General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization.The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.
普通生理学是通过分析研究生物学机制的研究，它解释了组织各级生物功能的分子和细胞机制。普通生理学杂志（JGP）的使命是出版最高质量的分子和细胞生理学的机制和定量，提供一流的作者经验，并培养未来的独立研究人员。主要强调细胞和分子水平上的生理问题。
Evolution of our understanding of cell volume regulation by the pump-leak mechanism
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812274
Sarcomere length–dependent effects on Ca2+-troponin regulation in myocardium expressing compliant titin
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812218
Inotropic interventions do not change the resting state of myosin motors during cardiac diastole
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812196
Voltage-clamp recordings of light responses from wild-type and mutant mouse cone photoreceptors
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912419
Serotonin transport in the 21st century
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812066
Noncompetitive antagonists induce cooperative AMPA receptor channel gating
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812209
Unraveling the mechanisms of calcium-dependent secretion
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812298
Spontaneous transitions of actin-bound tropomyosin toward blocked and closed states
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812188
Antidepressants are modifiers of lipid bilayer properties
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812263
Comparison of ion transport determinants between a TMEM16 chloride channel and phospholipid scramblase
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812270
A channel profile report of the unusual K+ channel KtrB
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912384
Glucose stimulates somatostatin secretion in pancreatic δ-cells by cAMP-dependent intracellular Ca2+ release
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912351
Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812293
Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201711884
Methodological improvements for fluorescence recordings in Xenopus laevis oocytes
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812189
Mitoflash biogenesis and its role in the autoregulation of mitochondrial proton electrochemical potential
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812176
Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812264
Concatenated γ-aminobutyric acid type A receptors revisited: Finding order in chaos
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812133
Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812210
Developmental increase in β-MHC enhances sarcomere length–dependent activation in the myocardium
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812183
Investigation into the mechanism of thin filament regulation by transient kinetics and equilibrium binding: Is there a conflict?
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812198
3-Chlorodiphenylamine activates cardiac troponin by a mechanism distinct from bepridil or TFP
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812131
Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812234
Comparing pathways for long-term heart rate modulation by the funny current
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912409
Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812214
cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812019
A mutation in CaV2.1 linked to a severe neurodevelopmental disorder impairs channel gating
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812237
Prying open a glutamate receptor gate
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812312
How dendritic spines shape calcium dynamics
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912432
Determining the dynamics of cancer cell secretion
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912518
Interpretation of spectroscopic data using molecular simulations for the secondary active transporter BetP
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812111
N- and C-terminal interactions in KCNH channels: The spotlight on the intrinsic ligand
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812313
Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812108
A four-electrode method to study dynamics of ion activity and transport in skeletal muscle fibers
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912398
Modeling GIRK channel conductance
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912479
Tracking nitroxyl-derived posttranslational modifications of phospholamban in cardiac myocytes
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912342
Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812221
Excluding scientist survivors from the NASEM Action Collaborative is a step backward in changing culture to prevent sexual harassment
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912393
Interrogating the conformational dynamics of BetP transport
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201812315
Isolating a reverse-mode ATP synthase–dependent mechanism of mitoflash activation
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912358
Measurement of intracellular ion activity in skeletal muscle fibers: Four microelectrodes or no deal
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912425
CFTR gets together
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912385
With PIPs, you get ZIPs and blips
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912402
Small calcium leaks, big muscle adaptations
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912356
Rhomboids make do with a weak hydrogen bond
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912334
The mechanism of photon-like dark noise in rod photoreceptors
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912376
Elastic domains of giant proteins in striated muscle: Modeling compliance with rulers
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912345
Membrane physiologists of all kinds meet at Woods Hole
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912340
Paul F. Cranefield Award to Anne E. Carlson
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912433
Onward and upward
来源期刊：The Journal of General PhysiologyDOI：10.1085/jgp.201912321
