The American Journal of Physiology-Endocrinology and Metabolism publishes original, mechanistic studies on the physiology of endocrine and metabolic systems. Physiological, cellular, and molecular studies in whole animals or humans will be considered. Specific themes include, but are not limited to, mechanisms of hormone and growth factor action; hormonal and nutritional regulation of metabolism, inflammation, microbiome and energy balance; integrative organ cross talk; paracrine and autocrine control of endocrine cells; function and activation of hormone receptors; endocrine or metabolic control of channels, transporters, and membrane function; temporal analysis of hormone secretion and metabolism; and mathematical/kinetic modeling of metabolism. Novel molecular, immunological, or biophysical studies of hormone action are also welcome.
Intact innervation is essential for diet-induced recruitment of brown adipose tissue
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00443.2018
In the absence of UCP1-mediated diet-induced thermogenesis, obesity is augmented even in the obesity-resistant 129S mouse strain
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00020.2019
The gut microbiota is a major regulator of androgen metabolism in intestinal contents
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00338.2019
Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00161.2019
Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00065.2019
Hepatic MyD88 regulates liver inflammation by altering synthesis of oxysterols
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00082.2019
Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00407.2018
Repetitive hypoglycemia reduces activation of glucose-responsive neurons in C1 and C3 medullary brain regions to subsequent hypoglycemia
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00051.2019
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia
来源期刊:American Journal of Physiology - Endocrinology and MetabolismDOI:10.1152/ajpendo.00253.2019