The Journal of Biomolecular NMR provides a forum for publishing research on technical developments and innovative applications of nuclear magnetic resonance spectroscopy for the study of structure and dynamic properties of biopolymers in solution, liquid crystals, solids and mixed environments, e.g., attached to membranes. This may include:Three-dimensional structure determination of biological macromolecules (polypeptides/proteins, DNA, RNA, oligosaccharides) by NMR.New NMR techniques for studies of biological macromolecules.Novel approaches to computer-aided automated analysis of multidimensional NMR spectra.Computational methods for the structural interpretation of NMR data, including structure refinement.Comparisons of structures determined by NMR with those obtained by other methods, e.g. by diffraction techniques with protein single crystals.New techniques of sample preparation for NMR experiments (biosynthetic and chemical methods for isotope labeling, preparation of nutrients for biosynthetic isotope labeling, etc.). An NMR characterization of the products must be included.
《生物分子核磁共振杂志》提供了一个论坛,发表有关核磁共振波谱技术发展和创新应用的研究成果,用于研究溶液、液晶、固体和混合环境中生物聚合物的结构和动态特性,附着在膜上。这可能包括:用NMR测定生物大分子(多肽/蛋白质、DNA、RNA、寡糖)的三维结构;研究生物大分子的新NMR技术;计算机辅助自动分析多维NMR谱的新方法; NMR数据结构解释的计算方法,包括结构精化; NMR测定的结构与其他方法获得的结构的比较,例如用蛋白质单晶衍射技术; NMR实验样品制备的新技术(同位素标记的生物合成和化学方法,生物合成同位素标记用营养物的制备等)。必须包括产品的NMR表征。
Spinning faster: protein NMR at MAS frequencies up to 126 kHz
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-018-0219-9
Increasing the buffering capacity of minimal media leads to higher protein yield
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-018-00222-4
Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00250-8
Investigation of the internal structure and dynamics of cellulose by 13C-NMR relaxometry and 2DPASS-MAS-NMR measurements.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00272-2
Assessing the potential of quantitative 2D HSQC NMR in 13C enriched living organisms
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-018-0221-2
Using Deep Neural Networks to Reconstruct Non-uniformly Sampled NMR Spectra
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00265-1
NMRlib: user-friendly pulse sequence tools for Bruker NMR spectrometers
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00249-1
NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00234-8
NMR characterization of solvent accessibility and transient structure in intrinsically disordered proteins
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00248-2
Validation of protein backbone structures calculated from NMR angular restraints using Rosetta
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00251-7
NMR-STAR: comprehensive ontology for representing, archiving and exchanging data from nuclear magnetic resonance spectroscopic experiments
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-018-0220-3
19F NMR relaxation studies of fluorosubstituted tryptophans.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00268-y
NMR-based fragment screening and lead discovery accelerated by principal component analysis.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00279-9
Random coil chemical shifts for serine, threonine and tyrosine phosphorylation over a broad pH range
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00283-z
Hybridization of TEDOR and NCX MAS solid-state NMR experiments for simultaneous acquisition of heteronuclear correlation spectra and distance measurements
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00237-5
Perspective: the essential role of NMR in the discovery and characterization of intrinsically disordered proteins.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00280-2
Importance of time-ordered non-uniform sampling of multi-dimensional NMR spectra of Aβ1-42 peptide under aggregating conditions.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00235-7
Assigning NMR spectra of RNA, peptides and small organic molecules using molecular network visualization software
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00271-3
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00246-4
Random coil shifts of posttranslationally modified amino acids
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00270-4
Accuracy and precision of protein structures determined by magic angle spinning NMR spectroscopy: for some ‘with a little help from a friend’
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00233-9
Maximizing accuracy of RNA structure in refinement against residual dipolar couplings
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00236-6
Accelerating 2D NMR relaxation dispersion experiments using iterated maps.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00263-3
A unified structural model of the mammalian translocator protein (TSPO).
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00257-1
Paramagnetic-iterative relaxation matrix approach: extracting PRE-restraints from NOESY spectra for 3D structure elucidation of biomolecules.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00282-0
Intra-residue methyl–methyl correlations for valine and leucine residues in large proteins from a 3D-HMBC-HMQC experiment
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00287-9
2-Fluorotyrosine is a valuable but understudied amino acid for protein-observed 19F NMR.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00290-0
Feasibility of trifluoromethyl TROSY NMR at high magnetic fields.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00266-0
NMR and MD studies combined to elucidate inhibitor and water interactions of HIV-1 protease and their modulations with resistance mutations.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00260-6
Solution structure of the N-terminal domain of the Staphylococcus aureus hibernation promoting factor
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00254-4
Complete protein assignment from sets of spectra recorded overnight
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00226-8
The NMR signature of gluconoylation: a frequent N-terminal modification of isotope-labeled proteins
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00228-6
Detection of chemical exchange in methyl groups of macromolecules.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00240-w
Non-uniform sampling in quantitative assessment of heterogeneous solid-state NMR line shapes
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00291-z
Investigation of backbone dynamics and local geometry of bio-molecules using calculated NMR chemical shifts and anisotropies.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00284-y
Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00281-1
Exchangeable deuterons introduce artifacts in amide 15N CEST experiments used to study protein conformational exchange
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-018-00223-3
Accurate measurement of dipole/dipole transverse cross-correlated relaxation $$\\varGamma _2$$Γ2 in methylenes and primary amines of uniformly $${}^{13}\\text {C}/{}^{15}\\text {N}$$13C/15N-labeled proteins
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00252-6
Accounting for the temperature dependence of 13C spin–lattice relaxation of methyl groups in the glycyl–alanyl-leucine model system under MAS with spin diffusion
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00261-5
Partial alignment, residual dipolar couplings and molecular symmetry in solution NMR.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00256-2
Site-selective 1H/2H labeling enables artifact-free 1H CPMG relaxation dispersion experiments in aromatic side chains
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00275-z
Determination of methyl order parameters using solid state NMR under off magic angle spinning.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00253-5
Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00242-8
A simple protocol for expression of isotope-labeled proteins in Escherichia coli grown in shaker flasks at high cell density.
来源期刊:Journal of biomolecular NMRDOI:10.1007/s10858-019-00285-x
Conformational flexibility of adenine riboswitch aptamer in apo and bound states using NMR and an X-ray free electron laser
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00278-w
XIPP: multi-dimensional NMR analysis software
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00286-w
Correction to: Joint X-ray/NMR structure refinement of multidomain/multisubunit systems
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00238-4
Time-domain signal modelling in multidimensional NMR experiments for estimation of relaxation parameters
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-018-00224-2
Enhancing NMR derived ensembles with kinetics on multiple timescales
来源期刊:Journal of Biomolecular NmrDOI:10.1007/s10858-019-00288-8
Super resolution NOESY spectra of proteins
来源期刊:Journal of Biomolecular NMRDOI:10.1007/s10858-019-00231-x