Nature Metabolism will publish work from across all fields of metabolism research that significantly advances our understanding of metabolic and homeostatic processes in a cellular or broader physiological context, from fundamental cell biology to basic biomedical and translational research. At its core, the research published in Nature Metabolism will shed light on how cellular metabolism informs cellular function, on the physiology and homeostasis of organs and tissues, on the regulation of organismal energy homeostasis, and on the molecular pathophysiology of metabolic diseases, such as diabetes and obesity, or the treatment thereof.
Nature Metabolism将发表所有代谢研究领域的成果,这些成果将显著推进我们对细胞或更广泛的生理学背景下的代谢和稳态过程的理解,从基础细胞生物学到基础生物医学和转化研究。发表在《自然代谢》杂志上的这项研究的核心内容将阐明细胞代谢如何影响细胞功能、器官和组织的生理学和稳态、有机体能量稳态的调节以及代谢疾病(如糖尿病和肥胖症)的分子病理生理学或其治疗。
Coupling Krebs cycle metabolites to signalling in immunity and cancer
来源期刊:Nature MetabolismDOI:10.1038/S42255-018-0014-7
Slc12a8 is a nicotinamide mononucleotide transporter
来源期刊:Nature metabolismDOI:10.1038/s42255-018-0009-4
Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis
来源期刊:Nature metabolismDOI:10.1038/s42255-018-0011-x
Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0035-x
TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism
来源期刊:Nature metabolismDOI:10.1038/S42255-018-0030-7
Liver macrophages regulate systemic metabolism through non-inflammatory factors
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0044-9
Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0075-2
Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0101-4
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0146-4
Dynamic interactions of ABHD5 with PNPLA3 regulate triacylglycerol metabolism in brown adipocytes
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0066-3
MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage
来源期刊:Nature metabolismDOI:10.1038/S42255-018-0023-6
m6A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0089-9
Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0083-2
Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling
来源期刊:Nature metabolismDOI:10.1038/s42255-018-0005-8
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0061-8
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0120-1
Soluble RANKL is physiologically dispensable but accelerates tumour metastasis to bone
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0104-1
Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0081-4
Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0084-1
Role and therapeutic potential of dietary ketone bodies in lymph vessel growth.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0087-Y
Hypothalamic dopamine signalling regulates brown fat thermogenesis
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0099-7
A biosensor for measuring NAD+ levels at the point of care.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0151-7
Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0135-7
GIP regulates inflammation and body weight by restraining myeloid-cell-derived S100A8/A9
来源期刊:Nature MetabolismDOI:10.1038/S42255-018-0001-Z
Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus
来源期刊:Nature metabolismDOI:10.1038/s42255-018-0029-0
Oncogenic Rag GTPase signaling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0098-8
The long noncoding RNA lnc-ob1 facilitates bone formation by upregulating Osterix in osteoblasts
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0053-8
Hypothalamic microglia as potential regulators of metabolic physiology
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0040-0
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0124-x
Autophagic lipid metabolism sustains mTORC1 activity in TSC-deficient neural stem cells
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0137-5
Control strategies in systemic metabolism
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0118-8
The long noncoding RNA CHROME regulates cholesterol homeostasis in primate
来源期刊:Nature metabolismDOI:10.1038/s42255-018-0004-9
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0055-6
Go with the flow—hidden vascular passages in bone
来源期刊:Nature MetabolismDOI:10.1038/S42255-018-0024-5
SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0136-6
Age is in the nucleus.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0125-9
Mitochondrial haplotypes affect metabolic phenotypes in the Drosophila Genetic Reference Panel
来源期刊:Nature MetabolismDOI:10.1038/s42255-019-0147-3
Endothelial metabolism—more complex (III) than previously thought
来源期刊:Nature MetabolismDOI:10.1038/S42255-018-0019-2
Author Correction: Liver macrophages regulate systemic metabolism through non-inflammatory factors
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0062-7
Transforming endothelial cells in atherosclerosis.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0100-5
Pancreatic β-cell mRNA modification as a marker for type 2 diabetes.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0096-X
NAD+: a metabolic knob fine-tuning inflammation during senescence
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0047-6
Exocrine or endocrine? A circulating pancreatic elastase that regulates glucose homeostasis.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0107-Y
Speed-dieting: dopamine agonists promote weight loss.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0114-z
Radical sensing keeps noxious iron at bay
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0070-7
Author Correction: Transcriptional network analysis implicates altered hepatic immune function in NASH development and resolution.
来源期刊:Nature metabolismDOI:10.1038/S42255-019-0093-0
Essentiality of non-essential amino acids for tumour cells and tumorigenesis.
来源期刊:Nature metabolismDOI:10.1038/s42255-019-0113-0
Microbiome genetics links short-chain fatty acids to metabolic diseases
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0056-5
Lipase tug of war: PNPLA3 sequesters ABHD5 from ATGL
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0067-2
Divide and hide: proliferating β-cells control immune tolerance in autoimmune diabetes
来源期刊:Nature MetabolismDOI:10.1038/S42255-019-0068-1