JACC: Basic to Translational Science, is one of a family of specialist journals launched by the renowned Journal of the American College of Cardiology (JACC). An open access journal, it serves as forum for advancing the field Translational Cardiovascular Medicine, and as a platform for accelerating the translation of novel scientific discoveries into new therapies that improve clinical outcomes for patients affected with or at risk for Cardiovascular Disease. Thematic areas of interest include pre-clinical research; clinical trials; personalized medicine; novel drugs, devices, and biologics; proteomics, genomics and metabolomics; and early phase clinical trial methodology.
Jacc-基础到转化科学(Jacc-basic To Translational Science)是一本由ELSEVIER SCIENCE INC出版的一本CARDIAC & CARDIOVASCULAR SYSTEMS学术刊物，主要报道CARDIAC & CARDIOVASCULAR SYSTEMS相关领域研究成果与实践。本刊已入选来源期刊，出版周期12 issues/year。2021-2022年最新版WOS分区等级：Q1，2023年发布的影响因子为8.4，CiteScore指数14.2，SJR指数2.69。本刊为开放获取期刊。 JACC：从基础到转化科学，是著名的《美国心脏病学会杂志》（JACC）推出的一系列专业期刊之一。作为一本开放获取期刊，它充当了推进转化心血管医学领域的论坛，并充当了加速将新科学发现转化为新疗法的平台，这些新疗法可改善患有或有患心血管疾病风险的患者的临床结果。感兴趣的主题领域包括临床前研究；临床试验；个性化医疗；新型药物、设备和生物制剂；蛋白质组学、基因组学和代谢组学；以及早期临床试验方法。
First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.07.012
Empagliflozin Improves Diastolic Function in a Nondiabetic Rodent Model of Heart Failure With Preserved Ejection Fraction
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.010
Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.10.008
Epigenetics in Cardiac Hypertrophy and Heart Failure
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.05.011
Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.03.004
Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.10.003
Cardiac Nuclear High-Mobility Group Box 1 Ameliorates Pathological Cardiac Hypertrophy by Inhibiting DNA Damage Response
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.011
CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.07.004
Perioperatively Inhaled Hydrogen Gas Diminishes Neurologic Injury Following Experimental Circulatory Arrest in Swine
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.006
Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid–CB1-R Signaling
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.05.007
Characterization of a Unique Form of Arrhythmic Cardiomyopathy Caused by Recessive Mutation in LEMD2
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.12.001
A Molecularly Detailed NaV1.5 Model Reveals a New Class I Antiarrhythmic Target
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.06.002
Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.009
Celecoxib Is Associated With Dystrophic Calcification and Aortic Valve Stenosis
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.12.003
Angiopoietin-Like 3
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.05.008
Phase II Trials in Drug Development and Adaptive Trial Design.
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/J.JACBTS.2019.02.005
Cardiac Myosin Binding Protein-C Phosphorylation Mitigates Age-Related Cardiac Dysfunction
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.06.003
Chest Compressions During Sustained Inflation During Cardiopulmonary Resuscitation in Newborn Infants Translating Evidence From Animal Studies to the Bedside
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.12.004
Bioactive Materials Facilitating Targeted Local Modulation of Inflammation
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.10.004
Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.06.006
Seipin Knockout Mice Develop Heart Failure With Preserved Ejection Fraction
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.07.008
Phosphorylation of Hsp20 Promotes Fibrotic Remodeling and Heart Failure
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.007
Overcoming Barriers to Development of Novel Therapies for Cardiovascular Disease
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.011
Quantification of DNA Damage in Heart Tissue as a Novel Prediction Tool for Therapeutic Prognosis of Patients With Dilated Cardiomyopathy
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.05.010
The Growing Case for Use of SGLT2i in Heart Failure
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.003
Limitations of Animal Studies for Predicting Toxicity in Clinical Trials
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.10.008
Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.012
Modulation of Glucagon Signaling
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.03.006
Dipeptidyl Peptidase-4 Inhibition Prevents Vascular Calcification by Potentiating the Insulin-Like Growth Factor-1 Signaling Pathway
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.11.002
Adaptive Reductions in Left Ventricular Diastolic Compliance Protect the Heart From Stretch-Induced Stunning
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.04.002
Glucagon-Like Peptide-1–Mediated Cardioprotection Does Not Reduce Right Ventricular Stunning and Cumulative Ischemic Dysfunction After Coronary Balloon Occlusion
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2018.12.002
Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.06.001
The Hippo in the Clinic
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.08.004
Putting the Heat on Cardiac Fibrosis
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.03.007
Cardiac Versus Renal Response to Volume Expansion in Preclinical Systolic Dysfunction With PDEV Inhibition and BNP
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.08.008
DNA Damage Prediction Tool in Dilated Cardiomyopathy
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.08.005
The New Promise of Mitochondrial Transplantation for Myocardial Recovery∗
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.11.009
Empagliflozin and HFrEF
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.10.005
Connecting the Dots for Connective Tissue Growth Factor Roles in Cardiac Wound Healing After Myocardial Infarction∗
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.004
Empagliflozin and Protecting Microvascular Support of Heart Mechanics
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.08.003
It’s a SMAD, SMAD World
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.006
Nuclear Hmgb1
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.03.008
JACC: Basic to Translational Science
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.07.003
Paradoxical Cardiorenal Responses Following Acute Vasodilator/Natriuretic Treatment in Presystolic Heart Failure
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.11.002
Therapeutic Treatment Approaches Post–Myocardial Infarction
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.11.008
The Bslc2–/– Mouse
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.11.004
A Novel Mechanism to Explain Statin-Associated Skeletal Muscle Symptoms∗
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.07.001
JACC: Basic to Translational Science 2018 Young Author Award Winner
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.01.007
Scott Gottlieb’s Resignation as FDA Commissioner Is a Loss for Translational Medicine
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.03.001
Interleukin 5 Contributes to Human Atherosclerosis Development But not to Thrombotic Complications∗
来源期刊：JACC: Basic to Translational ScienceDOI：10.1016/j.jacbts.2019.11.005
