Journal of PathologyDOI:10.1002/path.5234
Inflammatory macrophages switch to CCL17‐expressing phenotype and promote peritoneal fibrosis
来源期刊:The Journal of PathologyDOI:10.1002/path.5350
Mitochondrial dysfunction and role of harakiri in the pathogenesis of myositis
来源期刊:The Journal of PathologyDOI:10.1002/path.5309
Fusobacterium nucleatum facilitates ulcerative colitis through activating IL‐17F signaling to NF‐κB via the upregulation of CARD3 expression
来源期刊:The Journal of PathologyDOI:10.1002/path.5358
Doxorubicin‐induced cardiotoxicity involves IFNγ‐mediated metabolic reprogramming in cardiomyocytes
来源期刊:The Journal of PathologyDOI:10.1002/path.5192
The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis
来源期刊:The Journal of PathologyDOI:10.1002/path.5171
Morpholino‐induced exon skipping stimulates cell‐mediated and humoral responses to dystrophin in mdx mice
来源期刊:The Journal of PathologyDOI:10.1002/path.5263
Molecular comparison of interval and screen‐detected breast cancers
来源期刊:The Journal of PathologyDOI:10.1002/path.5251
ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors
来源期刊:The Journal of PathologyDOI:10.1002/path.5356
CD70 expression correlates with a worse prognosis in malignant pleural mesothelioma patients via immune evasion and enhanced invasiveness
来源期刊:The Journal of PathologyDOI:10.1002/path.5361
Increased expression of neurotensin in high grade serous ovarian carcinoma with evidence of serous tubal intraepithelial carcinoma
来源期刊:The Journal of PathologyDOI:10.1002/path.5264
Protective role of c‐Jun N‐terminal kinase‐2 (JNK2) in ibuprofen‐induced acute liver injury
来源期刊:The Journal of PathologyDOI:10.1002/path.5174
Gamma‐secretase complex‐dependent intramembrane proteolysis of CD147 regulates the Notch1 signaling pathway in hepatocellular carcinoma
来源期刊:The Journal of PathologyDOI:10.1002/path.5316
Overactivity or blockade of transforming growth factor‐β each generate a specific ureter malformation
来源期刊:The Journal of PathologyDOI:10.1002/path.5335
Mineralocorticoid receptor negatively regulates angiogenesis through repression of STAT3 activity in endothelial cells
来源期刊:The Journal of PathologyDOI:10.1002/path.5269
Bile ductular reactions in the liver: similarities are only skin deep
来源期刊:The Journal of PathologyDOI:10.1002/path.5265
YWHAZ amplification/overexpression defines aggressive bladder cancer and contributes to chemo‐/radio‐resistance by suppressing caspase‐mediated apoptosis
来源期刊:The Journal of PathologyDOI:10.1002/path.5274
More expression, less function: cleaved dynamin in glomerular kidney disease
来源期刊:The Journal of PathologyDOI:10.1002/path.5217
Making sense of giant cell lesions of the jaws (GCLJ): lessons learned from next‐generation sequencing
来源期刊:The Journal of PathologyDOI:10.1002/path.5365
Hippo pathway effectors YAP1/TAZ induce an EWS–FLI1‐opposing gene signature and associate with disease progression in Ewing sarcoma
来源期刊:The Journal of PathologyDOI:10.1002/path.5379
Tumor and endothelial cells collaborate via transcellular receptor complexes
来源期刊:The Journal of PathologyDOI:10.1002/path.5185
Germline mutation and aberrant transcripts of WWOX in a syndrome with multiple primary tumors
来源期刊:The Journal of PathologyDOI:10.1002/path.5288
Autoimmune response and its long‐term consequences after exon‐skipping therapy in a Duchenne muscular dystrophy mouse model
来源期刊:The Journal of PathologyDOI:10.1002/path.5327
Issue Information
来源期刊:The Journal of PathologyDOI:10.1002/path.5112
Development of a predictive model for stromal content in prostate cancer samples to improve signature performance
来源期刊:The Journal of PathologyDOI:10.1002/path.5315
A new mouse model for the neurodevelopmental ciliopathy Joubert syndrome
来源期刊:The Journal of PathologyDOI:10.1002/path.5291