AAPS PharmSciTech is a peer-reviewed, online-only journal committed to serving those pharmaceutical scientists and engineers interested in the research, development, and evaluation of pharmaceutical dosage forms and delivery systems, including drugs derived from biotechnology and the manufacturing science pertaining to the commercialization of such dosage forms. Because of its electronic nature, AAPS PharmSciTech aspires to utilize evolving electronic technology to enable faster and diverse mechanisms of information delivery to its readership. Submission of uninvited expert reviews and research articles are welcomed.
AAPS PharmSciTech是一本同行评审的在线期刊，致力于为那些对药物剂型和给药系统的研究、开发和评价感兴趣的药学科学家和工程师提供服务，包括生物技术衍生药物和与此类剂型商业化相关的制造科学。由于其电子性质， AAPS制药科技渴望利用不断发展的电子技术，使更快和多样化的信息传递机制，其读者。欢迎提交未经邀请的专家评论和研究文章。
Abuse Deterrent Immediate Release Egg-Shaped Tablet (Egglets) Using 3D Printing Technology: Quality by Design to Optimize Drug Release and Extraction
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1298-y
Development, Optimization, and In Vitro/In Vivo Characterization of Enhanced Lipid Nanoparticles for Ocular Delivery of Ofloxacin: the Influence of Pegylation and Chitosan Coating
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1371-6
Fabrication Strategies of Scaffolds for Delivering Active Ingredients for Tissue Engineering
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1470-4
Folate-Functionalized Thiomeric Nanoparticles for Enhanced Docetaxel Cytotoxicity and Improved Oral Bioavailability
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1297-z
Preformulation and Evaluation of Tofacitinib as a Therapeutic Treatment for Asthma
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1377-0
Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1421-0
3D-Printed Wearable Personalized Orthodontic Retainers for Sustained Release of Clonidine Hydrochloride
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1460-6
Drug–Lipid Conjugates for Enhanced Oral Drug Delivery
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-018-1272-0
Temozolomide Conjugated Carbon Quantum Dots Embedded in Core/Shell Nanofibers Prepared by Coaxial Electrospinning as an Implantable Delivery System for Cell Imaging and Sustained Drug Release
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1466-0
Improved Oral Absorption of Poorly Soluble Curcumin via the Concomitant Use of Borneol
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1364-5
Crystal Transformation of β-CD-MOF Facilitates Loading of Dimercaptosuccinic Acid
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1422-z
Stable Immune Response Induced by Intradermal DNA Vaccination by a Novel Needleless Pyro-Drive Jet Injector
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1564-z
Efficacy of Ciprofloxacin and Its Copper Complex against Pseudomonas aeruginosa Biofilms
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1417-9
Preparation, Characterization and Antioxidant Evaluation of Poorly Soluble Polyphenol-Loaded Nanoparticles for Cataract Treatment
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1379-y
Investigation of Controlled Release Molecular Mechanism of Oil Phase in Spilanthol Emulsion: Development and In Vitro, In Vivo Characterization
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1454-4
Enhanced Oral Absorption of Amisulpride Via a Nanostructured Lipid Carrier-Based Capsules: Development, Optimization Applying the Desirability Function Approach and In Vivo Pharmacokinetic Study
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-018-1283-x
Assessment of Biopharmaceutical Performance of Supersaturating Formulations of Carbamazepine in Rats Using Physiologically Based Pharmacokinetic Modeling
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1386-z
Preparation of Peppermint Oil-Based Nanodevices Loaded with Paclitaxel: Cytotoxic and Apoptosis Studies in HeLa Cells
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1399-7
Formulation and Characterization of Nanosized Ethosomal Formulations of Antigout Model Drug (Febuxostat) Prepared by Cold Method: In Vitro/Ex Vivo and In Vivo Assessment
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1556-z
Quality by Design Enabled Development of Oral Self-Nanoemulsifying Drug Delivery System of a Novel Calcimimetic Cinacalcet HCl Using a Porous Carrier: In Vitro and In Vivo Characterisation
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1411-2
Quality by Design Approach for the Development of Self-Emulsifying Systems for Oral Delivery of Febuxostat: Pharmacokinetic and Pharmacodynamic Evaluation
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1476-y
Dissolvable Microneedle-Mediated Transcutaneous Delivery of Tetanus Toxoid Elicits Effective Immune Response
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1471-3
Impact of Process Parameters on Particle Size Involved in Media Milling Technique Used for Preparing Clotrimazole Nanocrystals for the Management of Cutaneous Candidiasis
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1368-1
Formulation of Direct Compression Zidovudine Tablets to Correlate the SeDeM Diagram Expert System and the Rotary Press Simulator Styl’ONE Results
