Biological engineering is an emerging discipline that encompasses engineering theory and practice connected to and derived from the science of biology, just as mechanical engineering and electrical engineering are rooted in physics and chemical engineering in chemistry. Topical areas include, but are not limited to:Synthetic biology and cellular designBiomolecular, cellular and tissue engineering Bioproduction and metabolic engineeringBiosensorsEcological and environmental engineeringBiological engineering education and the biodesign processAs the official journal of the Institute of Biological Engineering, Journal of Biological Engineering provides a home for the continuum from biological information science, molecules and cells, product formation, wastes and remediation, and educational advances in curriculum content and pedagogy at the undergraduate and graduate-levels.Manuscripts should explore commonalities with other fields of application by providing some discussion of the broader context of the work and how it connects to other areas within the field.
生物工程是一门新兴学科，它包含与生物科学相关的工程理论和实践，就像机械工程和电气工程植根于物理学，化学工程植根于化学。主题领域包括，但不限于：合成生物学和细胞设计生物分子、细胞和组织工程生物生产和代谢工程生物传感器生态和环境工程生物工程教育和生物设计过程作为生物工程研究所的官方期刊，《生物工程杂志》提供了一个从生物信息科学、分子和细胞、产品形成、废物和修复，以及本科和研究生课程内容和教学法的教育进展的连续体的家园。稿件应通过提供一些工作的更广泛背景的讨论以及如何与该领域内的其他领域联系来探索与其他应用领域的共性。
Direct cell reprogramming for tissue engineering and regenerative medicine
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0144-9
Cardiac tissue engineering: state-of-the-art methods and outlook
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0185-0
Nucleic acid delivery to mesenchymal stem cells: a review of nonviral methods and applications
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0140-0
Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0189-9
Bioengineered models to study tumor dormancy
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-018-0137-0
Genetic circuits to engineer tissues with alternative functions
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0170-7
Microvascular bioengineering: a focus on pericytes
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0158-3
Follicle development as an orchestrated signaling network in a 3D organoid
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-018-0134-3
Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0148-5
Utilising datasheets for the informed automated design and build of a synthetic metabolic pathway
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0141-z
An overview of advanced biocompatible and biomimetic materials for creation of replacement structures in the musculoskeletal systems: focusing on cartilage tissue engineering
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0209-9
Polymer-based controlled-release fed-batch microtiter plate – diminishing the gap between early process development and production conditions
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0147-6
Using the promoters of MerR family proteins as “rheostats” to engineer whole-cell heavy metal biosensors with adjustable sensitivity
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0202-3
An injectable sulfonated reversible thermal gel for therapeutic angiogenesis to protect cardiac function after a myocardial infarction
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0142-y
Quantum dot therapeutics: a new class of radical therapies
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0173-4
Long-term continuous treatment of non-sterile real hospital wastewater by Trametes versicolor
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0179-y
The engineering principles of combining a transcriptional incoherent feedforward loop with negative feedback
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0190-3
A novel egg-shell membrane based hybrid nanofibrous scaffold for cutaneous tissue engineering
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0208-x
Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0165-4
Tools to reverse-engineer multicellular systems: case studies using the fruit fly
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0161-8
Directed evolution of the PcaV allosteric transcription factor to generate a biosensor for aromatic aldehydes
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0214-z
Computational analysis of viable parameter regions in models of synthetic biological systems
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0205-0
High capacity DNA data storage with variable-length Oligonucleotides using repeat accumulate code and hybrid mapping
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0211-2
Improved expansion of equine cord blood derived mesenchymal stromal cells by using microcarriers in stirred suspension bioreactors
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0153-8
Label-free and washing-free alkaline phosphatase assay using a personal glucose meter
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0182-3
Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0204-1
Electrospun nanofibers for the fabrication of engineered vascular grafts
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0199-7
Process development for pandemic influenza VLP vaccine production using a baculovirus expression system
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0206-z
Unique N-glycosylation of a recombinant exo-inulinase from Kluyveromyces cicerisporus and its effect on enzymatic activity and thermostability
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0215-y
Quantitative study of H protein lipoylation of the glycine cleavage system and a strategy to increase its activity by co-expression of LplA
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0164-5
HMEJ-mediated efficient site-specific gene integration in chicken cells
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0217-9
Novel biomanufacturing platform for large-scale and high-quality human T cells production
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0167-2
Expression profile analysis of long non-coding RNA in skeletal muscle of osteoporosis by microarray and bioinformatics
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0180-5
Transplantation of CRISPRa system engineered IL10-overexpressing bone marrow-derived mesenchymal stem cells for the treatment of myocardial infarction in diabetic mice
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0163-6
Identification of urban particulate matter-induced disruption of human respiratory mucosa integrity using whole transcriptome analysis and organ-on-a chip
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0219-7
Jamming state transition and collective cell migration
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0201-4
Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies in chinese hamster ovary cells
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0187-y
A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0171-6
Modified substrate specificity of a methyltransferase domain by protein insertion into an adenylation domain of the bassianolide synthetase
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0195-y
Mixture theory modeling for characterizing solute transport in breast tumor tissues
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0178-z
Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0207-y
Rise of the killer plants: investigating the antimicrobial activity of Australian plants to enhance biofilter-mediated pathogen removal
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0175-2
3D-tips: user-friendly mesh barrier pipette tips for 3D-spheroid culture
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0210-3
Engineered mosaic protein polymers; a simple route to multifunctional biomaterials
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0183-2
The effects of low-dose radiation on articular cartilage: a review
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-018-0125-4
Super-antibiofilm effect of N2 plasma treated buffer (NPB) against plant pathogenic bacterium
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0222-z
Marimo machines: oscillators, biosensors and actuators
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0200-5
Publisher Correction to: delivery systems of CRISPR/Cas9-based cancer gene therapy
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0169-0
Thematic series on emerging leaders in biological engineering: convergence and new directions
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0146-7
Correction to: Computational analysis of viable parameter regions in models of synthetic biological systems
来源期刊：Journal of Biological EngineeringDOI：10.1186/s13036-019-0213-0
