The Journal of Controlled Release (JCR) publishes high-quality research articles in the broad field of delivery science and technology. This includes drug delivery systems and all aspects of formulations, such as physicochemical and biological properties of drugs, design and characterization of dosage forms, release mechanisms, in vivo testing, and formulation research and development in the disciplines of pharmaceutical, diagnostic, agricultural, environmental, cosmetic, and food industries. Manuscripts that advance fundamental understanding of principles and/or demonstrate advantages of novel technologies in safety and efficacy over current clinical standards will be given priority. Each issue has the cover story highlighting the significance of a selected article published in the issue. At the end of each quarter, the JCR editors select "The Editors' Choice" from the published research articles.
Journal of Controlled Release (JCR)在广泛的递送科学和技术领域发表高质量的研究文章。这包括药物递送系统和制剂的所有方面，例如药物的物理化学和生物学特性、剂型的设计和表征、释放机制、体内测试以及制药、诊断、农业、环境学科中的制剂研发、化妆品和食品行业。优先考虑推进对原理的基本理解和/或展示新技术在安全性和有效性方面优于当前临床标准的优势的手稿。每期都有封面故事，突出了该期发表的选定文章的重要性。在每个季度末，JCR编辑会从已发表的研究文章中选出“编辑之选”。
Drying technology strategies for colon‐targeted oral delivery of biopharmaceuticals
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.023
Understanding structure‐activity relationships of pH‐sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.001
Modulating the antibody density changes the uptake and transport at the blood‐brain barrier of both transferrin receptor‐targeted gold nanoparticles and liposomal cargo
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.005
Recent advances in topical delivery of flavonoids: A review
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.029
MicroRNA delivery through nanoparticles
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.10.007
New insights into designing hybrid nanoparticles for lung cancer: Diagnosis and treatment
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.009
Pulmonary delivery by exploiting doxorubicin and cisplatin co‐loaded nanoparticles for metastatic lung cancer therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.013
Two‐dimensional cancer theranostic nanomaterials: Synthesis, surface functionalization and applications in photothermal therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.015
Controlled release strategy designed for intravitreal protein delivery to the retina
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.11.012
cRGD‐decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.03.005
Glycosaminoglycan-based biomaterials for growth factor and cytokine delivery: Making the right choices
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.10.018
Aligned microchannel polymer‐nanotube composites for peripheral nerve regeneration: Small molecule drug delivery
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.013
Immunomodulatory properties of MSC‐derived exosomes armed with high affinity aptamer toward mylein as a platform for reducing multiple sclerosis clinical score
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.032
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.048
Alginate/chitosan microparticles for gastric passage and intestinal release of therapeutic protein nanoparticles
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.017
Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug‐light intervals
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.030
Ultrasound‐activated microbubbles as a novel intracellular drug delivery system for urinary tract infection
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.03.017
Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.004
Intestinal iontophoresis from mucoadhesive patches: a strategy for oral delivery
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.037
Poly(ethylene glycol)‐block‐poly(d,l‐lactic acid) micelles containing oligo(lactic acid)8‐paclitaxel prodrug: In Vivo conversion and antitumor efficacy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.017
Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.046
A nanoliter resolution implantable micropump for murine inner ear drug delivery
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.032
pH‐sensitive Eudragit® L 100 nanoparticles promote cutaneous penetration and drug release on the skin
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.045
Functional assessment of peptide‐modified PLGA nanoparticles against oral biofilms in a murine model of periodontitis
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.036
Hierarchical tumor acidity‐responsive self‐assembled magnetic nanotheranostics for bimodal bioimaging and photodynamic therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.03.019
Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.018
Stimulating brain recovery after stroke using theranostic albumin nanocarriers loaded with nerve growth factor in combination therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.11.017
A nano‐complex system to overcome antagonistic photo‐chemo combination cancer therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.043
Ulcerative colitis‐specific delivery of keratinocyte growth factor by neutrophils‐simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.034
Antimicrobial synergy of monolaurin lipid nanocapsules with adsorbed antimicrobial peptides against Staphylococcus aureus biofilms in vitro is absent in vivo
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.11.018
Thermosensitive nanocomposite gel for intra‐tumoral two‐photon photodynamic therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.019
Liposomal dexamethasone inhibits tumor growth in an advanced human‐mouse hybrid model of multiple myeloma
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.028
Modular core‐shell polymeric nanoparticles mimicking viral structures for vaccination
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.11.006
Microfluidic assembly of hydrogel‐based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.010
Novel auristatin E‐based albumin‐binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.010
Synchronous delivery of hydroxyapatite and connective tissue growth factor derived osteoinductive peptide enhanced osteogenesis
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.037
pH‐Sensitive morphological transitions in polymeric tadpole assemblies for programmed tumor therapy
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.10.033
Polymeric nanobiotics as a novel treatment for mycobacterial infections
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.10.009
Oligodepsipeptide (nano)carriers: Computational design and analysis of enhanced drug loading
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.03.004
PEGylated peptide to TIP1 is a novel targeting agent that binds specifically to various cancers in vivo
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.008
Smart triblock dendritic unimolecular micelles as pioneering nanomaterials: Advancement pertaining to architecture and biomedical applications
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.026
Nanohybrids – cancer theranostics for tiny tumor clusters
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.027
Glatiramer acetate persists at the injection site and draining lymph nodes via electrostatically‐induced aggregation
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.11.007
Silica cloaking of adenovirus enhances gene delivery while reducing immunogenicity
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.01.034
Radiolabeling of cell membrane‐based nano‐vesicles with 14C‐linoleic acid for robust and sensitive quantification of their biodistribution
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.005
A preclinical evaluation of a programmable CNT membrane device for transdermal nicotine delivery in hairless Guinea pigs
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.07.003
The antifibrotic potential of a sustained release formulation of a PDGF&bgr;‐receptor targeted rho kinase inhibitor
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.039
Sequential activation of anticancer therapy triggered by tumor microenvironment‐selective imaging
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2019.02.012
Anti‐tumour activity of low molecular weight heparin doxorubicin nanoparticles for histone H1 high‐expressive prostate cancer PC‐3M cells
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.034
Sequestering and inhibiting a vascular endothelial growth factor in vivo by systemic administration of a synthetic polymer nanoparticle
来源期刊：Journal of Controlled ReleaseDOI：10.1016/j.jconrel.2018.12.033