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1542-5
Ultrasound-Assisted Facile Synthesis of Nanostructured Hybrid Vesicle for the Nasal Delivery of Indomethacin: Response Surface Optimization, Microstructure, and Stability
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-018-1247-1
A Drug Release Model Constructed by Factorial Design to Investigate the Interaction Between Host Mesoporous Silica Carriers and Drug Molecules
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1340-0
Small-Scale Tools to Assess the Impact of Interfacial and Shear Stress on Biologic Drug Products
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1378-z
Thermal Extrusion 3D Printing for the Fabrication of Puerarin Immediate-Release Tablets
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1538-1
Eco-Friendly Tadalafil Surfactant-Free Dry Emulsion Tablets (SFDETs) Stabilized by In Situ Self-Assembled Aggregates of Natural Oil and Native Cyclodextrins
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1450-8
Effect of Roughness on the Dispersion of Dry Powders for Inhalation: a Dynamic Visualization Perspective
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1482-0
Determination of Passive Dry Powder Inhaler Aerodynamic Particle Size Distribution by Multi-Stage Cascade Impactor: International Pharmaceutical Aerosol Consortium on Regulation & Science (IPAC-RS) Recommendations to Support Both Product Quality Control and Clinical Programs
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1416-x
Implication of Coformer Structural Diversity on Cocrystallization Outcomes of Telmisartan with Improved Biopharmaceutical Performance
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1559-9
Potential Active Targeting of Gatifloxacin to Macrophages by Means of Surface-Modified PLGA Microparticles Destined to Treat Tuberculosis
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1552-3
Combination of Colloidal Silicon Dioxide with Spray-Dried Solid Dispersion to Facilitate Discharge from an Agitated Dryer
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1392-1
Development, Optimization, and Evaluation In Vitro/In Vivo of Oral Liquid System for Synchronized Sustained Release of Levodopa/Benserazide
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1511-z
Prediction of Dissolution of Sustained Release Coated Ciprofloxacin Beads Using Near-infrared Spectroscopy and Process Parameters: a Data Fusion Approach
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1401-4
In vitro–In vivo Relationship and Bioequivalence Prediction for Modified-Release Capsules Based on a PBPK Absorption Model
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1566-x
Sustained Release Ziprasidone Microparticles Prepared by Spray Drying with Soluplus® and Ethyl Cellulose to Eliminate Food Effect and Enhance Bioavailability
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1592-8
Simultaneous Evaluation of Dissolution and Permeation of Oral Drug Solid Formulations for Predicting Absorption Rate–Limiting Factors and In Vitro–In Vivo Correlations: Case Study Using a Poorly Soluble Weakly Basic Drug
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1544-3
Approaches for Delivery of Drugs Topically
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1582-x
Preparation and Evaluation of mPEG-PLGA Block Copolymer Micelles Loaded with a Sarsasapogenin Derivative
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1491-z
A Novel Micron-Size Particulate Formulation of Felodipine with Improved Release and Enhanced Oral Bioavailability Fabricated by Coaxial Electrospray
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1495-8
E-Selectin-Binding Peptide–Modified Bovine Serum Albumin Nanoparticles for the Treatment of Acute Lung Injury
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1403-2
Investigating the Effect of APAP Crystals on Tablet Behavior Manufactured by Direct Compression
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1369-0
Risedronate-Loaded Macroporous Gel Foam Enriched with Nanohydroxyapatite: Preparation, Characterization, and Osteogenic Activity Evaluation Using Saos-2 Cells
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1292-4
Enhanced the Bioavailability of Sterile 20(S)-Protopanaxadiol Nanocrystalline Suspension Coated by Bovine Serum Albumin for Intramuscular Injection: In Vitro and In Vivo Evaluation
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1498-5
Mapping Fusogenicity of Ciprofloxacin-Loaded Liposomes with Bacterial Cells
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1381-4
Development of High-Strength Extended-Release Multiparticulate System by Crystallo-co-agglomeration Technique with Integration of Central Composite Design
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1390-3
Liver Targeting Albumin-Coated Silybin-Phospholipid Particles Prepared by Nab™ Technology for Improving Treatment Effect of Acute Liver Damage in Intravenous Administration
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1504-y
Development of Methotrexate and Minocycline-Loaded Nanoparticles for the Effective Treatment of Rheumatoid Arthritis
来源期刊：AAPS PharmSciTechDOI：10.1208/s12249-019-1581-y
